Hartmut Oschkinat

NMR quality control of fragment libraries for screening.

• Hartmut Oschkinat

Journal of biomolecular NMR 2020

MAS NMR detection of hydrogen bonds for protein secondary structure characterization.

• Hartmut Oschkinat

Journal of biomolecular NMR 2020

Crystal structure of Q4D6Q6, a conserved kinetoplastid-specific protein from Trypanosoma cruzi.

• Hartmut Oschkinat

Journal of structural biology 2020

Collective exchange processes reveal an active site proton cage in bacteriorhodopsin.

• Hartmut Oschkinat

Communications biology 2020

pH-Dependent Protonation of Surface Carboxylate Groups in PsbO Enables Local Buffering and Triggers Structural Changes.

• Hartmut Oschkinat

Chembiochem : a European journal of chemical biology 2020

Innentitelbild: Pigmentierungschemie und radikalbasierter Kollagenabbau bei Alkaptonurie und Arthrose (Angew. Chem. 29/2020)

• Wing Ying Chow; Brendan P. Norman; Norman B. Roberts; Lakshminarayan R. Ranganath; Christian Teutloff; Robert Bittl; Melinda J. Duer; James A. Gallagher; Hartmut Oschkinat

Angewandte Chemie 2020

Pigmentation Chemistry and Radical‐Based Collagen Degradation in Alkaptonuria and Osteoarthritic Cartilage

• Wing Ying Chow; Brendan P. Norman; Norman B. Roberts; Lakshminarayan R. Ranganath; Christian Teutloff; Robert Bittl; Melinda J. Duer; James A. Gallagher; Hartmut Oschkinat

Angewandte Chemie International Edition 2020

Pigmentierungschemie und radikalbasierter Kollagenabbau bei Alkaptonurie und Arthrose

• Wing Ying Chow; Brendan P. Norman; Norman B. Roberts; Lakshminarayan R. Ranganath; Christian Teutloff; Robert Bittl; Melinda J. Duer; James A. Gallagher; Hartmut Oschkinat

Angewandte Chemie 2020

Inside Cover: Pigmentation Chemistry and Radical‐Based Collagen Degradation in Alkaptonuria and Osteoarthritic Cartilage (Angew. Chem. Int. Ed. 29/2020)

• Wing Ying Chow; Brendan P. Norman; Norman B. Roberts; Lakshminarayan R. Ranganath; Christian Teutloff; Robert Bittl; Melinda J. Duer; James A. Gallagher; Hartmut Oschkinat

Angewandte Chemie International Edition 2020

Host monitoring of quorum sensing during Pseudomonas aeruginosa infection.

• Hartmut Oschkinat

Science (New York, N.Y.) 2019

Protein resonance assignment by BSH-CP-based 3D solid-state NMR experiments: A practical guide.

• Hartmut Oschkinat

Magnetic resonance in chemistry : MRC 2019

Poly(ADP-Ribose) Links the DNA Damage Response and Biomineralization.

• Hartmut Oschkinat

Cell reports 2019

Dynamic Nuclear Polarization Magic-Angle Spinning Nuclear Magnetic Resonance Combined with Molecular Dynamics Simulations Permits Detection of Order and Disorder in Viral Assemblies.

• Hartmut Oschkinat

The journal of physical chemistry. B 2019

The companion of cellulose synthase 1 confers salt tolerance through a Tau-like mechanism in plants.

• Hartmut Oschkinat

Nature communications 2019

Detection of nucleic acids and other low abundance components in native bone and osteosarcoma extracellular matrix by isotope enrichment and DNP-enhanced NMR

• Hartmut Oschkinat

RSC Advances 2019

Structural changes of TasA in biofilm formation of Bacillus subtilis.

• Hartmut Oschkinat

Proceedings of the National Academy of Sciences of the United States of America 2018

Essential but sparse collagen hydroxylysyl post-translational modifications detected by DNP NMR.

• Hartmut Oschkinat

Chemical communications (Cambridge, England) 2018

RIP2 filament formation is required for NOD2 dependent NF-κB signalling.

• Hartmut Oschkinat

Nature communications 2018

DNP NMR of biomolecular assemblies.

• Hartmut Oschkinat

Journal of structural biology 2018

iNEXT: a European facility network to stimulate translational structural biology.

• Hartmut Oschkinat

FEBS letters 2018

The protofilament architecture of a de novo designed coiled coil-based amyloidogenic peptide.

• Hartmut Oschkinat

Journal of structural biology 2018

Efficiency of Water-Soluble Nitroxide Biradicals for Dynamic Nuclear Polarization in Rotating Solids at 9.4 T: bcTol-M and cyolyl-TOTAPOL as New Polarizing Agents.

• Hartmut Oschkinat

Chemistry (Weinheim an der Bergstrasse, Germany) 2018

Insight into small molecule binding to the neonatal Fc receptor by X-ray crystallography and 100 kHz magic-angle-spinning NMR.

• Hartmut Oschkinat

PLoS biology 2018

Understanding the roles of functional peptides in designing apatite and silica nanomaterials biomimetically using NMR techniques

• Hartmut Oschkinat

Current Opinion in Colloid & Interface Science 2018

Structural insight into protein-aided bacterial biofilm formation

• Hartmut Oschkinat

Acta Crystallographica Section A Foundations and Advances 2018

Dynamic Nuclear Polarization Enhanced MAS NMR Spectroscopy for Structural Analysis of HIV-1 Protein Assemblies.

• Hartmut Oschkinat

The journal of physical chemistry. B 2016

Studying the Conformation of a Silaffin-Derived Pentalysine Peptide Embedded in Bioinspired Silica using Solution and Dynamic Nuclear Polarization Magic-Angle Spinning NMR.

• Hartmut Oschkinat

Journal of the American Chemical Society 2016

bcTol : a highly water-soluble biradical for efficient dynamic nuclear polarization of biomolecules.

• Hartmut Oschkinat

Chemical communications (Cambridge, England) 2016

Structural basis for the dissociation of α-synuclein fibrils triggered by pressure perturbation of the hydrophobic core.

• Hartmut Oschkinat

Scientific reports 2016

Dynamic Nuclear Polarization Provides New Insights into Chromophore Structure in Phytochrome Photoreceptors.

• Hartmut Oschkinat

Angewandte Chemie (International ed. in English) 2016

Temperature dependence of cross-effect dynamic nuclear polarization in rotating solids: advantages of elevated temperatures.

• Hartmut Oschkinat

Physical chemistry chemical physics : PCCP 2016

Structural analysis of a signal peptide inside the ribosome tunnel by DNP MAS NMR.

• Hartmut Oschkinat

Science advances 2016

Multifunctional Benzoxazines Feature Low Polymerization Temperature and Diverse Polymer Structures.

• Hartmut Oschkinat

Polymers 2016

On The Potential of Dynamic Nuclear Polarization Enhanced Diamonds in Solid-State and Dissolution (13) C NMR Spectroscopy.

• Hartmut Oschkinat

Chemphyschem : a European journal of chemical physics and physical chemistry 2016

Chemical shift assignments and secondary structure prediction for Q4DY78, a conserved kinetoplastid-specific protein from Trypanosoma cruzi.

• Hartmut Oschkinat

Biomolecular NMR assignments 2016

Quantitative and Qualitative Analysis of Surface Modified Cellulose Utilizing TGA-MS.

• Hartmut Oschkinat

Materials (Basel, Switzerland) 2016

Surface Binding of TOTAPOL Assists Structural Investigations of Amyloid Fibrils by Dynamic Nuclear Polarization NMR Spectroscopy.

• Hartmut Oschkinat

Chembiochem : a European journal of chemical biology 2016

Structural biology applications of solid state MAS DNP NMR.

• Hartmut Oschkinat

Journal of magnetic resonance (San Diego, Calif. : 1997) 2016

Theoretical aspects of Magic Angle Spinning - Dynamic Nuclear Polarization.

• Hartmut Oschkinat

Journal of magnetic resonance (San Diego, Calif. : 1997) 2015

A modular toolkit to inhibit proline-rich motif-mediated protein-protein interactions.

• Hartmut Oschkinat

Proceedings of the National Academy of Sciences of the United States of America 2015

Alterations in creatine metabolism observed in experimental autoimmune myocarditis using ex vivo proton magic angle spinning MRS.

• Hartmut Oschkinat

NMR in biomedicine 2015

Light-Dark Adaptation of Channelrhodopsin Involves Photoconversion between the all-trans and 13-cis Retinal Isomers.

• Hartmut Oschkinat

Biochemistry 2015

Sensitivity and resolution of proton detected spectra of a deuterated protein at 40 and 60 kHz magic-angle-spinning.

• Nieuwkoop AJ; Franks WT; Rehbein K; Diehl A; Akbey Ü; Engelke F; Emsley L; Pintacuda G; Oschkinat H

Journal of biomolecular NMR 2015

AhR sensing of bacterial pigments regulates antibacterial defence.

• Hartmut Oschkinat

Nature 2014

Rapid proton-detected NMR assignment for proteins with fast magic angle spinning.

• Hartmut Oschkinat

Journal of the American Chemical Society 2014

Low-power polarization transfer between deuterons and spin-1/2 nuclei using adiabatic (RESPIRATION)CP in solid-state NMR.

• Hartmut Oschkinat

Physical chemistry chemical physics : PCCP 2014

Quadruple-resonance magic-angle spinning NMR spectroscopy of deuterated solid proteins.

• Hartmut Oschkinat

Angewandte Chemie (International ed. in English) 2014

Small-molecule inhibitors of AF6 PDZ-mediated protein-protein interactions.

• Hartmut Oschkinat

ChemMedChem 2014

These abstracts have been selected for presentation in 4 sessions throughout the meeting. Please refer to the PROGRAM for more details.

• Hartmut Oschkinat

European heart journal cardiovascular Imaging 2014

The mechanism of denaturation and the unfolded state of the α-helical membrane-associated protein Mistic.

• Hartmut Oschkinat

Journal of the American Chemical Society 2013

Dynamic nuclear polarization of spherical nanoparticles.

• Hartmut Oschkinat

Physical chemistry chemical physics : PCCP 2013

Preferential and specific binding of human αB-crystallin to a cataract-related variant of γS-crystallin.

• Kingsley CN; Brubaker WD; Markovic S; Diehl A; Brindley AJ; Oschkinat H; Martin RW

Structure (London, England : 1993) 2013

The clip-segment of the von Willebrand domain 1 of the BMP modulator protein Crossveinless 2 is preformed.

• Fiebig JE; Weidauer SE; Qiu LY; Bauer M; Schmieder P; Beerbaum M; Zhang JL; Oschkinat H; Sebald W; Mueller TD

Molecules (Basel, Switzerland) 2013

Lipophilic prodrugs of a triazole-containing colchicine analogue in liposomes: biological effects on human tumor cells.

• Kuznetsova NR; Svirshchevskaya EV; Sitnikov NS; Abodo L; Sutorius H; Zapke J; Velder J; Thomopoulou P; Oschkinat H; Prokop A; Schmalz HG; Fedorov AY; Vodovozova EL

Bioorganicheskaia khimiia 2013

A well-defined Pd hybrid material for the Z-selective semihydrogenation of alkynes characterized at the molecular level by DNP SENS.

• Conley MP; Drost RM; Baffert M; Gajan D; Elsevier C; Franks WT; Oschkinat H; Veyre L; Zagdoun A; Rossini A; Lelli M; Lesage A; Casano G; Ouari O; Thieuleux C

Chemistry (Weinheim an der Bergstrasse, Germany) 2013

Reduced activity of alkaline phosphatase due to host-guest interactions with humic superstructures.

• Mazzei P; Oschkinat H; Piccolo A

Chemosphere 2013

Out-and-back 13C-13C scalar transfers in protein resonance assignment by proton-detected solid-state NMR under ultra-fast MAS.

• Barbet-Massin E; Pell AJ; Jaudzems K; Franks WT; Retel JS; Kotelovica S; Akopjana I; Tars K; Emsley L; Oschkinat H; Lesage A; Pintacuda G

Journal of biomolecular NMR 2013

A Floquet description of phase alternated sequences for efficient homonuclear recoupling in solid perdeuterated systems.

• Jayanthi S; Akbey Ü; Uluca B; Oschkinat H; Vega S

Journal of magnetic resonance (San Diego, Calif. : 1997) 2013

Improved dynamic nuclear polarization surface-enhanced NMR spectroscopy through controlled incorporation of deuterated functional groups.

• Zagdoun A; Rossini AJ; Conley MP; Grüning WR; Schwarzwälder M; Lelli M; Franks WT; Oschkinat H; Copéret C; Emsley L; Lesage A

Angewandte Chemie (International ed. in English) 2013

Dynamic nuclear polarization enhanced NMR in the solid-state.

• Akbey U; Franks WT; Linden A; Orwick-Rydmark M; Lange S; Oschkinat H

Topics in current chemistry 2013

Developing DNP/Solid-State NMR Spectroscopy of Oriented Membranes

• Hartmut Oschkinat

Applied Magnetic Resonance 2012

High-Temperature Dynamic Nuclear Polarization Enhanced Magic-Angle-Spinning NMR

• Hartmut Oschkinat

Applied Magnetic Resonance 2012

In support of the BMRB.

• Markley JL; Akutsu H; Asakura T; Baldus M; Boelens R; Bonvin A; Kaptein R; Bax A; Bezsonova I; Gryk MR; Hoch JC; Korzhnev DM; Maciejewski MW; Case D; Yokoyama S

Nature structural & molecular biology 2012

Fast passage dynamic nuclear polarization on rotating solids.

• Mentink-Vigier F; Akbey U; Hovav Y; Vega S; Oschkinat H; Feintuch A

Journal of magnetic resonance (San Diego, Calif. : 1997) 2012

Efficient modeling of symmetric protein aggregates from NMR data.

• Bardiaux B; van Rossum BJ; Nilges M; Oschkinat H

Angewandte Chemie (International ed. in English) 2012

Broadband excitation pulses for high-field solid-state nuclear magnetic resonance spectroscopy.

• Loening NM; van Rossum BJ; Oschkinat H

Magnetic resonance in chemistry : MRC 2012

Practical aspects of high-sensitivity multidimensional ¹³C MAS NMR spectroscopy of perdeuterated proteins.

• Akbey U; Rossum BJ; Oschkinat H

Journal of magnetic resonance (San Diego, Calif. : 1997) 2012

Antigen 85C inhibition restricts Mycobacterium tuberculosis growth through disruption of cord factor biosynthesis.

• Warrier T; Tropis M; Werngren J; Diehl A; Gengenbacher M; Schlegel B; Schade M; Oschkinat H; Daffe M; Hoffner S; Eddine AN; Kaufmann SH

Antimicrobial agents and chemotherapy 2012

The effect of biradical concentration on the performance of DNP-MAS-NMR.

• Lange S; Linden AH; Akbey U; Franks WT; Loening NM; van Rossum BJ; Oschkinat H

Journal of magnetic resonance (San Diego, Calif. : 1997) 2012

Characterization of membrane proteins in isolated native cellular membranes by dynamic nuclear polarization solid-state NMR spectroscopy without purification and reconstitution.

• Jacso T; Franks WT; Rose H; Fink U; Broecker J; Keller S; Oschkinat H; Reif B

Angewandte Chemie (International ed. in English) 2012

Rapid solid-state NMR of deuterated proteins by interleaved cross-polarization from ¹H and ²H nuclei.

• Bjerring M; Paaske B; Oschkinat H; Akbey U; Nielsen NC

Journal of magnetic resonance (San Diego, Calif. : 1997) 2012

A comparison of NCO and NCA transfer methods for biological solid-state NMR spectroscopy.

• Loening NM; Bjerring M; Nielsen NC; Oschkinat H

Journal of magnetic resonance (San Diego, Calif. : 1997) 2012

Solid-state magic-angle spinning NMR of membrane proteins and protein-ligand interactions.

• Franks WT; Linden AH; Kunert B; van Rossum BJ; Oschkinat H

European journal of cell biology 2012

Enhanced Resolution and Coherence Lifetimes in the Solid-State NMR Spectroscopy of Perdeuterated Proteins under Ultrafast Magic-Angle Spinning

• Hartmut Oschkinat

The Journal of Physical Chemistry Letters 2011

Neurotoxin II bound to acetylcholine receptors in native membranes studied by dynamic nuclear polarization NMR.

• Linden AH; Lange S; Franks WT; Akbey U; Specker E; van Rossum BJ; Oschkinat H

Journal of the American Chemical Society 2011

Three-dimensional deuterium-carbon correlation experiments for high-resolution solid-state MAS NMR spectroscopy of large proteins.

• Lalli D; Schanda P; Chowdhury A; Retel J; Hiller M; Higman VA; Handel L; Agarwal V; Reif B; van Rossum B; Akbey U; Oschkinat H

Journal of biomolecular NMR 2011

A software framework for analysing solid-state MAS NMR data.

• Stevens TJ; Fogh RH; Boucher W; Higman VA; Eisenmenger F; Bardiaux B; van Rossum BJ; Oschkinat H; Laue ED

Journal of biomolecular NMR 2011

Cryogenic temperature effects and resolution upon slow cooling of protein preparations in solid state NMR.

• Linden AH; Franks WT; Akbey Ü; Lange S; van Rossum BJ; Oschkinat H

Journal of biomolecular NMR 2011

SNARE motif-mediated sorting of synaptobrevin by the endocytic adaptors clathrin assembly lymphoid myeloid leukemia (CALM) and AP180 at synapses.

• Koo SJ; Markovic S; Puchkov D; Mahrenholz CC; Beceren-Braun F; Maritzen T; Dernedde J; Volkmer R; Oschkinat H; Haucke V

Proceedings of the National Academy of Sciences of the United States of America 2011

Triple resonance cross-polarization for more sensitive 13C MAS NMR spectroscopy of deuterated proteins.

• Akbey U; Camponeschi F; van Rossum BJ; Oschkinat H

Chemphyschem : a European journal of chemical physics and physical chemistry 2011

Discovery, structure-activity relationship studies, and crystal structure of nonpeptide inhibitors bound to the Shank3 PDZ domain.

• Saupe J; Roske Y; Schillinger C; Kamdem N; Radetzki S; Diehl A; Oschkinat H; Krause G; Heinemann U; Rademann J

ChemMedChem 2011

Optimal (2)H rf Pulses and (2)H-(13)C Cross-Polarization Methods for Solid-State (2)H MAS NMR of Perdeuterated Proteins.

• Wei D; Akbey Ü; Paaske B; Oschkinat H; Reif B; Bjerring M; Nielsen NC

The journal of physical chemistry letters 2011

Proton-detected solid-state NMR spectroscopy of fibrillar and membrane proteins.

• Linser R; Dasari M; Hiller M; Higman V; Fink U; Lopez del Amo JM; Markovic S; Handel L; Kessler B; Schmieder P; Oesterhelt D; Oschkinat H; Reif B

Angewandte Chemie (International ed. in English) 2011

N-terminal domain of alphaB-crystallin provides a conformational switch for multimerization and structural heterogeneity.

• Jehle S; Vollmar BS; Bardiaux B; Dove KK; Rajagopal P; Gonen T; Oschkinat H; Klevit RE

Proceedings of the National Academy of Sciences of the United States of America 2011

The structure of MESD45-184 brings light into the mechanism of LDLR family folding.

• Köhler C; Lighthouse JK; Werther T; Andersen OM; Diehl A; Schmieder P; Du J; Holdener BC; Oschkinat H

Structure (London, England : 1993) 2011

Radio frequency assisted homonuclear recoupling - a Floquet description of homonuclear recoupling via surrounding heteronuclei in fully protonated to fully deuterated systems.

• Leskes M; Akbey U; Oschkinat H; van Rossum BJ; Vega S

Journal of magnetic resonance (San Diego, Calif. : 1997) 2011

Intermolecular protein-RNA interactions revealed by 2D 31P-15N magic angle spinning solid-state NMR spectroscopy.

• Jehle S; Falb M; Kirkpatrick JP; Oschkinat H; van Rossum BJ; Althoff G; Carlomagno T

Journal of the American Chemical Society 2010

Dynamic nuclear polarization of deuterated proteins.

• Akbey Ü; Franks WT; Linden A; Lange S; Griffin RG; van Rossum BJ; Oschkinat H

Angewandte Chemie (International ed. in English) 2010

Addressing protein-protein interactions with small molecules: a Pro-Pro dipeptide mimic with a PPII helix conformation as a module for the synthesis of PRD-binding ligands.

• Zaminer J; Brockmann C; Huy P; Opitz R; Reuter C; Beyermann M; Freund C; Müller M; Oschkinat H; Kühne R; Schmalz HG

Angewandte Chemie (International ed. in English) 2010

Solid-state NMR and SAXS studies provide a structural basis for the activation of alphaB-crystallin oligomers.

• Jehle S; Rajagopal P; Bardiaux B; Markovic S; Kühne R; Stout JR; Higman VA; Klevit RE; van Rossum BJ; Oschkinat H

Nature structural & molecular biology 2010

Azides derived from colchicine and their use in library synthesis: A practical entry to new bioactive derivatives of an old natural drug.

• Nicolaus N; Zapke J; Riesterer P; Neudörfl JM; Prokop A; Oschkinat H; Schmalz HG

ChemMedChem 2010

A MAS NMR study of the bacterial ABC transporter ArtMP.

• Lange V; Becker-Baldus J; Kunert B; van Rossum BJ; Casagrande F; Engel A; Roske Y; Scheffel FM; Schneider E; Oschkinat H

Chembiochem : a European journal of chemical biology 2010

A novel subtype of AP-1-binding motif within the palmitoylated trans-Golgi network/endosomal accessory protein Gadkin/gamma-BAR.

• Maritzen T; Schmidt MR; Kukhtina V; Higman VA; Strauss H; Volkmer R; Oschkinat H; Dotti CG; Haucke V

The Journal of biological chemistry 2010

Optimum levels of exchangeable protons in perdeuterated proteins for proton detection in MAS solid-state NMR spectroscopy.

• Akbey U; Lange S; Trent Franks W; Linser R; Rehbein K; Diehl A; van Rossum BJ; Reif B; Oschkinat H

Journal of biomolecular NMR 2010

Double-nucleus enhanced recoupling for efficient 13C MAS NMR correlation spectroscopy of perdeuterated proteins.

• Akbey U; Oschkinat H; van Rossum BJ

Journal of the American Chemical Society 2009

Large protein complexes with extreme rotational correlation times investigated in solution by magic-angle-spinning NMR spectroscopy.

• Mainz A; Jehle S; van Rossum BJ; Oschkinat H; Reif B

Journal of the American Chemical Society 2009

Regulation of endosomal membrane traffic by a Gadkin/AP-1/kinesin KIF5 complex.

• Schmidt MR; Maritzen T; Kukhtina V; Higman VA; Doglio L; Barak NN; Strauss H; Oschkinat H; Dotti CG; Haucke V

Proceedings of the National Academy of Sciences of the United States of America 2009

Assigning large proteins in the solid state: a MAS NMR resonance assignment strategy using selectively and extensively 13C-labelled proteins.

• Higman VA; Flinders J; Hiller M; Jehle S; Markovic S; Fiedler S; van Rossum BJ; Oschkinat H

Journal of biomolecular NMR 2009

Large-scale purification of ribosome-nascent chain complexes for biochemical and structural studies.

• Rutkowska A; Beerbaum M; Rajagopalan N; Fiaux J; Schmieder P; Kramer G; Oschkinat H; Bukau B

FEBS letters 2009

Loop 3 of short neurotoxin II is an additional interaction site with membrane-bound nicotinic acetylcholine receptor as detected by solid-state NMR spectroscopy.

• Krabben L; van Rossum BJ; Jehle S; Bocharov E; Lyukmanova EN; Schulga AA; Arseniev A; Hucho F; Oschkinat H

Journal of molecular biology 2009

NMR structure of the Wnt modulator protein Sclerostin.

• Weidauer SE; Schmieder P; Beerbaum M; Schmitz W; Oschkinat H; Mueller TD

Biochemical and biophysical research communications 2009

alphaB-crystallin: a hybrid solid-state/solution-state NMR investigation reveals structural aspects of the heterogeneous oligomer.

• Jehle S; van Rossum B; Stout JR; Noguchi SM; Falber K; Rehbein K; Oschkinat H; Klevit RE; Rajagopal P

Journal of molecular biology 2009

Crystalline Aluminum Hydroxy Fluorides: Structural Insights Obtained by High Field Solid State NMR and Trend Analyses

• Hartmut Oschkinat

The Journal of Physical Chemistry C 2008

Perspectives on NMR in drug discovery: a technique comes of age.

• Pellecchia M; Bertini I; Cowburn D; Dalvit C; Giralt E; Jahnke W; James TL; Homans SW; Kessler H; Luchinat C; Meyer B; Oschkinat H; Peng J; Schwalbe H; Siegal G

Nature reviews. Drug discovery 2008

A sequential assignment procedure for proteins that have intermediate line widths in MAS NMR spectra: amyloid fibrils of human CA150.WW2.

• Becker J; Ferguson N; Flinders J; van Rossum BJ; Fersht AR; Oschkinat H

Chembiochem : a European journal of chemical biology 2008

Delay of phagosome maturation by a mycobacterial lipid is reversed by nitric oxide.

• Axelrod S; Oschkinat H; Enders J; Schlegel B; Brinkmann V; Kaufmann SH; Haas A; Schaible UE

Cellular microbiology 2008

[2,3-(13)C]-labeling of aromatic residues--getting a head start in the magic-angle-spinning NMR assignment of membrane proteins.

• Hiller M; Higman VA; Jehle S; van Rossum BJ; Kühlbrandt W; Oschkinat H

Journal of the American Chemical Society 2008

Backbone and sidechain 1H, 13C and 15N resonance assignments of the Bright/ARID domain from the human JARID1C (SMCX) protein.

• Koehler C; Bishop S; Dowler EF; Schmieder P; Diehl A; Oschkinat H; Ball LJ

Biomolecular NMR assignments 2008

Resonance assignment of the RGS domain of human RGS10.

• Fedorov OY; Higman VA; Schmieder P; Leidert M; Diehl A; Elkins J; Soundararajan M; Oschkinat H; Ball LJ

Journal of biomolecular NMR 2007

Small-molecule scaffolds for CYP51 inhibitors identified by high-throughput screening and defined by X-ray crystallography.

• Podust LM; von Kries JP; Eddine AN; Kim Y; Yermalitskaya LV; Kuehne R; Ouellet H; Warrier T; Alteköster M; Lee JS; Rademann J; Oschkinat H; Waterman MR

Antimicrobial agents and chemotherapy 2007

Structural characterization of a new binding motif and a novel binding mode in group 2 WW domains.

• Ramirez-Espain X; Ruiz L; Martin-Malpartida P; Oschkinat H; Macias MJ

Journal of molecular biology 2007

Backbone and sidechain 1H, 13C and 15N resonance assignments of the RGS domain from human RGS14.

• Dowler EF; Diehl A; Schmieder P; Brockmann C; Elkins J; Soundararajan M; Oschkinat H; Ball LJ

Biomolecular NMR assignments 2007

J-deconvolution using maximum entropy reconstruction applied to 13C-13C solid-state cross-polarization magic-angle-spinning NMR of proteins.

• Scholz I; Jehle S; Schmieder P; Hiller M; Eisenmenger F; Oschkinat H; van Rossum BJ

Journal of the American Chemical Society 2007

Solid-state NMR of matrix metalloproteinase 12: an approach complementary to solution NMR.

• Balayssac S; Bertini I; Fälber K; Fragai M; Jehle S; Lelli M; Luchinat C; Oschkinat H; Yeo KJ

Chembiochem : a European journal of chemical biology 2007

The solution structure of the core of mesoderm development (MESD), a chaperone for members of the LDLR-family.

• Köhler C; Andersen OM; Diehl A; Krause G; Schmieder P; Oschkinat H

Journal of structural and functional genomics 2006

General structural motifs of amyloid protofilaments.

• Ferguson N; Becker J; Tidow H; Tremmel S; Sharpe TD; Krause G; Flinders J; Petrovich M; Berriman J; Oschkinat H; Fersht AR

Proceedings of the National Academy of Sciences of the United States of America 2006

Spectral editing: selection of methyl groups in multidimensional solid-state magic-angle spinning NMR.

• Jehle S; Hiller M; Rehbein K; Diehl A; Oschkinat H; van Rossum BJ

Journal of biomolecular NMR 2006

NMR assignment of human RGS18.

• Higman VA; Leidert M; Diehl A; Elkins J; Soundararajan M; Oschkinat H; Ball LJ

Journal of biomolecular NMR 2006

Discovery of low-molecular-weight ligands for the AF6 PDZ domain.

• Joshi M; Vargas C; Boisguerin P; Diehl A; Krause G; Schmieder P; Moelling K; Hagen V; Schade M; Oschkinat H

Angewandte Chemie (International ed. in English) 2006

High yield expression and purification of isotopically labelled human endothelin-1 for use in NMR studies.

• Mac TT; Beyermann M; Pires JR; Schmieder P; Oschkinat H

Protein expression and purification 2006

Solution structure and backbone dynamics of the Trypanosoma cruzi cysteine protease inhibitor chagasin.

• Salmon D; do Aido-Machado R; Diehl A; Leidert M; Schmetzer O; de A Lima AP; Scharfstein J; Oschkinat H; Pires JR

Journal of molecular biology 2006

1H, 15N and 13C assignments of the cysteine protease inhibitor chagasin from Trypanosoma cruzi.

• Aido-Machado Rd; Salmon D; Diehl A; Leidert M; Schmetzer O; de Lima AP; Scharfstein J; Oschkinat H; Pires JR

Journal of biomolecular NMR 2006

Structural basis for APPTPPPLPP peptide recognition by the FBP11WW1 domain.

• Pires JR; Parthier C; Aido-Machado Rd; Wiedemann U; Otte L; Böhm G; Rudolph R; Oschkinat H

Journal of molecular biology 2005

A modified strategy for sequence specific assignment of protein NMR spectra based on amino acid type selective experiments.

• Schubert M; Labudde D; Leitner D; Oschkinat H; Schmieder P

Journal of biomolecular NMR 2005

Influence of chemical shift tolerances on NMR structure calculations using ARIA protocols for assigning NOE data.

• Fossi M; Linge J; Labudde D; Leitner D; Nilges M; Oschkinat H

Journal of biomolecular NMR 2005

13C-labeled tyrosine residues as local IR probes for monitoring conformational changes in peptides and proteins.

• Tremmel S; Beyermann M; Oschkinat H; Bienert M; Naumann D; Fabian H

Angewandte Chemie (International ed. in English) 2005

Detection of dynamic water molecules in a microcrystalline sample of the SH3 domain of alpha-spectrin by MAS solid-state NMR.

• Chevelkov V; Faelber K; Diehl A; Heinemann U; Oschkinat H; Reif B

Journal of biomolecular NMR 2005

Studies of the intermediary metabolism in cultured cells of the insect Spodoptera frugiperda using 13C- or 15N-labelled tracers.

• Adam P; Gütlich M; Oschkinat H; Bacher A; Eisenreich W

BMC biochemistry 2005

SOLARIA: a protocol for automated cross-peak assignment and structure calculation for solid-state magic-angle spinning NMR spectroscopy.

• Fossi M; Castellani F; Nilges M; Oschkinat H; van Rossum BJ

Angewandte Chemie (International ed. in English) 2005

Solid-state magic-angle spinning NMR of outer-membrane protein G from Escherichia coli.

• Hiller M; Krabben L; Vinothkumar KR; Castellani F; van Rossum BJ; Kühlbrandt W; Oschkinat H

Chembiochem : a European journal of chemical biology 2005

The solution structure of an N-terminally truncated version of the yeast CDC24p PB1 domain shows a different beta-sheet topology.

• Leitner D; Wahl M; Labudde D; Krause G; Diehl A; Schmieder P; Pires JR; Fossi M; Wiedemann U; Leidert M; Oschkinat H

FEBS letters 2005

Quantitative study of the effects of chemical shift tolerances and rates of SA cooling on structure calculation from automatically assigned NOE data.

• Fossi M; Oschkinat H; Nilges M; Ball LJ

Journal of magnetic resonance (San Diego, Calif. : 1997) 2005

Recognition of proline-rich motifs by protein-protein-interaction domains.

• Ball LJ; Kühne R; Schneider-Mergener J; Oschkinat H

Angewandte Chemie (International ed. in English) 2005

NMR fragment screening: tackling protein-protein interaction targets.

• Schade M; Oschkinat H

Current opinion in drug discovery & development 2005

Letter to the Editor:1H,13C and15N Resonance Assignment of the Human Spred2 EVH1 Domain

• Hartmut Oschkinat

Journal of Biomolecular NMR 2004

Solution structure, backbone dynamics, and association behavior of the C-terminal BRCT domain from the breast cancer-associated protein BRCA1.

• Gaiser OJ; Ball LJ; Schmieder P; Leitner D; Strauss H; Wahl M; Kühne R; Oschkinat H; Heinemann U

Biochemistry 2004

Comparative structural and energetic analysis of WW domain-peptide interactions.

• Schleinkofer K; Wiedemann U; Otte L; Wang T; Krause G; Oschkinat H; Wade RC

Journal of molecular biology 2004

1H, 13C and 15N resonance assignments of the C-terminal BRCT domain from human BRCA1.

• Gaiser OJ; Oschkinat H; Heinemann U; Ball LJ

Journal of biomolecular NMR 2004

The SEP domain of p47 acts as a reversible competitive inhibitor of cathepsin L.

• Soukenik M; Diehl A; Leidert M; Sievert V; Büssow K; Leitner D; Labudde D; Ball LJ; Lechner A; Nägler DK; Oschkinat H

FEBS letters 2004

Quantification of PDZ domain specificity, prediction of ligand affinity and rational design of super-binding peptides.

• Wiedemann U; Boisguerin P; Leben R; Leitner D; Krause G; Moelling K; Volkmer-Engert R; Oschkinat H

Journal of molecular biology 2004

The oxidized subunit B8 from human complex I adopts a thioredoxin fold.

• Brockmann C; Diehl A; Rehbein K; Strauss H; Schmieder P; Korn B; Kühne R; Oschkinat H

Structure (London, England : 1993) 2004

Towards structure determination of neurotoxin II bound to nicotinic acetylcholine receptor: a solid-state NMR approach.

• Krabben L; van Rossum BJ; Castellani F; Bocharov E; Schulga AA; Arseniev AS; Weise C; Hucho F; Oschkinat H

FEBS letters 2004

The solution structure of the N-terminal domain of E3L shows a tyrosine conformation that may explain its reduced affinity to Z-DNA in vitro.

• Kahmann JD; Wecking DA; Putter V; Lowenhaupt K; Kim YG; Schmieder P; Oschkinat H; Rich A; Schade M

Proceedings of the National Academy of Sciences of the United States of America 2004

Sulindac-derived Ras pathway inhibitors target the Ras-Raf interaction and downstream effectors in the Ras pathway.

• Waldmann H; Karaguni IM; Carpintero M; Gourzoulidou E; Herrmann C; Brockmann C; Oschkinat H; Müller O

Angewandte Chemie (International ed. in English) 2004

The solution structure of the SODD BAG domain reveals additional electrostatic interactions in the HSP70 complexes of SODD subfamily BAG domains.

• Brockmann C; Leitner D; Labudde D; Diehl A; Sievert V; Büssow K; Kühne R; Oschkinat H

FEBS letters 2004

Determination of solid-state NMR structures of proteins by means of three-dimensional 15N-13C-13C dipolar correlation spectroscopy and chemical shift analysis.

• Castellani F; van Rossum BJ; Diehl A; Rehbein K; Oschkinat H

Biochemistry 2003

Design of N-substituted peptomer ligands for EVH1 domains.

• Zimmermann J; Kühne R; Volkmer-Engert R; Jarchau T; Walter U; Oschkinat H; Ball LJ

The Journal of biological chemistry 2003

1H detection in MAS solid-state NMR spectroscopy of biomacromolecules employing pulsed field gradients for residual solvent suppression.

• Chevelkov V; van Rossum BJ; Castellani F; Rehbein K; Diehl A; Hohwy M; Steuernagel S; Engelke F; Oschkinat H; Reif B

Journal of the American Chemical Society 2003

Measurement of multiple psi torsion angles in uniformly 13C,15N-labeled alpha-spectrin SH3 domain using 3D 15N-13C-13C-15N MAS dipolar-chemical shift correlation spectroscopy.

• Ladizhansky V; Jaroniec CP; Diehl A; Oschkinat H; Griffin RG

Journal of the American Chemical Society 2003

Assignment of amide proton signals by combined evaluation of HN, NN and HNCA MAS-NMR correlation spectra.

• van Rossum BJ; Castellani F; Pauli J; Rehbein K; Hollander J; de Groot HJ; Oschkinat H

Journal of biomolecular NMR 2003

Combining SPOT synthesis and native peptide ligation to create large arrays of WW protein domains.

• Toepert F; Knaute T; Guffler S; Pirés JR; Matzdorf T; Oschkinat H; Schneider-Mergener J

Angewandte Chemie (International ed. in English) 2003

The ScPex13p SH3 domain exposes two distinct binding sites for Pex5p and Pex14p.

• Pires JR; Hong X; Brockmann C; Volkmer-Engert R; Schneider-Mergener J; Oschkinat H; Erdmann R

Journal of molecular biology 2003

WW domain sequence activity relationships identified using ligand recognition propensities of 42 WW domains.

• Otte L; Wiedemann U; Schlegel B; Pires JR; Beyermann M; Schmieder P; Krause G; Volkmer-Engert R; Schneider-Mergener J; Oschkinat H

Protein science : a publication of the Protein Society 2003

Characterization of (1)H-(1)H distances in a uniformly (2)H,(15)N-labeled SH3 domain by MAS solid-state NMR spectroscopy (section sign).

• Reif B; Van Rossum BJ; Castellani F; Rehbein K; Diehl A; Oschkinat H

Journal of the American Chemical Society 2003

Prediction algorithm for amino acid types with their secondary structure in proteins (PLATON) using chemical shifts.

• Labudde D; Leitner D; Krüger M; Oschkinat H

Journal of biomolecular NMR 2003

Biosynthesis of riboflavin in archaea studies on the mechanism of 3,4-dihydroxy-2-butanone-4-phosphate synthase of Methanococcus jannaschii.

• Fischer M; Romisch W; Schiffmann S; Kelly M; Oschkinat H; Steinbacher S; Huber R; Eisenreich W; Richter G; Bacher A

The Journal of biological chemistry 2002

2D(13)C-(13)C MAS NMR correlation spectroscopy with mixing by true (1)H spin diffusion reveals long-range intermolecular distance restraints in ultra high magnetic field.

• de Boer I; Bosman L; Raap J; Oschkinat H; de Groot HJ

Journal of magnetic resonance (San Diego, Calif. : 1997) 2002

The structures of the active center in dark-adapted bacteriorhodopsin by solution-state NMR spectroscopy.

• Patzelt H; Simon B; terLaak A; Kessler B; Kühne R; Schmieder P; Oesterhelt D; Oschkinat H

Proceedings of the National Academy of Sciences of the United States of America 2002

Structure of a protein determined by solid-state magic-angle-spinning NMR spectroscopy.

• Castellani F; van Rossum B; Diehl A; Schubert M; Rehbein K; Oschkinat H

Nature 2002

A software tool for the prediction of Xaa-Pro peptide bond conformations in proteins based on 13C chemical shift statistics.

• Schubert M; Labudde D; Oschkinat H; Schmieder P

Journal of biomolecular NMR 2002

Relaxation, equilibrium oligomerization, and molecular symmetry of the VASP (336-380) EVH2 tetramer.

• Zimmermann J; Labudde D; Jarchau T; Walter U; Oschkinat H; Ball LJ

Biochemistry 2002

A 3-D structural model of solid self-assembled chlorophyll a/H(2)O from multispin labeling and MAS NMR 2-D dipolar correlation spectroscopy in high magnetic field.

• van Rossum BJ; Schulten EA; Raap J; Oschkinat H; de Groot HJ

Journal of magnetic resonance (San Diego, Calif. : 1997) 2002

EVH1 domains: structure, function and interactions.

• Ball LJ; Jarchau T; Oschkinat H; Walter U

FEBS letters 2002

MUSIC and aromatic residues: amino acid type-selective (1)H-(15)N correlations, III.

• Schubert M; Oschkinat H; Schmieder P

Journal of magnetic resonance (San Diego, Calif. : 1997) 2001

Assignment of the nonexchanging protons of the alpha-spectrin SH3 domain by two- and three-dimensional 1H-13C solid-state magic-angle spinning NMR and comparison of solution and solid-state proton chemical shifts.

• van Rossum BJ; Castellani F; Rehbein K; Pauli J; Oschkinat H

Chembiochem : a European journal of chemical biology 2001

Solution structures of the YAP65 WW domain and the variant L30 K in complex with the peptides GTPPPPYTVG, N-(n-octyl)-GPPPY and PLPPY and the application of peptide libraries reveal a minimal binding epitope.

• Pires JR; Taha-Nejad F; Toepert F; Ast T; Hoffmüller U; Schneider-Mergener J; Kühne R; Macias MJ; Oschkinat H

Journal of molecular biology 2001

The NMR structure of the 47-kDa dimeric enzyme 3,4-dihydroxy-2-butanone-4-phosphate synthase and ligand binding studies reveal the location of the active site.

• Kelly MJ; Ball LJ; Krieger C; Yu Y; Fischer M; Schiffmann S; Schmieder P; Kühne R; Bermel W; Bacher A; Richter G; Oschkinat H

Proceedings of the National Academy of Sciences of the United States of America 2001

Using flexible loop mimetics to extend phi-value analysis to secondary structure interactions.

• Ferguson N; Pires JR; Toepert F; Johnson CM; Pan YP; Volkmer-Engert R; Schneider-Mergener J; Daggett V; Oschkinat H; Fersht A

Proceedings of the National Academy of Sciences of the United States of America 2001

Ultrafast folding of WW domains without structured aromatic clusters in the denatured state.

• Ferguson N; Johnson CM; Macias M; Oschkinat H; Fersht A

Proceedings of the National Academy of Sciences of the United States of America 2001

Amino acid type-selective backbone 1H-15N-correlations for Arg and Lys.

• Schubert M; Oschkinat H; Schmieder P

Journal of biomolecular NMR 2001

Secondary chemical shifts in immobilized peptides and proteins: a qualitative basis for structure refinement under magic angle spinning.

• Luca S; Filippov DV; van Boom JH; Oschkinat H; de Groot HJ; Baldus M

Journal of biomolecular NMR 2001

High-throughput three-dimensional protein structure determination.

• Heinemann U; Illing G; Oschkinat H

Current opinion in biotechnology 2001

Backbone and side-chain 13C and 15N signal assignments of the alpha-spectrin SH3 domain by magic angle spinning solid-state NMR at 17.6 Tesla.

• Pauli J; Baldus M; van Rossum B; de Groot H; Oschkinat H

Chembiochem : a European journal of chemical biology 2001

Synthesis of an Array Comprising 837 Variants of the hYAP WW Protein Domain This work was supported by the DFG (INK 16/B1-1), by the Fonds der Chemischen Industrie, and by the Universitätsklinikum Charité Berlin.

• Toepert F; Pires JR; Landgraf C; Oschkinat H; Schneider-Mergener J

Angewandte Chemie (International ed. in English) 2001

MUSIC, selective pulses, and tuned delays: amino acid type-selective (1)H-(15)N correlations, II.

• Schubert M; Oschkinat H; Schmieder P

Journal of magnetic resonance (San Diego, Calif. : 1997) 2001

Improving the refolding yield of interleukin-4 through the optimization of local interactions.

• Domingues H; Peters J; Schneider KH; Apeler H; Sebald W; Oschkinat H; Serrano L

Journal of biotechnology 2000

Dual epitope recognition by the VASP EVH1 domain modulates polyproline ligand specificity and binding affinity.

• Ball LJ; Kühne R; Hoffmann B; Häfner A; Schmieder P; Volkmer-Engert R; Hof M; Wahl M; Schneider-Mergener J; Walter U; Oschkinat H; Jarchau T

The EMBO journal 2000

Bridging the gap: A set of selective 1H-15N-correlations to link sequential neighbors of prolines.

• Schubert M; Ball LJ; Oschkinat H; Schmieder P

Journal of biomolecular NMR 2000

Structural analysis of WW domains and design of a WW prototype.

• Macias MJ; Gervais V; Civera C; Oschkinat H

Nature structural biology 2000

Sample optimization and identification of signal patterns of amino acid side chains in 2D RFDR spectra of the alpha-spectrin SH3 domain.

• Pauli J; van Rossum B; Förster H; de Groot HJ; Oschkinat H

Journal of magnetic resonance (San Diego, Calif. : 1997) 2000

An integrated approach to structural genomics.

• Heinemann U; Frevert J; Hofmann K; Illing G; Maurer C; Oschkinat H; Saenger W

Progress in biophysics and molecular biology 2000

Interaction of a PDZ Protein Domain with a Synthetic Library of All Human Protein C Termini

• Hartmut Oschkinat

Angewandte Chemie International Edition 1999

The entire metabolite spectrum of the green alga Scenedesmus obliquus in isotope-labelled form

• Hartmut Oschkinat

Phytochemistry 1999

A new type of PDZ domain recognition.

• Oschkinat H

Nature structural biology 1999

MUSIC in triple-resonance experiments: amino acid type-selective (1)H-(15)N correlations

• Schubert M; Smalla M; Schmieder P; Oschkinat H

Journal of magnetic resonance (San Diego, Calif. : 1997) 1999

Solution structure of the receptor tyrosine kinase EphB2 SAM domain and identification of two distinct homotypic interaction sites.

• Smalla M; Schmieder P; Kelly M; Ter Laak A; Krause G; Ball L; Wahl M; Bork P; Oschkinat H

Protein science : a publication of the Protein Society 1999

The solution structure of the Zalpha domain of the human RNA editing enzyme ADAR1 reveals a prepositioned binding surface for Z-DNA.

• Schade M; Turner CJ; Kühne R; Schmieder P; Lowenhaupt K; Herbert A; Rich A; Oschkinat H

Proceedings of the National Academy of Sciences of the United States of America 1999

A 6 bp Z-DNA hairpin binds two Z alpha domains from the human RNA editing enzyme ADAR1.

• Schade M; Behlke J; Lowenhaupt K; Herbert A; Rich A; Oschkinat H

FEBS letters 1999

Rational design of a GCN4-derived mimetic of interleukin-4.

• Domingues H; Cregut D; Sebald W; Oschkinat H; Serrano L

Nature structural biology 1999

Application of amino acid type-specific 1H- and 14N-labeling in a 2H-, 15N-labeled background to a 47 kDa homodimer: potential for NMR structure determination of large proteins.

• Kelly MJ; Krieger C; Ball LJ; Yu Y; Richter G; Schmieder P; Bacher A; Oschkinat H

Journal of biomolecular NMR 1999

NMR studies on the 46-kDa dimeric protein, 3,4-dihydroxy-2-butanone 4-phosphate synthase, using 2H, 13C, and 15N-labelling.

• Richter G; Kelly M; Krieger C; Yu Y; Bermel W; Karlsson G; Bacher A; Oschkinat H

European journal of biochemistry 1999

Signal selection in high-resolution NMR by pulsed field gradients.

• Thomas DJ; Mitschang L; Simon B; Oschkinat H

Journal of magnetic resonance (San Diego, Calif. : 1997) 1999

Multidimensional CP-MAS 13C NMR of uniformly enriched chlorophyll

• Hartmut Oschkinat

Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy 1998

Multiplicity-Selective Coherence Transfer Steps for the Design of Amino Acid-Selective Experiments—A Triple-Resonance Experiment Selective for Asn and Gln

• Hartmut Oschkinat

Journal of Magnetic Resonance 1998

Heteronuclear relaxation study of the PH domain of beta-spectrin: restriction of loop motions upon binding inositol trisphosphate.

• Gryk MR; Abseher R; Simon B; Nilges M; Oschkinat H

Journal of molecular biology 1998

Specific interactions between the syntrophin PDZ domain and voltage-gated sodium channels.

• Schultz J; Hoffmüller U; Krause G; Ashurst J; Macias MJ; Schmieder P; Schneider-Mergener J; Oschkinat H

Nature structural biology 1998

Towards structural investigations on isotope labelled native bacteriorhodopsin in detergent micelles by solution-state NMR spectroscopy

• Hartmut Oschkinat

Journal of Biomolecular NMR 1997

NMR Investigations of the Role of the Sugar Moiety in Glycosylated Recombinant Human Granulocyte-Colony-Stimulating Factor

• Hartmut Oschkinat

European Journal of Biochemistry 1997

Constant-Time HQQC Experiment for Protein NMR Spectroscopy

• Hartmut Oschkinat

Journal of Magnetic Resonance 1997

Tools for the automated assignment of high-resolution three-dimensional protein NMR spectra based on pattern recognition techniques.

• Croft D; Kemmink J; Neidig KP; Oschkinat H

Journal of biomolecular NMR 1997

A small region in phosducin inhibits G-protein betagamma-subunit function.

• Blüml K; Schnepp W; Schröder S; Beyermann M; Macias M; Oschkinat H; Lohse MJ

The EMBO journal 1997

Characterization of pheophytin ground states in Rhodobacter sphaeroides R26 photosynthetic reaction centers from multispin pheophytin enrichment and 2-D 13C MAS NMR dipolar correlation spectroscopy.

• Egorova-Zachernyuk TA; van Rossum B; Boender GJ; Franken E; Ashurst J; Raap J; Gast P; Hoff AJ; Oschkinat H; de Groot HJ

Biochemistry 1997

Automated NOESY interpretation with ambiguous distance restraints: the refined NMR solution structure of the pleckstrin homology domain from beta-spectrin.

• Nilges M; Macias MJ; O'Donoghue SI; Oschkinat H

Journal of molecular biology 1997

Rab7: NMR and kinetics analysis of intact and C-terminal truncated constructs.

• Neu M; Brachvogel V; Oschkinat H; Zerial M; Metcalf P

Proteins 1997

An approach to global fold determination using limited NMR data from larger proteins selectively protonated at specific residue types

• Hartmut Oschkinat

Journal of Biomolecular NMR 1996

An Approach to the Structure Determination of Larger Proteins Using Triple Resonance NMR Experiments in Conjunction with Random Fractional Deuteration

• Hartmut Oschkinat

Journal of the American Chemical Society 1996

Structure of the WW domain of a kinase-associated protein complexed with a proline-rich peptide.

• Macias MJ; Hyvönen M; Baraldi E; Schultz J; Sudol M; Saraste M; Oschkinat H

Nature 1996

NMR analysis of site-specific ligand binding in oligomeric proteins. Dynamic studies on the interaction of riboflavin synthase with trifluoromethyl-substituted intermediates.

• Scheuring J; Fischer M; Cushman M; Lee J; Bacher A; Oschkinat H

Biochemistry 1996

Geometrical representation of coherence transfer selection by pulsed field gradients in high‐resolution nuclear magnetic resonance

• Hartmut Oschkinat

The Journal of Chemical Physics 1995

MAS NMR structure refinement of uniformly 13C enriched chlorophyll a/water aggregates with 2D dipolar correlation spectroscopy

• Hartmut Oschkinat

Chemical Physics Letters 1995

Assignment and secondary-structure determination of monomeric bovine seminal ribonuclease employing computer-assisted evaluation of homonuclear three-dimensional 1H-NMR spectra.

• D'Ursi A; Oschkinat H; Cieslar C; Picone D; D'Alessio G; Amodeo P; Temussi PA

European journal of biochemistry 1995

Structure of the binding site for inositol phosphates in a PH domain.

• Hyvönen M; Macias MJ; Nilges M; Oschkinat H; Saraste M; Wilmanns M

The EMBO journal 1995

Receptor binding properties of four-helix-bundle growth factors deduced from electrostatic analysis.

• Demchuk E; Mueller T; Oschkinat H; Sebald W; Wade RC

Protein science : a publication of the Protein Society 1994

Protein Structure Determination with Three- and Four-Dimensional NMR Spectroscopy

• Hartmut Oschkinat

Angewandte Chemie International Edition in English 1994

Structure of the pleckstrin homology domain from beta-spectrin.

• Macias MJ; Musacchio A; Ponstingl H; Nilges M; Saraste M; Oschkinat H

Nature 1994

Antagonist design through forced electrostatic mismatch.

• Müller T; Sebald W; Oschkinat H

Nature structural biology 1994

Aspects of receptor binding and signalling of interleukin-4 investigated by site-directed mutagenesis and NMR spectroscopy.

• Müller T; Dieckmann T; Sebald W; Oschkinat H

Journal of molecular biology 1994

Automated assignment of multidimensional nuclear magnetic resonance spectra.

• Oschkinat H; Croft D

Methods in enzymology 1994

Secondary NOE pathways in 2D NOESY spectra of proteins estimated from homonuclear three-dimensional NOE-NOE nuclear magnetic resonance spectroscopy

• Hartmut Oschkinat

Journal of Magnetic Resonance (1969) 1992

Removal of zero-quantum interference in NOESY spectra of proteins by utilizing the natural inhomogeneity of the radiofrequency field

• Hartmut Oschkinat

Journal of Biomolecular NMR 1992

Conformation of 6,7-dimethyl-8-ribityllumazine bound to β-subunits of heavy riboflavin synthase: Transferred nuclear overhauser effect (TrNOE) studies employing ω1-13C-filtered NOESY including a novel technique for zero quantum suppression

• Hartmut Oschkinat

Journal of Biomolecular NMR 1992

Two-dimensional nuclear magnetic resonance studies of an intercalation complex between the novel semisynthetic anthracycline 3'-deamino-3'-(2-methoxy-4-morpholinyl)-doxorubicin and the hexanucleotide duplex d(CGTACG).

• Odefey C; Westendorf J; Dieckmann T; Oschkinat H

Chemico-biological interactions 1992

The interaction of thrombin with fibrinogen. A structural basis for its specificity.

• Stubbs MT; Oschkinat H; Mayr I; Huber R; Angliker H; Stone SR; Bode W

European journal of biochemistry 1992

Evidence for tyrosine-linked glycosaminoglycan in a bacterial surface protein.

• Peters J; Rudolf S; Oschkinat H; Mengele R; Sumper M; Kellermann J; Lottspeich F; Baumeister W

Biological chemistry Hoppe-Seyler 1992

Structures of proteins in solution derived from homonuclear three-dimensional NOE-NOE nuclear magnetic resonance spectroscopy. High-resolution structure of squash trypsin inhibitor

• Hartmut Oschkinat

Journal of the American Chemical Society 1991

Homonuclear three-dimensional NOE-NOE Nuclear magnetic resonance spectroscopy of proteins in water

• Hartmut Oschkinat

Journal of Magnetic Resonance (1969) 1991

Application of the Karhunen-Loéve transformation to the suppression of undesired resonances in three-dimensional NMR

• Hartmut Oschkinat

Journal of Magnetic Resonance (1969) 1991

Purification and characterization of a chicken egg white cystatin variant expressed in an Escherichia coli pIN-III-ompA system.

• Auerswald EA; Genenger G; Mentele R; Lenzen S; Assfalg-Machleidt I; Mitschang L; Oschkinat H; Fritz H

European journal of biochemistry 1991

Assignment of protein NMR spectra in the light of homonuclear 3D spectroscopy: an automatable procedure based on 3D TOCSY-TOCSY and 3D TOCSY-NOESY.

• Oschkinat H; Holak TA; Cieslar C

Biopolymers 1991

3D TOCSY-TOCSY processing using linear prediction, as a potential technique for automated assignment

• Hartmut Oschkinat

Journal of Magnetic Resonance (1969) 1990

A program for the evaluation of 3D spectra applied to the sequential assignment of BPTI utilizing 3D TOCSY-NOESY

• Hartmut Oschkinat

Journal of Magnetic Resonance (1969) 1990

Fast Heteronuclear 3D NMR Spectroscopy

• Hartmut Oschkinat

Angewandte Chemie International Edition in English 1990

3D Heteronuclear NMR techniques for carbon-13 in natural abundance

• Hartmut Oschkinat

Journal of the American Chemical Society 1990

Recognition of secondary-structure elements in 3D TOCSY-NOESY spectra of proteins. Interpretation of 3D cross-peak amplitudes

• Hartmut Oschkinat

Journal of Magnetic Resonance (1969) 1990

Solution conformation of thymosin beta 4: a nuclear magnetic resonance and simulated annealing study.

• Zarbock J; Oschkinat H; Hannappel E; Kalbacher H; Voelter W; Holak TA

Biochemistry 1990

1H NMR assignments of sidechain conformations in proteins using a high-dimensional potential in the simulated annealing calculations.

• Habazettl J; Cieslar C; Oschkinat H; Holak TA

FEBS letters 1990

Detection of metabolites in body fluids and biological tissue by a 1D soft COSY technique.

• Stryjewski D; Oschkinat H; Leibfritz D

Magnetic resonance in medicine 1990

Three-dimensional homonuclear Hartmann-Hahn-nuclear overhauser enhancement spectroscopy in H2O and its application to proteins

• Hartmut Oschkinat

Journal of Magnetic Resonance (1969) 1989

Longitudinal relaxation pathways in scalar-coupled systems

• Hartmut Oschkinat

Journal of Magnetic Resonance (1969) 1989

Practical and theoretical aspects of three-dimensional homonuclear Hartmann-Hahn-nuclear overhauser enhancement spectroscopy of proteins

• Hartmut Oschkinat

Journal of Magnetic Resonance (1969) 1989

Application of the soft NOESY technique to the measurement of individual transition probabilities

• Hartmut Oschkinat

Journal of Magnetic Resonance (1969) 1989

Improved strategies for the determination of protein structures from NMR data: the solution structure of acyl carrier protein.

• Holak TA; Nilges M; Oschkinat H

FEBS letters 1989

Determination of relaxation pathways in coupled spin systems by two-dimensional NMR exchange spectroscopy with small flip angles

• Hartmut Oschkinat

Journal of the American Chemical Society 1987

Multiplet effects in double-quantum spectra

• Hartmut Oschkinat

Journal of Magnetic Resonance (1969) 1987

Application of the z-COSY technique with a modified pulse sequence to measurement of coupling constants in macromolecules

• Hartmut Oschkinat

Journal of Magnetic Resonance (1969) 1987

z-Filtered double-quantum NMR spectra and automated analysis by pattern recognition

• Hartmut Oschkinat

Journal of Magnetic Resonance (1969) 1987

Simplification of Spectra for the Determination of Coupling Constants from Homonuclear Correlated 2D NMR Spectra

• Hartmut Oschkinat

Angewandte Chemie International Edition in English 1985

Peptide conformations. Part 31. The conformation of cyclosporin a in the crystal and in solution

• Hartmut Oschkinat

Helvetica Chimica Acta 1985

Differences andsums of traces within,COSY spectra (DISCO) for the extraction of coupling constants: ‘Decoupling’ after the measurement

• Hartmut Oschkinat

Magnetic Resonance in Chemistry 1985

Peptide conformations. Part 30. Assignment of the1H-,13C-, and15N-NMR spectra of cyclosporin A in CDCl3 and C6D6 by a combination of homo- and heteronuclear two-dimensional techniques

• Hartmut Oschkinat

Helvetica Chimica Acta 1985

The Structure of the Lichen Macrolide(+)-Aspicilin

• Hartmut Oschkinat

Angewandte Chemie International Edition in English 1985