Adam Lange

Death, taxes, and rhomboids: Understanding the ubiquitous roles of the rhomboid protein superfamily

• Henry Sawczyc; Spyridon Kosteletos; Adam Lange

Journal of Biological Chemistry 2025

DFT calculations do not explain enantiospecific NMR responses in cross polarization

• Anton F. Ketzel; Caspar J. Schattenberg; Veniamin Chevelkov; Adam Lange; Han Sun

Nature Communications 2025

Atomistic Mechanism of Calcium-Mediated Inward Rectification of the MthK Potassium Channel by Solid-State NMR and MD Simulations

• Carl Öster; Reinier de Vries; Juan Li; Denis Qoraj; Sascha Lange; Chaowei Shi; Wojciech Kopec; Bert L de Groot; Adam Lange

Journal of the American Chemical Society 2025

Structural Transition from Closed to Open for the Influenza A M2 Proton Channel as Observed by Proton-Detected Solid-State NMR

• Swantje Mohr; Caspar Schattenberg; Tillmann Utesch; Henry Sawczyc; Veniamin Chevelkov; Sascha Lange; Jacek Kozuch; Han Sun; Adam Lange

Journal of the American Chemical Society 2025

Carbazole‐Based Thin Microporous Polymer Films for Photocatalytic Hydrogen Evolution

• Veit Dippold; Hüseyin Küçükkeçeci; Eugenia Bosler; Johannes Schmidt; Samrat Ghosh; Gregor Michl; Islam E. Khalil; Lisa Gerland; Adam Lange; Dirk Oberschmidt; Arne Thomas

Advanced Materials 2025

Evaluation of TOCSY mixing for sensitivity-enhancement in solid-state NMR and application of 4D experiments for side-chain assignments of the full-length 30 kDa membrane protein GlpG

• Carl Öster; Veniamin Chevelkov; Adam Lange

Journal of Biomolecular NMR 2025

In Situ Spectroscopic Detection of Large‐Scale Reorientations of Transmembrane Helices During Influenza A M2 Channel Opening**

• Ronja Rabea Paschke; Swantje Mohr; Sascha Lange; Adam Lange; Jacek Kozuch

Angewandte Chemie International Edition 2023

In situ‐spektroskopische Detektion der weitreichenden Reorientierung von Transmembranhelices während der Öffnung des Influenza A M2‐Kanals**

• Ronja Rabea Paschke; Swantje Mohr; Sascha Lange; Adam Lange; Jacek Kozuch

Angewandte Chemie 2023

In-situ spectroscopic detection of large-scale reorientations of transmembrane α-helices during viroporin channel opening

• Ronja Paschke; Swantje Mohr; Sascha Lange; Adam Lange; Jacek Kozuch

Accurate Determination of Motional Amplitudes in Biomolecules by Solid-State NMR

• Veniamin Chevelkov; Sascha Lange; Henry Sawczyc; Adam Lange

ACS Physical Chemistry Au 2023

The opening dynamics of the lateral gate regulates the activity of rhomboid proteases

• Claudia Bohg; Carl Öster; Berke Türkaydin; Michael Lisurek; Pascal Sanchez-Carranza; Sascha Lange; Tillmann Utesch; Han Sun; Adam Lange

Science Advances 2023

Architecture of the flexible tail tube of bacteriophage SPP1

• Maximilian Zinke; Katrin A. A. Sachowsky; Carl Öster; Sophie Zinn-Justin; Raimond Ravelli; Gunnar F. Schröder; Michael Habeck; Adam Lange

Nature Communications 2020

Dynamic interactions of CbiN and CbiM trigger activity of a cobalt energy-coupling-factor transporter

• Adam Lange

Biochimica et Biophysica Acta (BBA) - Biomembranes 2020

Spinal Column Architecture of the Flexible SPP1 Bacteriophage Tail Tube

• Maximilian Zinke; Katrin A. A. Sachowsky; Carl Öster; Sophie Zinn-Justin; Raimond B.G. Ravelli; Gunnar F. Schröder; Michael Habeck; Adam Lange

Protein resonance assignment by BSH‐CP‐based 3D solid‐state NMR experiments: A practical guide

• Jutta Hoffmann; Julia Ruta; Chaowei Shi; Kitty Hendriks; Veniamin Chevelkov; W. Trent Franks; Hartmut Oschkinat; Karin Giller; Stefan Becker; Adam Lange

Magnetic Resonance in Chemistry 2020

Comparison of the 3D structures of mouse and human α-synuclein fibrils by solid-state NMR and STEM

• Adam Lange

Journal of Structural Biology 2019

Characterization of H/D exchange in type 1 pili by proton-detected solid-state NMR and molecular dynamics simulations

• Adam Lange

Journal of Biomolecular NMR 2019

The conduction pathway of potassium channels is water free under physiological conditions

• Carl Öster; Kitty Hendriks; Wojciech Kopec; Veniamin Chevelkov; Chaowei Shi; Dagmar Michl; Sascha Lange; Han Sun; Bert L. de Groot; Adam Lange

Science Advances 2019

Structure and Dynamics of the Rhomboid Protease GlpG in Liposomes Studied by Solid-State NMR

• Chaowei Shi; Carl Öster; Claudia Bohg; Longmei Li; Sascha Lange; Veniamin Chevelkov; Adam Lange

Journal of the American Chemical Society 2019

Measurement of backbone hydrogen-deuterium exchange in the type III secretion system needle protein PrgI by solid-state NMR

• Adam Lange

Journal of Magnetic Resonance 2017

Emerin self‐assembly mechanism: role of the LEM domain

• Adam Lange

The FEBS Journal 2017

Backbone assignment of perdeuterated proteins by solid-state NMR using proton detection and ultrafast magic-angle spinning

• Adam Lange

Nature Protocols 2017

Sensory domain contraction in histidine kinase CitA triggers transmembrane signaling in the membrane-bound sensor

• Adam Lange

Proceedings of the National Academy of Sciences 2017

A Two-Component Adhesive: Tau Fibrils Arise from a Combination of a Well-Defined Motif and Conformationally Flexible Interactions

• Adam Lange

Journal of the American Chemical Society 2017

Bacteriophage Tail‐Tube Assembly Studied by Proton‐Detected 4D Solid‐State NMR

• Maximilian Zinke; Pascal Fricke; Camille Samson; Songhwan Hwang; Joseph S. Wall; Sascha Lange; Sophie Zinn‐Justin; Adam Lange

Angewandte Chemie International Edition 2017

Bacteriophage Tail‐Tube Assembly Studied by Proton‐Detected 4D Solid‐State NMR

• Maximilian Zinke; Pascal Fricke; Camille Samson; Songhwan Hwang; Joseph S. Wall; Sascha Lange; Sophie Zinn‐Justin; Adam Lange

Angewandte Chemie 2017

Perspectives for sensitivity enhancement in proton-detected solid-state NMR of highly deuterated proteins by preserving water magnetization

• Adam Lange

Journal of Biomolecular NMR 2015

Solid-state NMR, electrophysiology and molecular dynamics characterization of human VDAC2

• Adam Lange

Journal of Biomolecular NMR 2015

Hybrid Structure of the Type 1 Pilus of UropathogenicEscherichia coli

• Adam Lange

Angewandte Chemie International Edition 2015

Atomic-resolution structure of cytoskeletal bactofilin by solid-state NMR

• Adam Lange

Science Advances 2015

Structural heterogeneity in microcrystalline ubiquitin studied by solid-state NMR

• Adam Lange

Protein Science 2015

Specific 13C labeling of leucine, valine and isoleucine methyl groups for unambiguous detection of long-range restraints in protein solid-state NMR studies

• Adam Lange

Journal of Magnetic Resonance 2015

Recovery of Bulk Proton Magnetization and Sensitivity Enhancement in Ultrafast Magic-Angle Spinning Solid-State NMR

• Adam Lange

The Journal of Physical Chemistry B 2015

β-Helical architecture of cytoskeletal bactofilin filaments revealed by solid-state NMR

• Adam Lange

Proceedings of the National Academy of Sciences 2015

BSH-CP based 3D solid-state NMR experiments for protein resonance assignment

• Adam Lange

Journal of Biomolecular NMR 2014

Towards automatic protein backbone assignment using proton-detected 4D solid-state NMR data

• Adam Lange

Journal of Biomolecular NMR 2014

Proton-detected MAS NMR experiments based on dipolar transfers for backbone assignment of highly deuterated proteins

• Adam Lange

Journal of Magnetic Resonance 2014

NMR-Based Detection of Hydrogen/Deuterium Exchange in Liposome-Embedded Membrane Proteins

• Adam Lange

PLoS ONE 2014

High-resolution structure of the Shigella type-III secretion needle by solid-state NMR and cryo-electron microscopy

• Adam Lange

Nature Communications 2014

Revisiting the Synthesis and Elucidating the Structure of Potassium Cyclopentadienyldicarbonylruthenate, K[CpRu(CO)2]

• Adam Lange

Organometallics 2014

Synthetic Access to a Hydrocarbon-Soluble Trifluorinated Ge(II) Compound and its Sn(II) Congener

• Adam Lange

Journal of the American Chemical Society 2014

Nucleotide Interactions of the Human Voltage-dependent Anion Channel

• Adam Lange

Journal of Biological Chemistry 2014

Studies on the MxiH Protein in T3SS Needles Using DNP-Enhanced ssNMR Spectroscopy

• Adam Lange

ChemPhysChem 2014

Spontaneous Aggregation of the Insulin-Derived Steric Zipper Peptide VEALYL Results in Different Aggregation Forms with Common Features

• Adam Lange

Journal of Molecular Biology 2014

Efficient band-selective homonuclear CO–CA cross-polarization in protonated proteins

• Adam Lange

Journal of Biomolecular NMR 2013

Cryogenic solid state NMR studies of fibrils of the Alzheimer’s disease amyloid-β peptide: perspectives for DNP

• Adam Lange

Journal of Biomolecular NMR 2013

Atomic Structure and Handedness of the Building Block of a Biological Assembly

• Adam Lange

Journal of the American Chemical Society 2013

Efficient CO–CA transfer in highly deuterated proteins by band-selective homonuclear cross-polarization

• Adam Lange

Journal of Magnetic Resonance 2013

The Common Structural Architecture of Shigella flexneri and Salmonella typhimurium Type Three Secretion Needles

• Adam Lange

PLoS Pathogens 2013

A straightforward method for stereospecific assignment of val and leu prochiral methyl groups by solid-state NMR: Scrambling in the [2-13C]Glucose labeling scheme

• Adam Lange

Journal of Magnetic Resonance 2013

Structural characterization of supramolecular assemblies by 13C spin dilution and 3D solid-state NMR

• Adam Lange

Journal of Biomolecular NMR 2013

β-Barrel Mobility Underlies Closure of the Voltage-Dependent Anion Channel

• Adam Lange

Structure 2012

β-Sheet Core of Tau Paired Helical Filaments Revealed by Solid-State NMR

• Adam Lange

Journal of the American Chemical Society 2012

Lewis base mediated dismutation of trichlorosilane

• Adam Lange

Chemical Communications 2012

Monomeric Sn(ii) and Ge(ii) hydrides supported by a tridentate pincer-based ligand

• Adam Lange

Chemical Communications 2012

Structural Comparison of Mouse and Human α-Synuclein Amyloid Fibrils by Solid-State NMR

• Adam Lange

Journal of Molecular Biology 2012

Atomic model of the type III secretion system needle

• Adam Lange

Nature 2012

Mixed Crystalline Lithium Organics and Interconversion in Solution

• Adam Lange

Organometallics 2012

Lewis Base Mediated Autoionization of GeCl2 and SnCl2

• Adam Lange

Journal of the American Chemical Society 2012

Probing Water Accessibility in HET-s(218–289) Amyloid Fibrils by Solid-State NMR

• Adam Lange

Journal of Molecular Biology 2011

Zwitterionic Si-C-Si-P and Si-P-Si-P Four-Membered Rings with Two-Coordinate Phosphorus Atoms

• Adam Lange

Angewandte Chemie International Edition 2011

Pure α-Metallated Benzyllithium from a Single-Crystal-to-Single-Crystal Transition

• Adam Lange

Angewandte Chemie International Edition 2011

13C Spin Dilution for Simplified and Complete Solid-State NMR Resonance Assignment of Insoluble Biological Assemblies

• Adam Lange

Journal of the American Chemical Society 2011

Preparation of RSn(I)–Sn(I)R with Two Unsymmetrically Coordinated Sn(I) Atoms and Subsequent Gentle Activation of P4

• Adam Lange

Journal of the American Chemical Society 2011

Probing Molecular Motion by Double-Quantum (13C,13C) Solid-State NMR Spectroscopy: Application to Ubiquitin

• Adam Lange

Journal of the American Chemical Society 2010

Functional dynamics in the voltage-dependent anion channel

• Adam Lange

Proceedings of the National Academy of Sciences 2010

Supramolecular Interactions Probed by13C−13C Solid-State NMR Spectroscopy

• Adam Lange

Journal of the American Chemical Society 2010

Atomic-Resolution Three-Dimensional Structure of HET-s(218−289) Amyloid Fibrils by Solid-State NMR Spectroscopy

• Adam Lange

Journal of the American Chemical Society 2010

Tailored low-power cross-polarization under fast magic-angle spinning

• Adam Lange

Journal of Magnetic Resonance 2010

Protein refolding is required for assembly of the type three secretion needle

• Adam Lange

Nature Structural & Molecular Biology 2010

Highly preorganized pyrazolate-bridged palladium(ii) and nickel(ii) complexes in bimetallic norbornene polymerization

• Adam Lange

Dalton Transactions 2010

The Native Conformation of the Human VDAC1 N Terminus

• Adam Lange

Angewandte Chemie International Edition 2010

Structural Properties of Pore-Forming Oligomers of α-Synuclein

• Adam Lange

Journal of the American Chemical Society 2009

Low-Power Solid-State NMR Experiments for Resonance Assignment under Fast Magic-Angle Spinning

• Adam Lange

ChemPhysChem 2009

A Combined Solid-State NMR and MD Characterization of the Stability and Dynamics of the HET-s(218-289) Prion in its Amyloid Conformation

• Adam Lange

ChemBioChem 2009

Low-power cross polarization in fast magic-angle spinning NMR experiments

• Adam Lange

Chemical Physics Letters 2009

Infectious and Noninfectious Amyloids of the HET‐s(218–289) Prion Have Different NMR Spectra

• Adam Lange

Angewandte Chemie International Edition 2008

High-Resolution 3D Structure Determination of Kaliotoxin by Solid-State NMR Spectroscopy

• Adam Lange

PLoS ONE 2008

Amyloid Fibrils of the HET-s(218-289) Prion Form a   Solenoid with a Triangular Hydrophobic Core

• Adam Lange

Science 2008

Solid-State NMR Spectroscopy Applied to a Chimeric Potassium Channel in Lipid Bilayers†

• Adam Lange

Journal of the American Chemical Society 2008

The Molecular Mechanism of Toxin-Induced Conformational Changes in a Potassium Channel: Relation to C-Type Inactivation

• Adam Lange

Structure 2008

A structural link between inactivation and block of a K+ channel

• Adam Lange

Nature Structural & Molecular Biology 2008