Claudia Bohg

Targeting the Membrane‐Embedded Rhomboid Protease GlpG: A Multimodal Strategy for Inhibitor Discovery and Mechanistic Insight

• Claudia Bohg; Yurii Dubanych; Spyridon Kosteletos; Taoran Xiao; Martin Neuenschwander; Tillmann Utesch; Michael Lisurek; Carl Öster; Andreas Oder; Carola Seyffarth; Kathrin Bach; Denise‐Liù Gracias Leone; František Filandr; Marc Wegert; Sascha Lange; Henry Sawczyc; Jens Peter von Kries; Christian P. R. Hackenberger; Edgar Specker; Han Sun; Kvido Stříšovský; Adam Lange

Angewandte Chemie 2026

Targeting the Membrane‐Embedded Rhomboid Protease GlpG: A Multimodal Strategy for Inhibitor Discovery and Mechanistic Insight

• Claudia Bohg; Yurii Dubanych; Spyridon Kosteletos; Taoran Xiao; Martin Neuenschwander; Tillmann Utesch; Michael Lisurek; Carl Öster; Andreas Oder; Carola Seyffarth; Kathrin Bach; Denise‐Liù Gracias Leone; František Filandr; Marc Wegert; Sascha Lange; Henry Sawczyc; Jens Peter von Kries; Christian P. R. Hackenberger; Edgar Specker; Han Sun; Kvido Stříšovský; Adam Lange

Angewandte Chemie International Edition 2026

Lipid-polymer nanoparticles to probe the native-like environment of intramembrane rhomboid protease GlpG and its activity

• Henry Sawczyc; Takashi Tatsuta; Carl Öster; Spyridon Kosteletos; Sascha Lange; Claudia Bohg; Thomas Langer; Adam Lange

Nature Communications 2024

The opening dynamics of the lateral gate regulates the activity of rhomboid proteases

• Claudia Bohg; Carl Öster; Berke Türkaydin; Michael Lisurek; Pascal Sanchez-Carranza; Sascha Lange; Tillmann Utesch; Han Sun; Adam Lange

Science Advances 2023

A combination of solid-state NMR and MD simulations reveals the binding mode of a rhomboid protease inhibitor

• Claudia Bohg; Carl Öster; Tillmann Utesch; Susanne Bischoff; Sascha Lange; Chaowei Shi; Han Sun; Adam Lange

Chemical Science 2021

Structure and Dynamics of the Rhomboid Protease GlpG in Liposomes Studied by Solid-State NMR

• Chaowei Shi; Carl Öster; Claudia Bohg; Longmei Li; Sascha Lange; Veniamin Chevelkov; Adam Lange

Journal of the American Chemical Society 2019