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Our work embraces peptides, proteins and low molecular weight drug-like molecules, along with the further development of protein analytics, conjugation and delivery techniques. Biochemical, computational and physical methods aid to investigate interactions of substances with important protein structures. High-throughput screening approaches enable the identification of small molecules and the regulation of gene expression at the cellular, pathway, and molecular levels.
Thereby we contribute to a central goal of the institute which is the elucidation of new principles for pharmacological intervention, which may ultimately lead to novel diagnostic and disease treatment strategies.
Group(s)
Dorothea Fiedler
Chemical Biology of Signal Transduction
Our group seeks to develop a better understanding of the multiple ways in which nature utilizes phosphate in both protein signaling cascades…
Research UnitChristian Hackenberger
Biomolecule Modification and Delivery
Our group is interested in understanding how nature generates specific biological function in complex cellular environments. Research…
Research UnitHan Sun
Structural Chemistry and Computational Biophysics
Our group studies the structure of drug-like molecules and characterizes their interactions with proteins. We apply a variety of…
Research UnitMarc Nazaré
Medicinal Chemistry
Our group is focused on developing new chemical tools to answer fundamental biological questions. These tools cover a broad range of…
Research GroupJohannes Broichhagen
ChemBioProbes
Our lab is looking for new ways to visualize and interrogate biological function, such as cell signalling or protein dynamics.
Junior GroupChristian Hackenberger
Peptide Chemistry
The core facility aims at providing simple synthetic peptides to FMP research groups.
Core FacilityJens Peter von Kries
Screening Unit
The Screening Unit provides an open access high throughput technology platform for screening compound libraries (170.000 drug like…
Core FacilityEdgar Specker
Compound Management
The aim of the Core Facility Compound Mangement is the production of screening plates for the primary screening at the Screening Unit, the…
Core Facility