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Radoslaw Wesolowski (left), Michael Bader (center) and Dr. Edgar Specker

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New agent regulates serotonin production

Diseases can emerge when the body’s production of serotonin is out of whack. Researchers led by Michael Bader from the Max Delbrück Center have discovered a therapeutic…

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Lysosomes prove to be quick-change artists

Lysosomes play an important role in cells and tissues, controlling not only the degradation of substances but also cell division and growth. A team led by Professor Volker…

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Institute & Campus

Boost für Biotech-Branche in Berlin

Der Campus Berlin-Buch hat ein neues Gründerzentrum: Am 11. Oktober 2023 wurde der BerlinBioCube im Beisein des Regierenden Bürgermeisters feierlich eröffnet.

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Mechanism decoded: how synapses are formed


Vizualisation neurons

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Mechanism decoded: how synapses are formed

How are synapses formed, those points of contact that allow the transmission of information from one neuron to the other? Working with an international team, researchers…

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Global guidelines to improve the quality of microscopy images in scientific publications

As part of a global initiative, researchers have drawn up guidelines for the publication of microscopy images in scientific outlets. The criteria, summarized in the form of…

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Deficiency in certain brain proteins promotes compulsive behavior


Visualization Brain and Neuronal Circuit

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Deficiency in certain brain proteins promotes compulsive behavior

Our behavior is controlled through neural circuits in the brain. Molecular disturbances can lead to stereotypical behavior, as seen in neuropsychiatric disorders like…

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Came to stay: How the herpes virus HCMV deceives its host cells

Once infected - always infected: Herpes viruses lie dormant in the body and can be reactivated by certain circumstances. The herpes virus HCMV is particularly widespread,…

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Came to stay: How the herpes virus HCMV deceives its host cells


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How rhomboid protease activity is regulated


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How rhomboid protease activity is regulated

Rhomboid proteases are a promising target for new drugs. Now researchers from the Leibniz-Forschungsinstitut für Molekulare Pharmakologie (FMP) have uncovered a mechanism…

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Statement of the undersigned professional societies in the field of natural and life sciences on the draft bill of the amendment of the Wissenschaftszeitvertragsgesetz (WissZeitVG - German Act on Temporary Scientific Contracts)

The discussion about the amendment of the Wissenschaftszeitvertragsgesetz (WissZeitVG) has been intense and controversial in recent months. In the meantime, the BMBF has…

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Weiterentwicklung im und mit dem Wandel: FMP erneut für systematische Vereinbarkeitspolitik ausgezeichnet

Das Leibniz-Forschungsinstitut für Molekulare Pharmakologie (FMP) wurde am 13. Juni 2023 in Berlin im Rahmen der 25. Zertifikatsverleihung der berufundfamilie für seine…

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Versuchstiermeldung für das Jahr 2022

Wissenschaftsteams des Max Delbrück Center und seiner Partnerinstitutionen haben im Jahr 2022 insgesamt 54.402 Tiere in Versuchen eingesetzt. Diese Zahlen wurden jetzt an…

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Stellungnahme der Allianz der Wissenschaftsorganisationen

Für attraktive wissenschaftliche Karrieren in Deutschland

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Non-university research institutions see cutting-edge research in danger. BR50 calls for revision of planned reform of WissZeitVG

The association of Berlin's non-university research institutions, Berlin Research 50 (BR50), rejects the draft of the Wissenschaftszeitvertragsgesetz (WissZeitVG) presented…

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Institute & Campus

Chemie - die stimmt! Chemieolympiade für Schülerinnen und Schüler der Klassen 8 bis 10

Die Landesrunde des Wettbewerbs „Chemie- die stimmt!“ fand am 22. März 2023 mit 60 Teilnehmer:innen und Teilnehmern auf dem Campus Berlin-Buch statt.

Staatssekretärin Naghipour

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Staatssekretärin Naghipour besucht den Campus Berlin-Buch

Armaghan Naghipour, Staatssekretärin für Wissenschaft, Forschung und Gleichstellung, informierte sich am 10. Februar 2023 über die Entwicklung des Wissenschafts- und…

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European funding for research on emerging breakthrough technology

The European Innovation Council Pathfinder Challenges program funds the international research consortium “Supervised Morphogenesis in Gastruloids” – SUMO

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International Day of Women and Girls in Science February 11


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Celebrating the Diversity of Science - our new video!


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How the kidney maintains sulfate homeostasis in the body

Sulfates are essential to maintain a healthy life and the kidney plays a central role in transporting sulfate from tubular fluid, thereby retaining it in the…

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Starvation causes cell remodelling

Body cells burn off fat reserves when nutrient supply from food ceases. A team led by Professor Volker Haucke and Dr. Wonyul Jang from the Leibniz-Forschungsinstitut für…

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How do drugs reach their destination in the body in a safe way?

Christian Hackenberger reported on new approaches from chemistry for medicine during ARDalpha's Campus Talks. (in German)

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Bundesagentur für Sprunginnovationen fördert Vorhaben zur Entwicklung antiviraler Mittel

Internationales Antivirus-Projekt MUCBOOST um Dr. Daniel Lauster vom Institut für Chemie und Biochemie erhält rund 1,5 Millionen Euro / eines von sechs ausgezeichneten…

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Inhibitor of lipid kinase PI3KC2α identified as potential new treatment of thrombosis

The lipid kinase PI3KC2α is a potential pharmacological target for the treatment of thrombosis and, possibly, cancer. Researchers from the Leibniz-Forschungsinstitut für…

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How do we design small molecules to target diseases?


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Dense and permeable: molecular organization of tight junctions decoded

They seal epithelial cells and, under certain conditions, allow the passage of ions and water: Tight junctions form a paracellular barrier in tissues and their dysfunction…

Bueste Marthe Vogt

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Institute & Campus

Büsten von Marguerite und Marthe Vogt enthüllt

Würdigung von zwei bedeutenden Wissenschaftlerinnen des 20. Jahrhunderts

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Mechanism of bacterial toxins in deadly attacks

A harmful and often deadly substance made by bacteria, a bacterial toxin manipulates host cell functions and disrupts vital cell processes in a living organism. Bacterial…

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Remembering your first kiss: How do synapses work?


New technology of Antibody Drug Conjugates (ADCs)

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Fewer side-effects: How we deliver drugs to tumor cells

Treating cancer more selectively and more effectively – this could be achieved with an…


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Chloride ion channel ASOR is required for vesicle shrinkage

Since the discovery of the chloride ion channel ASOR three years ago, researchers have been searching for its biological functions. Now, the team led by Prof. Thomas Jentsch…

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FMP & LMU spin-off Tubulis closes €60 million Series B financing to accelerate its ADC Pipeline

The company Tubulis announced today the closing of a Series B financing round totaling €60 million to advance the development of a novel class of highly stable and efficient…

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How do we study proteins with atomic precision?


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Hyper-CEST NMR technique reveals missing structure of a novel container molecule

Using the Hyper-CEST NMR technique, the team led by Leif Schröder from the Leibniz-Forschungsinstitut für Molekulare Pharmakologie (FMP) and the Deutsches…

Live cell imaging of native cell surface receptors

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Exploring the effect of isotopes in Chemical Biology – Johannes Broichhagen receives 1.5 Million Euros of Funding from the European Research Council (ERC)

The prestigious Starting Grant from the European Research Council (ERC) was awarded to Dr. Johannes Broichhagen from the Leibniz-Forschungsinstitut für Molekulare…

Structural model of active PI3KC2α at the plasma membrane

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Class II PI3K lipid kinase: Structure of novel drug target resolved

Phosphatidylinositol 3-kinase, or PI3K for short, is a family of lipid kinases that plays a key role in the human body, performing functions such as cell division,…

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Campus Berlin-Buch kürt Regional-Sieger von „Jugend forscht“

Von einer Schul-App für Covid-Schnelltests über Methoden der Makrofotografie bis zum smarten Rollator – beim 57. Regionalwettbewerb wurden in Buch viele spannende Projekte…

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New insights: how potassium and sodium are conducted through ion channels

Tiny ion channels are responsible for transporting potassium and sodium to our cells. In the process, ions must pass through a bottleneck, referred to as the selectivity…

Structure of the ASOR channel

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Solving puzzles of the chloride ion channel ASOR

The chloride ion channel ASOR is found in almost all our cells. But apart from its involvement in cell death, not much is known about its physiological role. Two years ago,…

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Understanding the role of the largest organelle in nerve cells - Marijn Kuijpers receives 1.5 Million Euros of Funding from the European Research Council (ERC)

The prestigious Starting Grant from the European Research Council (ERC) was awarded to Dr. Marijn Kuijpers from the Leibniz-Forschungsinstitut für Molekulare Pharmakologie…

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A defective potassium channel disrupts the brain's navigation system.

The potassium channel KCNQ3 is required for our brain to generate accurate spatial maps. In mice, defects in KCNQ3 function have measurable effects on the internal…

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Large Molecules Transported into Living Cells: Researchers Achieve Breakthrough into Cell Interior

It is one of the big pharmacological questions: How do you get large functional biomolecules like proteins or antibodies into a living cell? Linking antibodies or proteins…

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Zukunftsfähige Ideen im Wettbewerb „Jugend forscht“

Das Immunsystem mit Kefirknollen stärken, intelligente Straßenmodelle entwickeln, ein Programm für chemische Reaktionen schreiben: Die Gewinner*innen des 56.…

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Disorientating dormant tumor cells

Chemotherapy is often unable to ensure adequate destruction of dormant cancer cells that have detached from the primary tumor and are circulating in the bloodstream. Sooner…

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Enhanced speed, contrast, and information: New contrast mechanism improves xenon MRI

Xenon magnetic resonance imaging offers deep insights into the human body and opens up new possibilities in the diagnosis and treatment of diseases. Physicists from the…

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Neuer Sonderforschungsbereich über Hydrogele an Grenzflächen und verlängerter SFB 1078, beide mit Beteiligung des FMP

Die Deutsche Forschungsgemeinschaft (DFG) hat einen Sonderforschungsbereich (SFB) neu bewilligt. Die Forschenden untersuchen anhand der Atemwege und des Darms Dynamische…

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CLCN6 identified as disease gene for a severe form of lysosomal neurodegenerative disease

A mutation in the CLCN6 gene is associated with a novel, particularly severe neurodegenerative disorder. Scientists from the Leibniz-Forschungsinstitut für Molekulare…

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Light shed on the atomic resolution structure of phage DNA tube – a methodological milestone

Given that phages are able to destroy bacteria, they are of particular interest to science. Basic researchers from the Leibniz-Forschungsinstitut für Molekulare…

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Christian Hackenberger receives breakthrough award in life sciences at the Berlin Science Week

Christian Hackenberger is honored at the Falling Walls conference with a “breakthrough of the year”-award in the life sciences. Ten scientific "breakthroughs of the year"…

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Surprising insights into the role of autophagy in neurons

It appears that autophagy protects our neurons in the brain, but evidently for entirely different reasons than previously assumed, as researchers from the…

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Fan Liu receives 1.5 Million Euros of Funding from the European Research Council (ERC)

Prof. Dr. Fan Liu from the Leibniz-Forschungsinstitut für Molekulare Pharmakologie (FMP) receives a prestigious ERC Starting Grant of the European Research Council (ERC).…

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FMP spin-off Tubulis acquires €10.7 million for the development of novel antibody drug conjugates (ADCs)

The young company Tubulis announced today the closure of a Series A funding round totaling €10.7 million to advance the development of a novel class of highly stable and…

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Understanding the Formation of Nerve Cell Contacts - Volker Haucke receives 2.5 Million Euros of Funding from the European Research Council (ERC)

Professor Volker Haucke from the Leibniz-Forschungsinstitut für Molekulare Pharmakologie (FMP) and the Freie Universität Berlin receives a prestigious ERC Advanced Grant of…

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How do we study signaling pathways within the cell?

>>>>>>>>>>>>>>>>NEW METHOD Proteins transmit signals in cells, whereby faulty signal transduction can lead to diseases such as cancer. Chemist Sandra Schlomach has…

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A Gentler, More Effective Cancer Treatment?

>>>>>>>>>>>>>>>LESS SIDE EFFECTS To effectively reach and eliminate tumor cells, a molecular transporter must deliver the cytotoxin with pinpoint accuracy. This can…

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Dynamic images show rhomboid protease in action

Rhomboid proteases are clinically relevant membrane proteins that play a key role in various diseases. Using solid-state NMR spectroscopy, researchers from Berlin’s…

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Bringing cancer medication safely to its destination

Treating cancer more selectively and more effectively – this could be achieved with an innovative technology developed by teams of researchers at the…

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Volker Haucke receives Feldberg Prize

Prof. Volker Haucke, Director at the Leibniz-Forschungsinstitut für Molekulare Pharmakologie (FMP) receives the Feldberg Prize 2020, which is awarded annually by the…

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Presynapses come in a packet – Berlin Scientists Identify the Components and Architecture of Neuronal Contact Sites

Synapses are the interfaces for information exchange between neurons. Teams of scientists working with Professor Dr. Volker Haucke, Director at the…