Carl Helmer

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

• Marion Ringel; Carl P. O. Helmer; Shani Zev; Ronja Driller; Emily Buhr; Markus Reinbold; Renana Schwartz; Gabriel Foley; Mikael Boden; Daniel Garbe; Gerhard Schenk; Dan Thomas Major; Bernhard Loll; Thomas Brück

FEBS Letters 2026

Deciphering the evolutionary origin of the enantioselectivity of short-chain dehydrogenases from plants toward 1-borneol

• Jasmin Zuson; Carl P. O. Helmer; Bruno Di Geronimo; Andrea M. Chánique; Katarína Kavčiaková; Rosa Teijeiro-Juiz; Sebastian Brickel; Nuria Ramirez Molina; Ivana Drienovská; Daniel Kracher; Eric A. Gaucher; Shina Caroline Lynn Kamerlin; Bernhard Loll; Robert Kourist

Nature Communications 2026

Deciphering the evolutionary origin of the enantioselectivity of short-chain dehydrogenases from plants toward 1-borneol

• Jasmin Zuson; Carl P.O. Helmer; Bruno Di Geronimo; Andrea M. Chánique; Katarína Kavčiaková; Rosa Teijeiro-Juiz; Sebastian Brickel; Nuria Ramirez Molina; Ivana Drienovská; Daniel Kracher; Eric A. Gaucher; Shina Caroline Lynn Kamerlin; Bernhard Loll; Robert Kourist

How Can the Diterpene Synthase CotB2V80L Alter the Product Profile?

• Stephanie Himpich; Marion Ringel; Renana Schwartz; Nicole Dimos; Ronja Driller; Carl P. O. Helmer; Prashant Kumar Gupta; Martina Haack; Dan Thomas Major; Thomas Brück; Bernhard Loll

ChemCatChem 2024

CryoEM analysis of small plant biocatalysts at sub-2 Å resolution

• Nicole Dimos; Carl P. O. Helmer; Andrea M. Chánique; Markus C. Wahl; Robert Kourist; Tarek Hilal; Bernhard Loll

Acta Crystallographica Section D Structural Biology 2022

A Structural View on the Stereospecificity of Plant Borneol‐Type Dehydrogenases

• Andrea M. Chánique; Nicole Dimos; Ivana Drienovská; Elia Calderini; Mónica P. Pantín; Carl P. O. Helmer; Michael Hofer; Volker Sieber; Loreto P. Parra; Bernhard Loll; Robert Kourist

ChemCatChem 2021

Rapid high-resolution structure analysis of small, biotechnologically relevant enzymes by cryo-electron microscopy

• Nicole Dimos; Carl P.O. Helmer; Andrea M. Chánique; Markus C. Wahl; Robert Kourist; Tarek Hilal; Bernhard Loll