picture of Peter Schmieder

Dr.

Peter Schmieder

Peter Schmieder was born in 1963 in Frankfurt/Main, Germany. He studied chemistry at the Johann-Wolfgang-Goethe University in Frankfurt, where he obtained his diploma under the supervision of Horst Kessler in 1988. He then moved to the TU Munich together with Prof. Kessler and finished his Ph.D. in 1991. In 1992 he changed to the Department of BCMP at Harvard Medical School and worked with Gerhard Wagner until 1995. In 1995 he became group leader of the NMR-group in the department of NMR-assisted structural biology at the FMP in Berlin, the group was later on named "AG Solution State NMR". His research interests are the development of new NMR-spectroscopic techniques, the structure elucidation of all kinds of molecular systems and the study of their dynamic properties.

  • Head Works Council

Structural Biology


NMR


FMP

Publications

of 10

A new acetylated triterpene saponin from Agrostemma githago L. modulates gene delivery efficiently and shows a high cellular tolerance

  • Clochard, J.
  • Jerz, G.
  • Schmieder, P.
  • Mitdank, H.
  • Tröger, M.
  • Sama, S. (., &
  • Weng, A. (.

International Journal of Pharmaceutics 2020, 589, 119822

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Ambigols from the Cyanobacterium Fischerella ambigua Increase Prodigiosin Production in Serratia spp

  • Chilczuk, T.
  • Monson, R.
  • Schmieder, P.
  • Christov, V.
  • Enke, H.
  • Salmond, G., &
  • Niedermeyer, T. H. J.

ACS Chemical Biology 2020, 15, 2929-2936

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Chemically Induced Vinylphosphonothiolate Electrophiles for Thiol-Thiol Bioconjugations

  • Baumann, A. L.
  • Schwagerus, S.
  • Broi, K.
  • Kemnitz-Hassanin, K.
  • Stieger, C. E.
  • Trieloff, N.
  • Schmieder, P., &
  • Hackenberger, C. P. R.

Journal of the American Chemical Society 2020, 142, 9544-9552

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Crystal structure of Q4D6Q6, a conserved kinetoplastid-specific protein from Trypanosoma cruzi

  • D'Andrea, E. D.
  • Roske, Y.
  • Oliveira, G. A. P.
  • Cremer, N.
  • Diehl, A.
  • Schmieder, P.
  • Heinemann, U.
  • Oschkinat, H., &
  • Pires, J. R.

Journal of Structural Biology 2020, 211, 107536

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Designed nanomolar small-molecule inhibitors of Ena/VASP EVH1 interaction impair invasion and extravasation of breast cancer cells

  • Barone, M.
  • Müller, M.
  • Chiha, S.
  • Ren, J.
  • Albat, D.
  • Soicke, A.
  • Dohmen, S.
  • Klein, M.
  • Bruns, J.
  • Dinther, M.
  • Opitz, R.
  • Lindemann, P.
  • Beerbaum, M.
  • Motzny, K.
  • Roske, Y.
  • Schmieder, P.
  • Volkmer, R.
  • Nazare, M.
  • Heinemann, U.
  • Oschkinat, H.
  • Ten Dijke, P.
  • Schmalz, H. G., &
  • Kühne, R.

Proceedings of the National Academy of Sciences of the United States of America 2020, 117, 29684-29690

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NMR quality control of fragment libraries for screening

  • Sreeramulu, S.
  • Richter, C.
  • Kuehn, T.
  • Azzaoui, K.
  • Blommers, M. J. J.
  • Del Conte, R.
  • Fragai, M.
  • Trieloff, N.
  • Schmieder, P.
  • Nazare, M.
  • Specker, E.
  • Ivanov, V.
  • Oschkinat, H.
  • Banci, L., &
  • Schwalbe, H.

Journal of Biomolecular NMR 2020, 74, 555-563

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pH-Dependent Protonation of Surface Carboxylate Groups in PsbO Enables Local Buffering and Triggers Structural Changes

  • Gerland, L.
  • Friedrich, D.
  • Hopf, L.
  • Donovan, E. J.
  • Wallmann, A.
  • Erdmann, N.
  • Diehl, A.
  • Bommer, M.
  • Buzar, K.
  • Ibrahim, M.
  • Schmieder, P.
  • Dobbek, H.
  • Zouni, A.
  • Bondar, A. N.
  • Dau, H., &
  • Oschkinat, H.

ChemBioChem 2020, 21, 1597-1604

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Sclerotiorin Stabilizes the Assembly of Nonfibrillar Abeta42 Oligomers with Low Toxicity, Seeding Activity, and Beta-sheet Content

  • Wiglenda, T.
  • Groenke, N.
  • Hoffmann, W.
  • Manz, C.
  • Diez, L.
  • Buntru, A.
  • Brusendorf, L.
  • Neuendorf, N.
  • Schnoegl, S.
  • Haenig, C.
  • Schmieder, P.
  • Pagel, K., &
  • Wanker, E. E.

Journal of Molecular Biology 2020, 432, 2080-2098

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Stereochemical Elucidation of Natural Products from Residual Chemical Shift Anisotropies in a Liquid Crystalline Phase

  • Li, X. L.
  • Chi, L. P.
  • Navarro-Vazquez, A.
  • Hwang, S.
  • Schmieder, P.
  • Li, X. M.
  • Li, X.
  • Yang, S. Q.
  • Lei, X. X.
  • Wang, B. G., &
  • Sun, H.

Journal of the American Chemical Society 2020, 142, 2301-2309

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Synthesis and evaluation of non-hydrolyzable phospho-lysine peptide mimics

  • Hauser, A.
  • Poulou, E.
  • Müller, F.
  • Schmieder, P., &
  • Hackenberger, C. P. R.

Chemistry 2020, Online ahead of print, 2326-2331

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Publications

of 5

Enabling adoption of 2D-NMR for the higher order structure assessment of monoclonal antibody therapeutics

  • Brinson, R. G.
  • Marino, J. P.
  • Delaglio, F.
  • Arbogast, L. W.
  • Evans, R. M.
  • Kearsley, A.
  • Gingras, G.
  • Ghasriani, H.
  • Aubin, Y.
  • Pierens, G. K.
  • Jia, X. Y.
  • Mobli, M.
  • Grant, H. G.
  • Keizer, D. W.
  • Schweimer, K.
  • Stahle, J.
  • Widmalm, G.
  • Zartler, E. R.
  • Lawrence, C. W.
  • Reardon, P. N.
  • Cort, J. R.
  • Xu, P.
  • Ni, F.
  • Yanaka, S.
  • Kato, K.
  • Parnham, S. R.
  • Tsao, D.
  • Blomgren, A.
  • Rundlof, T.
  • Trieloff, N.
  • Schmieder, P.
  • Ross, A.
  • Skidmore, K.
  • Chen, K.
  • Keire, D.
  • Freedberg, D. I.
  • Suter-Stahel, T.
  • Wider, G.
  • Ilc, G.
  • Plavec, J.
  • Bradley, S. A.
  • Baldisseri, D. M.
  • Sforca, M. L.
  • Zeri, A. C. D.
  • Wei, J. Y.
  • Szabo, C. M.
  • Amezcua, C. A.
  • Jordan, J. B., &
  • Wikstrom, M.

Mabs 2019, 11, 94-105

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Harnessing C-13-labeled myo-inositol to interrogate inositol phosphate messengers by NMR

  • Harmel, R. K.
  • Puschmann, R.
  • Trung, M. N.
  • Saiardi, A.
  • Schmieder, P., &
  • Fiedler, D.

Chemical Science 2019, 10, 5267-5274

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Metal-triggered conformational reorientation of a self-peptide bound to a disease-associated HLA-B27 subtype

  • Driller, R.
  • Ballaschk, M.
  • Schmieder, P.
  • Uchanska-Ziegler, B.
  • Ziegler, A., &
  • Loll, B.

Journal of Biological Chemistry 2019, 294, 13269-13279

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The companion of cellulose synthase 1 confers salt tolerance through a Tau-like mechanism in plants

  • Kesten, C.
  • Wallmann, A.
  • Schneider, R.
  • McFarlane, H. E.
  • Diehl, A.
  • Khan, G. A.
  • Rossum, B. J.
  • Lampugnani, E. R.
  • Szymanski, W. G.
  • Cremer, N.
  • Schmieder, P.
  • Ford, K. L.
  • Seiter, F.
  • Heazlewood, J. L.
  • Sanchez-Rodriguez, C.
  • Oschkinat, H., &
  • Persson, S.

Nature Communications 2019, 10, 857

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Vinylphosphonites for Staudinger-induced chemoselective peptide cyclization and functionalization

  • Kasper, M. A.
  • Glanz, M.
  • Oder, A.
  • Schmieder, P.
  • Kries, J. P., &
  • Hackenberger, C. P. R.

Chemical Science 2019, 10, 6322-6329

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