Christian Schmidt

Prion Propagation is Dependent on Key Amino Acids in Charge Cluster 2 within the Prion Protein

• Savroop Bhamra; Parineeta Arora; Szymon W. Manka; Christian Schmidt; Craig Brown; Melissa L.D. Rayner; Peter-Christian Klöhn; Anthony R. Clarke; John Collinge; Parmjit S. Jat

Journal of Molecular Biology 2023

Prion protein monoclonal antibody (PRN100) therapy for Creutzfeldt–Jakob disease: evaluation of a first-in-human treatment programme

• Christian Schmidt

The Lancet Neurology 2022

A high-content neuron imaging assay demonstrates inhibition of prion disease-associated neurotoxicity by an anti-prion protein antibody

• Christian Schmidt

Scientific Reports 2022

Highly infectious prions are not directly neurotoxic

• Christian Schmidt

Proceedings of the National Academy of Sciences 2020

Soluble Aβ aggregates can inhibit prion propagation

• Christian Schmidt

Open Biology 2017

Physical, chemical and kinetic factors affecting prion infectivity

• Christian Schmidt

Prion 2016

A systematic investigation of production of synthetic prions from recombinant prion protein

• Christian Schmidt

Open Biology 2015

Prion neuropathology follows the accumulation of alternate prion protein isoforms after infective titre has peaked

• Christian Schmidt

Nature Communications 2014

In vitro screen of prion disease susceptibility genes using the scrapie cell assay

• Christian Schmidt

Human Molecular Genetics 2014

Global microRNA level regulation of EGFR‐driven cell‐cycle protein network in breast cancer

• Christian Schmidt

Molecular Systems Biology 2012

MicroRNA-520/373 family functions as a tumor suppressor in estrogen receptor negative breast cancer by targeting NF-κB and TGF-β signaling pathways

• Christian Schmidt

Oncogene 2012

An identical, complex TP53 mutation arising independently in two unrelated families with diverse cancer profiles: the complexity of interpreting cancer risk in carriers

• Christian Schmidt

Oncogenesis 2012

Time-Resolved Human Kinome RNAi Screen Identifies a Network Regulating Mitotic-Events as Early Regulators of Cell Proliferation

• Christian Schmidt

PLoS ONE 2011

RNAi-based validation of antibodies for reverse phase protein arrays

• Christian Schmidt

Proteome Science 2010

Increasing the sensitivity of reverse phase protein arrays by antibody-mediated signal amplification

• Christian Schmidt

Proteome Science 2010

Automated production of recombinant human proteins as resource for proteome research

• Christian Schmidt

Proteome Science 2008

Infrared-based protein detection arrays for quantitative proteomics

• Christian Schmidt

PROTEOMICS 2007

The full-ORF clone resource of the German cDNA Consortium

• Christian Schmidt

BMC Genomics 2007

High-Throughput Flow Cytometry–Based Assay to Identify Apoptosis-Inducing Proteins

• Christian Schmidt

SLAS Discovery 2007

Functional Profiling: From Microarrays via Cell-Based Assays to Novel Tumor Relevant Modulators of the Cell Cycle

• Christian Schmidt

Cancer Research 2005

Systematic comparison of surface coatings for protein microarrays

• Christian Schmidt

PROTEOMICS 2005