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Dr.
+49 30 94793 188
Originally from sunny Philippines, Vince obtained his PhD from Kyoto University, Japan under Prof. Shiroh Futaki funded by the MEXT scholarship. He worked on a peptide-based strategy that combines macropinocytosis induction and endosome release for intracellular delivery of biomacromolecules. Wanting to learn more chemistry, Vince moved to the other side of the world to be a postdoc in the Hackenberger group. He performs microscopy techniques to study the cellular entry mechanisms and to fine-tune the efficacies of cell-penetrating peptides (CPP) and CPP-additives. Away from the lab, he enjoys cooking Asian dishes, drinks, and pub quizzes.
Grafting Hydrophobic Amino Acids Critical for Inhibition of Protein–Protein Interactions on a Cell-Penetrating Peptide Scaffold
Molecular Pharmaceutics 2022
read onlineArtificial Nanocage Formed via Self-Assembly of β-Annulus Peptide for Delivering Biofunctional Proteins into Cell Interiors
Bioconjugate Chemistry 2022
read onlineStearylated Macropinocytosis-Inducing Peptides Facilitating the Cellular Uptake of Small Extracellular Vesicles
Bioconjugate Chemistry 2022
read onlineStructure–Uptake Relationship Study of DABCYL Derivatives Linked to Cyclic Cell‐Penetrating Peptides for Live‐Cell Delivery of Synthetic Proteins
Angewandte Chemie International Edition 2022
read onlineStruktur‐Wirkungsbeziehung von an zyklische Zell‐penetrierende Peptide gebundenen DABCYL‐Derivaten für den Transport von synthetischen Proteinen in lebende Zellen
Angewandte Chemie 2022
read onlineModular solid-phase synthesis of electrophilic cysteine-selective ethynyl-phosphonamidate peptides
Chemical Communications 2022
read onlinePiezo1 activation using Yoda1 inhibits macropinocytosis in A431 human epidermoid carcinoma cells
Scientific Reports 2022
read onlineChemical passports to cross biological borders
Nature Chemistry 2021
read onlineCover Picture: Liquid Droplet Formation and Facile Cytosolic Translocation of IgG in the Presence of Attenuated Cationic Amphiphilic Lytic Peptides (Angew. Chem. Int. Ed. 36/2021)
Angewandte Chemie International Edition 2021
read onlineUse of homoarginine to obtain attenuated cationic membrane lytic peptides.
Bioorganic & medicinal chemistry letters 2021
read onlineLiquid Droplet Formation and Facile Cytosolic Translocation of IgG in the Presence of Attenuated Cationic Amphiphilic Lytic Peptides
Angewandte Chemie 2021
read onlineTitelbild: Liquid Droplet Formation and Facile Cytosolic Translocation of IgG in the Presence of Attenuated Cationic Amphiphilic Lytic Peptides (Angew. Chem. 36/2021)
Angewandte Chemie 2021
read onlineDiscovery of a Macropinocytosis-Inducing Peptide Potentiated by Medium-Mediated Intramolecular Disulfide Formation
Angewandte Chemie - International Edition 2021
read onlinePiezo1 activation using Yoda1 inhibits macropinocytosis and proliferation of cancer cells
Discovery of a Macropinocytosis‐Inducing Peptide Potentiated by Medium‐Mediated Intramolecular Disulfide Formation
Angewandte Chemie 2021
read onlineA facile combinatorial approach to construct a ratiometric fluorescent sensor: application for the real-time sensing of cellular pH changes
Chemical Science 2021
read onlineLiquid Droplet Formation and Facile Cytosolic Translocation of IgG in the Presence of Attenuated Cationic Amphiphilic Lytic Peptides
Angewandte Chemie International Edition 2021
read onlineEnhancing the Activity of Membrane Remodeling Epsin-Peptide by Trimerization
Bioorganic & Medicinal Chemistry Letters 2020
read onlineStimulating Macropinocytosis for Intracellular Nucleic Acid and Protein Delivery: A Combined Strategy with Membrane-Lytic Peptides to Facilitate Endosomal Escape
Bioconjugate Chemistry 2020
read onlinePeptide-assisted intracellular delivery of biomacromolecules
Chemistry Letters 2020
read onlineThe Leibniz-Forschungsinstitut für Molekulare Pharmakologie (FMP) is part of the Forschungsverbund Berlin e.V. (FVB), which legally represents seven non-university research institutes - members of the Leibniz Association - in Berlin.
Leibniz-Forschungsinstitut für Molekulare Pharmakologie im Forschungsverbund Berlin e.V. (FMP)
Campus Berlin-Buch
Robert-Roessle-Str. 10,
13125 Berlin, Germany