News: Leibniz-FMP

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Following a competitive review, the German Research Foundation (DFG) recently announced that the Cluster of Excellence NeuroCure will be extended for another term, receiving…

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Problems speaking or walking, muscle tremors, and seizures – in a large interdisciplinary collaboration, researchers led by Noa Lipstein and Nils Brose have discovered a new…

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Tubulis, a company spun off of the Leibniz-Forschungsinstitut für Molekulare Pharmakologie (FMP) and LMU Munich in 2019, has announced positive early clinical data from the…

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Prof. Dr. Volker Haucke, Director at the Leibniz-Forschungsinstitut für Molekulare Pharmakologie (FMP) and Professor of Molecular Pharmacology at Freie Universität Berlin,…

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The Ernst Schering Prize 2025, endowed with 50.000 euros, is awarded to Prof. Dr. Volker Haucke, Director at the Leibniz-Forschungsinstitut für Molekulare Pharmakologie…

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For his research on lysosomes, the cell biologist Michael Ebner has received one of the coveted ERC Starting Grants from the European Research Council (ERC). The scientist…

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A research team has gained new insights into the molecular processes of clathrin-mediated endocytosis – the central process by which cells take up nutrients, messenger…

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Modern drugs such as semaglutide (Ozempic/Wegovy) and tirzepatide (Mounjaro/Zepbound) are…

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Institute & Campus

The Long Night of the Sciences has been taking place for 25 years - and the Leibniz-Forschungsinstitut für Molekulare Pharmakologie was again part of it this year. With many…

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Institute & Campus

110 scientists are clearly committed to animal research. One of them is Prof. Dr. Volker Haucke, Director at the Leibniz-Forschungsinstitut für Molekulare Pharmakologie…

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Regulated transport of ions, such as sodium or chloride, across biological membranes is…

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Tubulis (a joint spin-off of the FMP and the Ludwig-Maximilians-Universität Munich) announced today that its second drug candidate, TUB-030, has entered clinical evaluation…

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Leibniz-Forschungsinstitut für Molekulare Pharmakologie (FMP) in Berlin, the Faculty of Medicine at Kiel University, and the Leibniz Institute of Virology in Hamburg are…

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WSR081 - Interview mit Dr. Johannes Broichhagen

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The Einstein Foundation in cooperation with BIH QUEST Center for Responsible Research awards Christopher Schmied (Leibniz-Forschungsinstitut für Molekulare Pharmakologie und…

Biological samples are taken from a nitrogen tank.

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What role do certain lipids, known as phosphoinositides (PIPs), play in obesity and other metabolic diseases? This is now being investigated by scientists from the…

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AP180 is a protein involved in endocytosis and thus in signal transmission between nerve cells. This protein, which largely lacks a three-dimensional structure, has never…

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A team led by Prof. Dr. Han Sun from the Leibniz-Forschungsinstitut für Molekulare Pharmakologie (FMP) has elucidated an important mechanism in the function of TREK channels…

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A new NMR spectrometer has been in operation at the Leibniz-Forschungsinstitut für Molekulare Pharmakologie (FMP) since the end of May. What makes it special is that it is…

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Groundbreaking innovations by researchers at the Leibniz-Forschungsinstitut für Molekulare Pharmakologie (FMP) provided the basis for the development of an antibody-drug…

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Prof. Dr. Fan Liu from the Leibniz-Forschungsinstitut für Molekulare Pharmakologie (FMP) has recently received several awards for her contributions to the field of…

Radoslaw Wesolowski (left), Michael Bader (center) and Dr. Edgar Specker

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Diseases can emerge when the body’s production of serotonin is out of whack. Researchers led by Michael Bader from the Max Delbrück Center have discovered a therapeutic…

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Lysosomes play an important role in cells and tissues, controlling not only the degradation of substances but also cell division and growth. A team led by Professor Volker…

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Institute & Campus

Der Campus Berlin-Buch hat ein neues Gründerzentrum: Am 11. Oktober 2023 wurde der BerlinBioCube im Beisein des Regierenden Bürgermeisters feierlich eröffnet.

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graphical Abstract of publications output

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As part of a global initiative, researchers have drawn up guidelines for the publication of microscopy images in scientific outlets. The criteria, summarized in the form of…

Visualization brain and neuronal circuits

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Visualization Brain and Neuronal Circuit

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Our behavior is controlled through neural circuits in the brain. Molecular disturbances can lead to stereotypical behavior, as seen in neuropsychiatric disorders like…

Model of herpesviral virions in cross-section

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Once infected - always infected: Herpes viruses lie dormant in the body and can be reactivated by certain circumstances. The herpes virus HCMV is particularly widespread,…

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Rhomboid proteases are a promising target for new drugs. Now researchers from the Leibniz-Forschungsinstitut für Molekulare Pharmakologie (FMP) have uncovered a mechanism…

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The discussion about the amendment of the Wissenschaftszeitvertragsgesetz (WissZeitVG) has been intense and controversial in recent months. In the meantime, the BMBF has…

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Das Leibniz-Forschungsinstitut für Molekulare Pharmakologie (FMP) wurde am 13. Juni 2023 in Berlin im Rahmen der 25. Zertifikatsverleihung der berufundfamilie für seine…

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Wissenschaftsteams des Max Delbrück Center und seiner Partnerinstitutionen haben im Jahr 2022 insgesamt 54.402 Tiere in Versuchen eingesetzt. Diese Zahlen wurden jetzt an…

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Institute & Campus

Für attraktive wissenschaftliche Karrieren in Deutschland

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The association of Berlin's non-university research institutions, Berlin Research 50 (BR50), rejects the draft of the Wissenschaftszeitvertragsgesetz (WissZeitVG) presented…

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Institute & Campus

Die Landesrunde des Wettbewerbs „Chemie- die stimmt!“ fand am 22. März 2023 mit 60 Teilnehmer:innen und Teilnehmern auf dem Campus Berlin-Buch statt.

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Institute & Campus

Armaghan Naghipour, Staatssekretärin für Wissenschaft, Forschung und Gleichstellung, informierte sich am 10. Februar 2023 über die Entwicklung des Wissenschafts- und…

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The European Innovation Council Pathfinder Challenges program funds the international research consortium “Supervised Morphogenesis in Gastruloids” – SUMO

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Sulfates are essential to maintain a healthy life and the kidney plays a central role in transporting sulfate from tubular fluid, thereby retaining it in the…

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Body cells burn off fat reserves when nutrient supply from food ceases. A team led by Professor Volker Haucke and Dr. Wonyul Jang from the Leibniz-Forschungsinstitut für…

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Christian Hackenberger reported on new approaches from chemistry for medicine during ARDalpha's Campus Talks. (in German)

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Internationales Antivirus-Projekt MUCBOOST um Dr. Daniel Lauster vom Institut für Chemie und Biochemie erhält rund 1,5 Millionen Euro / eines von sechs ausgezeichneten…

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The lipid kinase PI3KC2α is a potential pharmacological target for the treatment of thrombosis and, possibly, cancer. Researchers from the Leibniz-Forschungsinstitut für…

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They seal epithelial cells and, under certain conditions, allow the passage of ions and water: Tight junctions form a paracellular barrier in tissues and their dysfunction…

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Würdigung von zwei bedeutenden Wissenschaftlerinnen des 20. Jahrhunderts

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A harmful and often deadly substance made by bacteria, a bacterial toxin manipulates host cell functions and disrupts vital cell processes in a living organism. Bacterial…

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New technology of Antibody Drug Conjugates (ADCs)

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Treating cancer more selectively and more effectively – this could be achieved with an…

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Since the discovery of the chloride ion channel ASOR three years ago, researchers have been searching for its biological functions. Now, the team led by Prof. Thomas Jentsch…

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The company Tubulis announced today the closing of a Series B financing round totaling €60 million to advance the development of a novel class of highly stable and efficient…

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Using the Hyper-CEST NMR technique, the team led by Leif Schröder from the Leibniz-Forschungsinstitut für Molekulare Pharmakologie (FMP) and the Deutsches…

Live cell imaging of native cell surface receptors

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The prestigious Starting Grant from the European Research Council (ERC) was awarded to Dr. Johannes Broichhagen from the Leibniz-Forschungsinstitut für Molekulare…

Structural model of active PI3KC2α at the plasma membrane

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Phosphatidylinositol 3-kinase, or PI3K for short, is a family of lipid kinases that plays a key role in the human body, performing functions such as cell division,…

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Institute & Campus

Von einer Schul-App für Covid-Schnelltests über Methoden der Makrofotografie bis zum smarten Rollator – beim 57. Regionalwettbewerb wurden in Buch viele spannende Projekte…

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Tiny ion channels are responsible for transporting potassium and sodium to our cells. In the process, ions must pass through a bottleneck, referred to as the selectivity…

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The chloride ion channel ASOR is found in almost all our cells. But apart from its involvement in cell death, not much is known about its physiological role. Two years ago,…

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The prestigious Starting Grant from the European Research Council (ERC) was awarded to Dr. Marijn Kuijpers from the Leibniz-Forschungsinstitut für Molekulare Pharmakologie…

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The potassium channel KCNQ3 is required for our brain to generate accurate spatial maps. In mice, defects in KCNQ3 function have measurable effects on the internal…

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It is one of the big pharmacological questions: How do you get large functional biomolecules like proteins or antibodies into a living cell? Linking antibodies or proteins…

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Das Immunsystem mit Kefirknollen stärken, intelligente Straßenmodelle entwickeln, ein Programm für chemische Reaktionen schreiben: Die Gewinner*innen des 56.…

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Chemotherapy is often unable to ensure adequate destruction of dormant cancer cells that have detached from the primary tumor and are circulating in the bloodstream. Sooner…

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Xenon magnetic resonance imaging offers deep insights into the human body and opens up new possibilities in the diagnosis and treatment of diseases. Physicists from the…

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Die Deutsche Forschungsgemeinschaft (DFG) hat einen Sonderforschungsbereich (SFB) neu bewilligt. Die Forschenden untersuchen anhand der Atemwege und des Darms Dynamische…

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A mutation in the CLCN6 gene is associated with a novel, particularly severe neurodegenerative disorder. Scientists from the Leibniz-Forschungsinstitut für Molekulare…

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Given that phages are able to destroy bacteria, they are of particular interest to science. Basic researchers from the Leibniz-Forschungsinstitut für Molekulare…

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Christian Hackenberger is honored at the Falling Walls conference with a “breakthrough of the year”-award in the life sciences. Ten scientific "breakthroughs of the year"…

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It appears that autophagy protects our neurons in the brain, but evidently for entirely different reasons than previously assumed, as researchers from the…

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Prof. Dr. Fan Liu from the Leibniz-Forschungsinstitut für Molekulare Pharmakologie (FMP) receives a prestigious ERC Starting Grant of the European Research Council (ERC).…

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The young company Tubulis announced today the closure of a Series A funding round totaling €10.7 million to advance the development of a novel class of highly stable and…

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Professor Volker Haucke from the Leibniz-Forschungsinstitut für Molekulare Pharmakologie (FMP) and the Freie Universität Berlin receives a prestigious ERC Advanced Grant of…

visualization of the method; peptides in a spa

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>>>>>>>>>>>>>>>>NEW METHOD Proteins transmit signals in cells, whereby faulty signal transduction can lead to diseases such as cancer. Chemist Sandra Schlomach has…

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>>>>>>>>>>>>>>>LESS SIDE EFFECTS To effectively reach and eliminate tumor cells, a molecular transporter must deliver the cytotoxin with pinpoint accuracy. This can…

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Rhomboid proteases are clinically relevant membrane proteins that play a key role in various diseases. Using solid-state NMR spectroscopy, researchers from Berlin’s…

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Treating cancer more selectively and more effectively – this could be achieved with an innovative technology developed by teams of researchers at the…

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Prof. Volker Haucke, Director at the Leibniz-Forschungsinstitut für Molekulare Pharmakologie (FMP) receives the Feldberg Prize 2020, which is awarded annually by the…

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Synapses are the interfaces for information exchange between neurons. Teams of scientists working with Professor Dr. Volker Haucke, Director at the…

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Cluster of Excellence NeuroCure: Insights into research and future prospects

New developmental disorder discovered: Variations in the UNC13A gene cause neurological impairments in children

FMP-and LMU-spin-off Tubulis presents first clinical data on TUB-040 in platinum-resistant ovarian cancer (PROC) at the ESMO Congress 2025

How synapses are formed: DFG once again funds cutting-edge research by Volker Haucke

Volker Haucke receives the Ernst Schering Prize 2025

Michael Ebner receives 1.5 million euros in funding from the European Research Council (ERC)

New dynamics in endocytosis: proteins build flexible networks for transporting molecules

Searching for clues with fluorescent markers: International study reveals mechanisms of action of diabetes and obesity drugs

The Long Night of the Sciences 2025

"We conduct animal testing!"

Newly discovered subunits of chloride transporters shed light on the mechanism of severe neurological diseases

Volker Haucke honored with the Leibniz Prize 2025 of the German Research Foundation

Tubulis Announces First Patient Dosed in Phase I/IIa Trial Evaluating ADC TUB-030 in Advanced Solid Tumors

New Insights into the Mechanisms of Potassium Channels for Medicine

ChemBioProbes: Sonden für Diagnose und Therapie

Einstein Foundation Early Career Award for Christopher Schmied and Helena Jambor

From Molecule to Disease: PIPs Project of the Leibniz Cooperative Excellence Launched

Endocytosis: New interaction network discovered

Mechanism of phosphorylation in TREK channels offers therapeutic potential

Giant with a Ceramic Heart

Novel Cancer Therapeutic from FMP Research Enters Clinical Phase

Explore now: Research Highlights

The Protein Expert

New agent regulates serotonin production

Lysosomes prove to be quick-change artists

Boost für Biotech-Branche in Berlin

Mechanism decoded: how synapses are formed

Global guidelines to improve the quality of microscopy images in scientific publications

Deficiency in certain brain proteins promotes compulsive behavior

Deficiency in certain brain proteins promotes compulsive behavior

Came to stay: How the herpes virus HCMV deceives its host cells

Came to stay: How the herpes virus HCMV deceives its host cells

How rhomboid protease activity is regulated

How rhomboid protease activity is regulated

Statement of the undersigned professional societies in the field of natural and life sciences on the draft bill of the amendment of the Wissenschaftszeitvertragsgesetz (WissZeitVG - German Act on Temporary Scientific Contracts)

Weiterentwicklung im und mit dem Wandel: FMP erneut für systematische Vereinbarkeitspolitik ausgezeichnet

Versuchstiermeldung für das Jahr 2022

Stellungnahme der Allianz der Wissenschaftsorganisationen

Non-university research institutions see cutting-edge research in danger. BR50 calls for revision of planned reform of WissZeitVG

Chemie - die stimmt! Chemieolympiade für Schülerinnen und Schüler der Klassen 8 bis 10

Staatssekretärin Naghipour besucht den Campus Berlin-Buch

European funding for research on emerging breakthrough technology

International Day of Women and Girls in Science February 11

Celebrating the Diversity of Science - our new video!

How the kidney maintains sulfate homeostasis in the body

Starvation causes cell remodelling

How do drugs reach their destination in the body in a safe way?

Bundesagentur für Sprunginnovationen fördert Vorhaben zur Entwicklung antiviraler Mittel

Inhibitor of lipid kinase PI3KC2α identified as potential new treatment of thrombosis

How do we design small molecules to target diseases?

Dense and permeable: molecular organization of tight junctions decoded

Büsten von Marguerite und Marthe Vogt enthüllt

Mechanism of bacterial toxins in deadly attacks

Remembering your first kiss: How do synapses work?

Fewer side-effects: How we deliver drugs to tumor cells

Chloride ion channel ASOR is required for vesicle shrinkage

FMP & LMU spin-off Tubulis closes €60 million Series B financing to accelerate its ADC Pipeline

How do we study proteins with atomic precision?

Hyper-CEST NMR technique reveals missing structure of a novel container molecule

Exploring the effect of isotopes in Chemical Biology – Johannes Broichhagen receives 1.5 Million Euros of Funding from the European Research Council (ERC)

Class II PI3K lipid kinase: Structure of novel drug target resolved

Campus Berlin-Buch kürt Regional-Sieger von „Jugend forscht“

New insights: how potassium and sodium are conducted through ion channels

Solving puzzles of the chloride ion channel ASOR

Understanding the role of the largest organelle in nerve cells - Marijn Kuijpers receives 1.5 Million Euros of Funding from the European Research Council (ERC)

A defective potassium channel disrupts the brain's navigation system.

Large Molecules Transported into Living Cells: Researchers Achieve Breakthrough into Cell Interior

Zukunftsfähige Ideen im Wettbewerb „Jugend forscht“

Disorientating dormant tumor cells

Enhanced speed, contrast, and information: New contrast mechanism improves xenon MRI

Neuer Sonderforschungsbereich über Hydrogele an Grenzflächen und verlängerter SFB 1078, beide mit Beteiligung des FMP

CLCN6 identified as disease gene for a severe form of lysosomal neurodegenerative disease

Light shed on the atomic resolution structure of phage DNA tube – a methodological milestone

Christian Hackenberger receives breakthrough award in life sciences at the Berlin Science Week

Surprising insights into the role of autophagy in neurons

Fan Liu receives 1.5 Million Euros of Funding from the European Research Council (ERC)

FMP spin-off Tubulis acquires €10.7 million for the development of novel antibody drug conjugates (ADCs)

Understanding the Formation of Nerve Cell Contacts - Volker Haucke receives 2.5 Million Euros of Funding from the European Research Council (ERC)

How do we study signaling pathways within the cell?