Peter Schmieder

NMR

Nuclear Magnetic Resonance Spectroscopy (NMR): The NMR facility maintains FMP’s NMR spectrometers, enabling internal and external researchers to use both solid-state and solution-state NMR spectroscopy.
NMR spectroscopy allows us to study the electronic environment of individual atoms and their interactions with neighboring atoms, for example to determine the structure and dynamics of molecules. Our facility provides the research groups with two open-access spectrometers (300 MHz and 600 MHz) for their own use. For more complex problems, we collaborate with the scientists using our NMR instruments equipped with cryoprobes. A probe suitable for ³¹P-NMR spectroscopy is of particular importance because the phosphorylation of different molecules is studied intensively in the Chemical Biology departments.
The solid-state spectrometers are primarily used by the Structural Biology departments to determine the structures of membrane proteins or larger aggregates. For this purpose, a wide range of field strengths and probes with different sample diameters is used. DNP (dynamic nuclear polarization) experiments can also be performed on two spectrometers. Furthermore, the facility receives requests from groups outside of the FMP, as well as from commercial companies located close to the institute. These requests are met in the form of collaborative activities or as a NMR service provided by the facility. The NMR facility also participates in the German DFG-funded G-NMR network of facilities, the iNEXT initiative, and worldwide NMR studies such as the Fab-NMR study by NIST.

Contact

Dr. Peter Schmieder

Head, NMR,
Head Works Council

+49 30 94793 227
schmieder@fmp-berlin.de

Research Section

Structural Biology

Research Projects

Determination of pKa-Values by NMR with Anett Hauser, Lisa Gerland, Christian Hackenberger, Hartmut Oschkinat

Hunting the eagel killer with Steffen Breinlinger, Timo Niedermeyer

NMR investigation of photochromic compounds with Johannes Broichhagen

Halogen–Aryl-Pi Interactions from Molecular Torsion Balances with Han Sun, Mark Nazare

Determination of pKa-Values by NMR with Anett Hauser, Lisa Gerland, Christian Hackenberger, Hartmut Oschkinat

NMR investigation of the sialyl-pathway with Jakob Gorenflos, Christian Hackenberger

Head

About Peter Schmieder

Peter Schmieder was born in 1963 in Frankfurt/Main, Germany. He studied chemistry at the Johann-Wolfgang-Goethe University in Frankfurt, where he obtained his diploma under the supervision of Horst Kessler in 1988. He then moved to the TU Munich together with Prof. Kessler and finished his Ph.D. in 1991. In 1992 he changed to the Department of BCMP at Harvard Medical School and worked with Gerhard Wagner until 1995. In 1995 he became group leader of the NMR-group in the department of NMR-assisted structural biology at the FMP in Berlin, the group was later on named "AG Solution State NMR". His research interests are the development of new NMR-spectroscopic techniques, the structure elucidation of all kinds of molecular systems and the study of their dynamic properties.

Teaching

Teaching
Find lecture notes

Publications

Publications
Here you will find the list of publications

NMR Facility

NMR facility links

nmr facility picture galleries

fmp600

delivered in 1995, purchased with funds from the FMP
new hardware cabinet in 2012

Magnet

Bruker, unshielded, 52 mm bore

Hardware

AV III Console
sample changer (BACS-60)

Probes

5 mm QXI, z-gradient
5mm BBFO, z-Gradient
5 mm TXI, xyz-gradients
5 mm BBI, z-gradient
8 mm TXI, z-gradient

psf600

delivered in 1999 as DRX, purchased with funds from the BMBF
upgraded to AV in 2010, cryoplattform replacement in 2011

Magnet

Bruker, shielded, 54 mm bore

Hardware

AV III Console
sample changer (BACS 60)

Probes

5 mm TXI, z-gradient
5 mm QCI Cryoprobe, z-gradient

sel600

delivered in 2008, purchased with funds from the FMP

Magnet

Bruker, shielded plus, 54 mm bore

Hardware

AV III Console
sample changer (BACS 60)

Probes

5 mm TCI Cryoprobe, z-grandient

fmp750

delivered in 1996 as a DMX, purchased with funds from the FMP
upgraded to AV in 2007

Magnet

Magnex, unshielded, 52 mm bore

Hardware

AV III Console

Probes

5 mm TXI, xyz-gradients
8 mm TXI, z-gradient
5 mm TCI Cryoprobe, z-grandient

av300

delivered in 2005, purchased with funds from the FMP, new hardware cabinet in 2016

Magnet

Bruker, shielded, 54 mm bore

Hardware

AVIII Console
sample changer (BACS 120)

Probes

5 mm QNP (13C, 19F, 31P), z-gradient
5mm BBFO, z-Gradient

fmp600

delivered in 1995, purchased with funds from the FMP
new hardware cabinet in 2012

Magnet

Bruker, unshielded, 52 mm bore

Hardware

AV III Console
sample changer (BACS-60)

Probes

5 mm QXI, z-gradient
5mm BBFO, z-Gradient
5 mm TXI, xyz-gradients
5 mm BBI, z-gradient
8 mm TXI, z-gradient

psf600

delivered in 1999 as DRX, purchased with funds from the BMBF
upgraded to AV in 2010, cryoplattform replacement in 2011

Magnet

Bruker, shielded, 54 mm bore

Hardware

AV III Console
sample changer (BACS 60)

Probes

5 mm TXI, z-gradient
5 mm QCI Cryoprobe, z-gradient

sel600

delivered in 2008, purchased with funds from the FMP

Magnet

Bruker, shielded plus, 54 mm bore

Hardware

AV III Console
sample changer (BACS 60)

Probes

5 mm TCI Cryoprobe, z-grandient

fmp750

delivered in 1996 as a DMX, purchased with funds from the FMP
upgraded to AV in 2007

Magnet

Magnex, unshielded, 52 mm bore

Hardware

AV III Console

Probes

5 mm TXI, xyz-gradients
8 mm TXI, z-gradient
5 mm TCI Cryoprobe, z-grandient

av300

delivered in 2005, purchased with funds from the FMP, new hardware cabinet in 2016

Magnet

Bruker, shielded, 54 mm bore

Hardware

AVIII Console
sample changer (BACS 120)

Probes

5 mm QNP (13C, 19F, 31P), z-gradient
5mm BBFO, z-Gradient

dnp400

delivered in 2007, purchased with funds from the FMP, moved in 2008
upgraded with Gyrotron to enable DNP in 2009

Magnet

Bruker, shielded, 89 mm bore (switched to magnet from other 400 WB in 2008)

Hardware

AV III Console

Probes

2.5 mm MAS HXY
3.2 mm MAS HXY
3.2 mm MAS HXY (Low-T for DNP)
4.0 mm MAS HXY

av600

delivered in 2003, purchased with funds from the BMBF and the FMP

Magnet

Bruker, shielded, 89 mm bore

Hardware

AV III Console

Probes

1.3 mm MAS HXY
1.9 mm MAS HXY
3.2 mm MAS HXY
4.0 mm MAS HXY

av700

delivered in 2005, purchased with funds from the the FMP

Magnet

Bruker, shielded plus, 89 mm bore

Hardware

AV NEO Console

Probes

1.9 mm MAS HCND
3.2 mm MAS HXY
3.2 mm MAS HCN (Efree)
4.0 mm MAS HXY

av800

delivered in 2013, purchased with funds from the FMP upgraded with Gyrotron to enable DNP in 2019

Magnet

Bruker, shielded plus, 89 mm bore

Hardware

AV III Console

Probes

1.3 mm MAS HCND
1.9 mm MAS HXY (Low-T for DNP)
3.2 mm MAS HCN (Efree)
4.0 mm MAS HCN (Efree)

av900

delivered in 2004, purchased with funds from the BMBF and the city of Berlin

Magnet

Bruker, unshielded, 54 mm bore

Hardware

AV NEO Console

Probes

5 mm TXI, z-gradient
1.3 mm MAS (VTX) HCND
1.9 mm MAS HCND
3.2 mm MAS HCN
4.0 mm MAS HCN

dnp400

delivered in 2007, purchased with funds from the FMP, moved in 2008
upgraded with Gyrotron to enable DNP in 2009

Magnet

Bruker, shielded, 89 mm bore (switched to magnet from other 400 WB in 2008)

Hardware

AV III Console

Probes

2.5 mm MAS HXY
3.2 mm MAS HXY
3.2 mm MAS HXY (Low-T for DNP)
4.0 mm MAS HXY

av600

delivered in 2003, purchased with funds from the BMBF and the FMP

Magnet

Bruker, shielded, 89 mm bore

Hardware

AV III Console

Probes

1.3 mm MAS HXY
1.9 mm MAS HXY
3.2 mm MAS HXY
4.0 mm MAS HXY

av700

delivered in 2005, purchased with funds from the the FMP

Magnet

Bruker, shielded plus, 89 mm bore

Hardware

AV NEO Console

Probes

1.9 mm MAS HCND
3.2 mm MAS HXY
3.2 mm MAS HCN (Efree)
4.0 mm MAS HXY

av800

delivered in 2013, purchased with funds from the FMP upgraded with Gyrotron to enable DNP in 2019

Magnet

Bruker, shielded plus, 89 mm bore

Hardware

AV III Console

Probes

1.3 mm MAS HCND
1.9 mm MAS HXY (Low-T for DNP)
3.2 mm MAS HCN (Efree)
4.0 mm MAS HCN (Efree)

av900

delivered in 2004, purchased with funds from the BMBF and the city of Berlin

Magnet

Bruker, unshielded, 54 mm bore

Hardware

AV NEO Console

Probes

5 mm TXI, z-gradient
1.3 mm MAS (VTX) HCND
1.9 mm MAS HCND
3.2 mm MAS HCN
4.0 mm MAS HCN

NMR Facility Buildings

FMP and NMR buildings

NMR1 building for solution NMR spectrometer

Plan of NMR1 with magnetic fields

NMR2 building for solid state NMR spectrometer

Plan of NMR2 with magnetic fields

Campus plan

new magnet builing NMR3 still under construction

Group Members

This text and the images are published under the Creative Commons licence "CC BY-NC-ND 4.0 EN - Attribution-Non-Commercial-No Derivative Works 4.0 Germany". Author: Peter Schmieder for leibniz-fmp.de

You may share the text by mentioning the licence CC BY-NC-ND 4.0 DE and the author(s). Copyright information on images/graphics/videos can be found directly with the images and additionally in the appendix.