Publications 2011-2015

On this page

2015

71. C.P.R. Hackenberger, P.R. Chen

Curr. Opin. Chem. Biol. 2015, 28, VII-IX
Editorial overview: Synthetic biomolecules: Synthetic protein modifications - a giant leap towards understanding and generating biological functions
Link to the article

70. D. Schumacher, J. Helma, F.A. Mann, G. Pichler, F. Natale, E. Krause, M.C. Cardoso, C.P.R. Hackenberger, H. Leonhardt

Angew. Chem. Int. Ed. 2015, 54(46), 13787-13791
Versatile and Efficient Site-Specific Protein Functionalization by Tubulin Tyrosine Ligase
Link to the article

Angew. Chem. 2015, 127(46), 13992-13996
Vielseitige, effiziente und ortsspezifische Proteinfunktionalisierung durch das Enzym Tubulin-Tyrosin Ligase
Link to the article

TOC Versatile and Efficient Site-Specific Protein Functionalization by Tubulin Tyrosine Ligase

69. M. Lehmann, B. Gottschalk, D. Puchkov, P. Schmieder, S. Schwagerus, C.P.R. Hackenberger, V. Haucke, J. Schmoranzer

Angew. Chem. Int. Ed. 2015, 54(45), 13230-13235
Multicolor Caged dSTORM Resolves the Ultrastructure of Synaptic Vesicles in the Brain
Link to the article
Angew. Chem. 2015, 127(45), 13428-13433
Link to the article

TOC Multicolor Caged dSTORM Resolves the Ultrastructure of Synaptic Vesicles in the Brain

68. B. Kuropka, A. Witte, J. Sticht, N. Waldt, P. Majkut, C.P.R. Hackenberger, B. Schraven, E. Krause, S. Kliche, C. Freund

Mol. Cell. Proteomics 2015, 14(11), 2961-2972
Analysis of Phosphorylation-dependent Protein Interactions of Adhesion and Degranulation Promoting Adaptor Protein (ADAP) Reveals Novel Interaction Partners Required for Chemokine-directed T cell Migration
Link to the article

67. J. Bertran-Vicente, M. Schümann, C.P.R. Hackenberger, E. Krause

Anal. Chem. 2015, 87(14), 6990-6994
Gas-Phase Rearrangement in Lysine Phosphorylated Peptides During Electron-Transfer Dissociation Tandem Mass Spectrometry
Link to the article

TOC Gas-Phase Rearrangement in Lysine Phosphorylated Peptides During Electron-Transfer Dissociation Tandem Mass Spectrometry

66. M. Mühlberg, M. G. Hösl, C. Kühne, J. Dernedde, N. Budisa, C.P.R. Hackenberger

Beilstein JOC 2015, 11, 784-791
Orthogonal dual-modification of proteins for the engineering of multivalent protein scaffolds
Link to the article

TOC Orthogonal dual-modification of proteins for the engineering of multivalent protein scaffolds

65. J. Rosenlöcher, V. Böhrsch, M. Sacharjat, V. Blanchard, C. Giese, V. Sandig, C.P.R. Hackenberger, S. Hinderlich

Bioengineering 2015, 2, 213-234
Applying Acylated Fucose Analogues to Metabolic Glycoengineering
Link to the article

64. J. Bertran-Vicente, M. Schümann, P. Schmieder, E. Krause, C.P.R. Hackenberger

Org. Biomol. Chem. 2015, 13, 6839-6843
Direct access of site-specifically phosphorylated-lysine peptides from a solid-support
Link to the article
(The article is part of the themed collection: 2015 Hot Articles in Organic and Biomolecular Chemistry)

TOC Direct access of site-specifically phosphorylated-lysine peptides from a solid-support

63. D. Agrawal, C.P.R. Hackenberger

in "Chemistry of Organo-hybrids: Synthesis and Characterization of Functional Nano-Objects", Wiley, Bernadette Charleux, Christophe Coperet, Emmanuel Lacote (Eds) 2015
Chemoselective Protein Modifications: Methods and Applications for the Functionalization of Viral Capsids (book chapter)
Link to the book

62. C. Witte, V. Martos, H.M. Rose, S. Reinke, S. Klippel, L. Schröder, C.P.R. Hackenberger

Angew. Chem. Int. Ed. 2015, 54(9), 2806-2810 (VIP-Paper)
Live-cell MRI of Xenon Hyper-CEST Biosensors Targeted to Metabolically Labeled Cell-Surface Glycans
Link to the article

Angew. Chem. 2015, 127(9), 2848-2852
Xenon-MRT an lebenden Zellen mit Hyper-CEST-Biosensoren für metabolisch markierte Glykane an der Zelloberfläche
Link to the article

TOC Live-cell MRI of Xenon Hyper-CEST Biosensors Targeted to Metabolically Labeled Cell-Surface Glycans

61. N. Nischan, H.D. Herce, F. Natale, N. Bohlke, N. Budisa, M.C. Cardoso, C.P.R. Hackenberger

Angew. Chem. Int. Ed. 2015, 54(6), 1950-1953
Covalent Attachment of Cyclic TAT Peptides to GFP Results in Protein Delivery into Live Cells with Immediate Bioavailability
Link to the article

Angew. Chem. 2015, 127(6), 1972-1976
Kovalente Verknüpfung cyclischer TAT-Peptide mit GFP resultiert in der direkten Aufnahme in lebende Zellen mit sofortiger biologischer Verfügbarkeit
Link to the article

TOC Covalent Attachment of Cyclic TAT Peptides to GFP Results in Protein Delivery into Live Cells with Immediate Bioavailability

60. M.R.J. Vallée, P. Majkut, D. Krause, M. Gerrits, C.P.R. Hackenberger

Chem. Eur. J. 2015, 21(3), 970-974
Chemoselective Bioconjugation of Triazole Phosphonites in Aqueous Media
Link to the article

TOC Chemoselective Bioconjugation of Triazole Phosphonites in Aqueous Media

59. O. Reimann, C. Smet-Nocca, C.P.R. Hackenberger

Angew. Chem. Int. Ed. 2015, 54(1), 306-310
Traceless Purification and Desulfurization of Tau Protein Ligation Products
Link to the article

Angew. Chem. 2015, 127(1), 311-315
Spurlose Aufreinigung und Desulfurierung von Ligationsprodukten des Tau-Proteins
Link to the article

TOC Traceless Purification and Desulfurization of Tau Protein Ligation Products

58. O. Reimann, M. Glanz, C.P.R. Hackenberger

Bioorganic & Medicinal Chemistry 2015, 23(12), 2890-2894
Native chemical ligation between asparagine and valine: Application and limitations for the synthesis of tri-phosphorylated C-terminal tau
Link to the article

TOC Native chemical ligation between asparagine and valine: Application and limitations for the synthesis of tri-phosphorylated C-terminal tau

57. M. Schmitz, M. Kuhlmann, O. Reimann, C.P.R. Hackenberger, J. Groll

Biomacromolecules 2015, 16(4), 1088-1994
Side-Chain Cysteine-Functionalized Poly(2-oxazoline)s for Multiple Peptide Conjugation by Native Chemical Ligation
Link to the article

TOC Side-Chain Cysteine-Functionalized Poly(2-oxazoline)s for Multiple Peptide Conjugation by Native Chemical Ligation

56. M. Kuhlmann, O. Reimann, C.P.R. Hackenberger, J. Groll

Macromol. Rapid Commun. 2015, 36, 472
Cysteine-Functional Polymers via Thiol-ene Conjugation
Link to the article

TOC Cysteine-Functional Polymers via Thiol-ene Conjugation

2014

55. N. Nischan, C.P.R. Hackenberger

JOC 2014, 79(22), 10727-10733
Site-specific PEGylation of Proteins: Recent Developments
Link to the article

TOC Site-specific PEGylation of Proteins: Recent Developments

54. D. Schumacher, C.P.R. Hackenberger

Curr. Opin. Chem. Biol. 2014, 22, 62-69
More than add-on: chemoselective reactions for the synthesis of functional peptides and proteins
Link to the article

TOC More than add-on: chemoselective reactions for the synthesis of functional peptides and proteins

53. J. Bertran-Vicente, R.A. Serwa, M. Schümann, P. Schmieder, E. Krause, C.P.R. Hackenberger

J. Am Chem. Soc. 2014, 136(39), 13622-13628
Site-Specifically Phosphorylated Lysine Peptides
Link to the article

TOC Site-Specifically Phosphorylated Lysine Peptides

52. M. Mühlberg, K.D. Siebertz, B. Schlegel, P. Schmieder, C.P.R. Hackenberger

Chem. Commun. 2014, 50(35), 4603-4606
Controlled thioamide vs. amide formation in the thioacid-azide reaction under acidic aqueous conditions
Link to the article

TOC Controlled thioamide vs. amide formation in the thioacid-azide reaction under acidic aqueous conditions

51. C.F.W. Becker, A. Brik, P. Dawson, C.P.R. Hackenberger

J. Pept. Sci. 2014, 20, 63
Chemical protein synthesis
Link to the article

2013

50. P. Majkut, I. Claußnitzer, H. Merk, C. Freund, C.P.R. Hackenberger, M. Gerrits

PLoS ONE 2013, 8(12): e82352
Completion of Proteomic Data Sets by Kd Measurement Using Cell-Free Synthesis of Site-Specifically Labeled Proteins
Link to the article

49. N. Nischan, A. Chakrabarti, R.A. Serwa, P.H.M. Bovee-Geurts, R. Brock, C.P.R. Hackenberger

Angew. Chem. Int. Ed. 2013, 52(45), 11920-11924
Stabilization of Peptides for Intracellular Applications by Phosphoramidate-Linked Polyethylene Glycol Chains
Link to the article

Angew. Chem. 2013, 125(45), 12138-12142
Stabilisierung von Peptiden für intrazelluläre Anwendungen mit Phosphoramidat-verzweigten Polyethylenglycol-Ketten
Link to the article

TOC Stabilization of Peptides for Intracellular Applications by Phosphoramidate-Linked Polyethylene Glycol Chains

48. M.R.J. Vallée, L.M. Artner, J. Dernedde, C.P.R. Hackenberger

Angew. Chem. Int. Ed. 2013, 52, 9504-9508 (VIP Paper)
Alkyne Phosphonites for Sequential Azide-Azide Couplings
Link to the article

Angew. Chem. 2013, 125, 9682-9686 (VIP Paper)
Alkinphosphonite für sequenzielle Azid-Azid-Kupplungen
Link to the article

TOC Alkyne Phosphonites for Sequential Azide-Azide Couplings

47. J. Bertran-Vicente, C.P.R. Hackenberger

Angew. Chem. Int. Ed. 2013, 52(24), 6140-6142
A Supramolecular Peptide Synthesizer (Highlight)
Link to the article

Angew. Chem. 2013, 125(24), 6256-6258
Ein supramolekularer Peptidsynthesizer (Highlight)
Link to the article

TOC A Supramolecular Peptide Synthesizer

46. S. Sowa, M. Mühlberg, K.M. Pietrusiewicz, C.P.R. Hackenberger

Bioorg. Med. Chem. 2013, 21, 3465-3472
Traceless Staudinger acetylation of azides in aqueous buffers
Link to the article

TOC Traceless Staudinger acetylation of azides in aqueous buffers

45. D. Agrawal, C.P.R. Hackenberger

Indian J. Chem. 2013, 52A, 973-991
Site-specific chemical modifications of proteins

2012

44. V. Böhrsch, T. Mathew, M. Zieringer, M.R.J. Vallée, L.M. Artner, J. Dernedde, R. Haag, C.P.R. Hackenberger

Org. Biomol. Chem. 2012, 10, 6211-6216
Chemoselective Staudinger-phosphite reaction of symmetrical glycosyl-phosphites with azido-peptides and polygycerols
(10-year-anniversairy issue of Org. Biomol. Chem.)
Link to the article

TOC Chemoselective Staudinger-phosphite reaction of symmetrical glycosyl-phosphites with azido-peptides and polygycerols

43. H. Möller, V. Böhrsch, J. Bentrop, J. Bender. S. Hinderlich, C.P.R. Hackenberger

Angew. Chem. Int. Ed. 2012, 51(24), 5986-5990
Glycan-Specific Metabolic Oligosaccharide Engineering of C7-Substituted Sialic Acids
Link to the article

Angew. Chem. 2012, 124(24), 6088-6092
Glycan-spezifisches metabolisches Oligosaccharid-Engineering von C7-substituierten Sialinsäuren
Link to the article

TOC Glycan-Specific Metabolic Oligosaccharide Engineering of C7-Substituted Sialic Acids
Glycan-Specific Metabolic Oligosaccharide Engineering of C7-Substituted Sialic Acids

42. M. Broncel, E. Krause, D. Schwarzer, C.P.R. Hackenberger

Chem. Eur. J. 2012, 18, 2488-2492
The Alzheimer's Disease Related Tau Protein as a New Target for Chemical Protein Engineering (selected as VIP-paper)
Link to the article

TOC The Alzheimer's Disease Related Tau Protein as a New Target for Chemical Protein Engineering

41. L.M. Artner, L. Merkel, N. Bohlke, F. Beceren-Braun, C. Weise, J. Dernedde, N. Budisa, C.P.R. Hackenberger

Chem. Commun. 2012, 48, 522-524
Site-selective modification of proteins for the synthesis of structurally defined multivalent scaffolds
Link to the article

TOC Site-selective modification of proteins for the synthesis of structurally defined multivalent scaffolds

2011

40. M.R.J. Vallée, P. Majkut, I. Wilkening, C. Weise, G. Müller, C.P.R. Hackenberger

Org. Lett. 2011, 13, 5440-5443
Staudinger-Phosphonite Reactions for the Chemoselective Transformation of Azido-Containing Peptides and Proteins
Link to the article

TOC Staudinger-Phosphonite Reactions for the Chemoselective Transformation of Azido-Containing Peptides and Proteins

39. I. Wilkening, G. del Signore, W. Ahlbrecht, C.P.R. Hackenberger

Synthesis 2011, 17, 2709-2720
Lewis Acid or Alkyl Halide Promoted Rearrangements of Phosphor- and Phosphinimidates to N,N-Disubstituted Phosphor- and Phosphinamidates (Feature Article)
Link to the article

TOC Lewis Acid or Alkyl Halide Promoted Rearrangements of Phosphor- and Phosphinimidates to N,N-Disubstituted Phosphor- and Phosphinamidates

38. H. Möller, V. Böhrsch, C.P.R. Hackenberger, S. Hinderlich

J. Carb. Chem. 2011, 4-6, 334-346
N-Azidoacetylomannosamine and N-Azidoacetylgalactosamine Incorporation into N-Glycans of Recombinantly Expressed Human Lactotransferrin by Metabolic Oligosaccharide Engineering
Link to the article

37. H. Möller, V. Böhrsch, L. Lucka, C.P.R. Hackenberger, S. Hinderlich

Mol. Biosyst. 2011, 7, 2245-2251
Efficient metabolic oligosaccharide engineering of glycoproteins by UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase (GNE) knock-down
Link to the article

36. P. Majkut, V. Böhrsch, R. Serwa, M. Gerrits, C.P.R. Hackenberger

in "Methods in Molecular Biology, Vol. 794: Unnatural Amino Acids", Springer, Loredano Pollegioni, Stefano Servi (eds) 2011
Site-Specific Modification of Proteins by the Staudinger-Phosphite Reaction (Book chapter)
Link to the article

35. C. Smet-Nocca, M. Broncel, J.-M. Wieruszeski, C. Tokarski, X. Hanoulle, A. Leroy, I. Landieu, C. Rolando, G. Lippens, C.P.R. Hackenberger

Mol. Biosyst. 2011, 7, 1420-1429
Identification of O-GlcNAc sites within peptides of the Tau protein and their impact on phosphorylation
Link to the article

TOC Identification of O-GlcNAc sites within peptides of the Tau protein and their impact on phosphorylation

34. I. Wilkening, G. del Signore, C.P.R. Hackenberger

Chem. Commun. 2011, 47, 349-351
Synthesis of phosphonamidate peptides by Staudinger reactions of silylated phosphinic acids and esters
Emerging Investigator Issue
Link to the article

TOC Synthesis of phosphonamidate peptides by Staudinger reactions of silylated phosphinic acids and esters Emerging Investigator Issue