Marc Nazaré

Marc Nazare studied chemistry at the University of Karlsruhe and obtained his PhD in organic chemistry with Herbert Waldmann in the field of natural product total synthesis in 1999. He then joined pharmaceutical industry at Sanofi in Frankfurt as a medicinal chemist. In 2013, Dr. Nazaré started a medicinal chemistry group at the Leibniz Research Institute for Molecular Pharmacology FMP. His current research interests are focused on the design and optimization of chemical probes and imaging tools for chemical biology and translational applications.

Dr. Anahid Omran obtained her Bachelor and Master Degrees in Chemistry with a focus on organic synthesis. Afterwards she proceeded to strive into the field of medicinal chemistry to obtain a second Master’s degree from the Southern Illinois University Edwardsville. Focusing her research on the investigation of GPCRs, she received her doctorate from the Friedrich-Alexander University Erlangen, Germany in the group of Prof. Peter Gmeiner. She is currently developing chemical probes for the elucidation of GPCR functions at the Leibniz Research Institute for Molecular Pharmacology as a postdoctoral researcher under supervision of Dr. Marc Nazaré.   

Carolina completed both her BSc and MSc degree in Medicinal Chemistry at the University of Coimbra, focusing on organic chemistry.  She proceeded to PhD in the same area, joined a program that involved the Universities of Coimbra and Lisbon, in consortium with three Portuguese pharmaceutical companies (Bial, Bluepharma and Hovione). where she worked on new antimicrobial chemical entities, contributing to the challenging problem of antimicrobial resistant. She had also the opportunity to work in different laboratories (Lisbon, Poland and Brazil). In 2020, She joined the FMP for a postdoc and is currently working on the development of probes for detecting infections (bacteria or virus), on novel tankyrase inhibitors and in the research of cross-linkers for pediatric cardiac valves, a project in collaboration with GrOwValve©. 

Davide got his MSc degree in pharmaceutical chemistry and technology at the university of Milan where he also received his pharmacy certificate. He did his master thesis project in a collaboration between the De Amici`s group at the University of Milan and the Holzgrabe’s group at the university of Würzburg focusing on the development of hybrid ligands for the M1 muscarinic receptor. His PhD at the University of Bergen in the Bjørsvik`s group was funded by the European Commision under the H2020 – MSCA – ITN – 2015 programme (PET3D). As a part of this project, he had also the chance of an industrial secondment at AstraZeneca. During these three years, he mainly focused on the development of XCT inhbitors for cancer treatment and on method development for the functionalisation of imidazoles. In 2020, he joined Dr. Marc Nazaré’s group at the FMP and he is working mainly on the development of selective inhibitors for understudied kinases of biomedicial interest.

Ziqiong studied Pharmaceutical Engineering at Yunnan University where she got her Bachelor’s. She finished her master thesis in Shanghai Institute of Materia Medica (SIMM), University of Chinese Academy of Sciences where she mainly focused on the design of novel neuroactive steroids. Then she worked as a research assistant in SIMM and did research about transition metal catalysis. She joined the Medicinal Chemistry group at FMP in 2022 as a PhD student to investigate novel inhibitors.

Victoria studied chemistry at the University of Vienna for her bachelor’s degree, before pursuing a Master’s degree in Drug Discovery and Development. Her master thesis was written at Boehringer Ingelheim in the Medicinal Chemistry department, focusing on developing an enantioselective way to build up spiro-oxindoles. After her studies, she worked as an analytical chemist in a COVID lab, before moving to Basel for a year and taking part in the Roche internship in Medicinal Chemistry (RiCH) program. Victoria joined the research group of Dr. Marc Nazaré at the Leibniz Research Institute for Molecular Pharmacology in October 2022.

Marta studied pharmaceutical chemistry and technology at the university of Milano where she also received her pharmacy certificate. She did her master thesis at the group of Ulrike Holzgrabe at the university of Würzburg where she focused on the design of muscarinic allosteric modulators. She joined the medicinal chemistry group at the FMP in the beginning of 2022 as a PhD student to investigate novel inhibitor scaffolds.

Nina-Louisa Efrém holds a Bachelor’s degree in Biochemistry from Freie Universität Berlin. She obtained her Master’s degree in Drug Design and Synthesis from Vrije Universiteit Amsterdam. After her studies, she participated in the Roche internship in Medicinal Chemistry (RiCH) program in Basel, Switzerland. Nina-Louisa joined the Medicinal Chemistry research group at the Leibniz Institute for Molecular Pharmacology as a PhD student in October 2021. Her projects focus on the development of tool compounds for SHP2 and for C-type lectin receptors. She is an Early-Stage Researcher within the Marie Skłodowska-Curie innovative training network ALLOstery in Drug Discovery (ALLODD).

Machoud got his bachelors degree in pharmaceutical sciences at Paris Descartes university between 2014 and 2017. After graduating as a pharmacist, he pursued with a masters degree in molecular chemistry at Sorbonne university in 2020. He did his Master thesis in the group of Prof. Dr. Craig Crews at Yale university followed by a one year industrial placement in the medicinal chemistry department at Roche in Basel before joining our group in 2021.

Axel studied biomedicinal Chemistry at the Johannes-Gutenberg University Mainz where he obtained his masters degree in 2020. He joined the Nazaré lab in the same year as a doctoral student. He is interested in drug design and synthesis and currently working on chemical probes and tool compounds for biomedicinal research.

Leonard works as PhD student in the research group of Dr. Marc Nazaré at the FMP Berlin since 2019. His research area focuses on the development of fluorescent probes in an interdisciplinary environment with collaboration partners from chemistry, biology and industry. Before pursuing a PhD, he studied „Molecular Life Science“ at the Friedrich-Alexander-University Erlangen-Nürnberg where he completed his Bachelor’s and Master’s thesis in the field of cancer-cell specific prodrugs and reactive oxygen species in the group of Prof. Andriy Mokhir. In his free time he is interested in everything around bicycles.