Chemical Biology

Chemical Biology investigates the function of biological systems with the means of chemical synthesis. The research of this section focuses on the discovery, synthesis and use of chemical tools that can modulate specifically and selectively the function of target proteins.

This work embraces peptides, proteins and low molecular weight drug-like molecules as well as the further development of protein analytics by mass spectroscopy. Biochemical and physical methods aid to investigate interactions of substances with important protein structures. Thereby we support a central goal of the institute which is the elucidation of new principles for pharmacological intervention with biological processes that may ultimately lead to new treatments of diseases.

Scientific Coordinator

 Group(s)

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Dorothea Fiedler

Chemical Biology of Signal Transduction

Our group seeks to develop a better understanding of the multiple ways in which nature utilizes phosphate in both protein signaling cascades…

Department
DepartmentChemical Biology

Christian Hackenberger

Chemical Biology II

Our group is interested in understanding how nature generates specific biological function in complex cellular environments. Research…

Department
DepartmentChemical Biology

Marc Nazaré

Medicinal Chemistry

Our group is focused on developing new chemical tools to answer fundamental biological questions. These tools cover a broad range of…

Research Group
Research GroupChemical Biology

Han Sun

Structural Chemistry and Computational Biophysics

Our group studies the structure of drug-like molecules and characterizes their interactions with proteins. We apply a variety of…

Research Group
Research GroupChemical Biology

Johannes Broichhagen

ChemBioProbes

Our lab is looking for new ways to visualize and interrogate biological function, such as cell signalling or protein dynamics.

Junior Group
Junior GroupChemical Biology

Christian Hackenberger

Peptide Chemistry

The core facility aims at providing simple synthetic peptides to FMP research groups.

Core Facility
Core FacilityChemical Biology

Jens Peter von Kries

Screening Unit

The Screening Unit provides a high throughput technology platform for screening compound libraries (about 60.000 cpds) and for genome-wide…

Core Facility
Core FacilityChemical Biology

Edgar Specker

Compound Management

The aim of the Core Facility Compound Mangement is the production of screening plates for the primary screening at the Screening Unit, the…

Core Facility
Core FacilityChemical Biology