Dr.

David Furkert

PhD student 2017 – 2022  |  Current position: Postdoc at Novartis, Basel

@david-furkert-373564146

0000-0002-6145-5397

Publications

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2023 2022 2021 2020 2017
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Itraconazole inhibits endothelial cell migration by disrupting inositol pyrophosphate-dependent focal adhesion dynamics and cytoskeletal remodeling

  • Ji Qi; Weiwei Cheng; Zhe Gao; Yuanyuan Chen; Megan L. Shipton; David Furkert; Alfred C. Chin; Andrew M. Riley; Dorothea Fiedler; Barry V.L. Potter; Chenglai Fu

Biomedicine & Pharmacotherapy 2023

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Versatile signaling mechanisms of inositol pyrophosphates

  • Minh Nguyen Trung; David Furkert; Dorothea Fiedler

Current Opinion in Chemical Biology 2022

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Dissecting the activation of insulin degrading enzyme by inositol pyrophosphates and their bisphosphonate analogs

  • Sarah Hostachy; Tillmann Utesch; Katy Franke; Gillian Leigh Dornan; David Furkert; Berke Türkaydin; Volker Haucke; Han Sun; Dorothea Fiedler

Chemical Science 2021

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Affinity enrichment and identification of inositol poly- and pyrophosphate interactomes

  • David Furkert

STAR Protocols 2021

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Using Biotinylated myo-Inositol Hexakisphosphate to Investigate Inositol Pyrophosphate–Protein Interactions with Surface-Based Biosensors

  • David Furkert

Biochemistry 2021

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Structural evidence for visual arrestin priming via complexation of phosphoinositols

  • David Furkert

Structure 2021

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IP7-SPX Domain Interaction Controls Fungal Virulence by Stabilizing Phosphate Signaling Machinery

  • David Furkert

mBio 2020

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Triplexed Affinity Reagents to Sample the Mammalian Inositol Pyrophosphate Interactome

  • David Furkert; Sarah Hostachy; Michal Nadler-Holly; Dorothea Fiedler

Cell Chemical Biology 2020

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The inositol pyrophosphate 5-InsP 7 drives sodium-potassium pump degradation by relieving an autoinhibitory domain of PI3K p85α

  • Alfred C. Chin; Zhe Gao; Andrew M. Riley; David Furkert; Christopher Wittwer; Amit Dutta; Tomas Rojas; Evan R. Semenza; Robin A. Felder; Jennifer L. Pluznick; Henning J. Jessen; Dorothea Fiedler; Barry V. L. Potter; Solomon H. Snyder; Chenglai Fu

Science Advances 2020

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Amplification of a FRET Probe by Lipid-Water Partition for the Detection of Acid Sphingomyelinase in Live Cells

  • David Furkert

Angewandte Chemie International Edition 2017

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