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Wir betreuen die Kernspinresonanz- bzw. NMR-Spektrometer des FMP und unterstützen Forschende des FMP und anderer Institutionen bei der Nutzung der NMR-Spektroskopie – ob im Festkörper oder in Lösung.
NMR-Spektroskopie macht es möglich, die elektronische Umgebung einzelner Atome und ihrer Wechselwirkungen mit Nachbaratomen zu untersuchen, etwa um Struktur und Dynamik von Molekülen zu bestimmen. Unsere Facility stellt den Forschungsgruppen zwei Open-Access-Spektrometer (300 MHz und 600 MHz) für die Eigennutzung zur Verfügung. Bei komplexeren Problemen arbeiten wir mit den Forschenden zusammen und setzen hierfür unsere mit Kryoköpfen ausgestatteten NMR-Geräte ein. Besonders von Bedeutung ist dabei ein für die 31P-NMR-Spektroskopie geeigneter Kopf, weil die Phosphorylierung von unterschiedlichen Molekülen in den Abteilungen für Chemische Biologie intensiv studiert wird.
Die Festkörper-Spektrometer werden vorrangig von den Abteilungen für Strukturbiologie genutzt, um Strukturen von Membranproteinen oder größeren Aggregaten zu bestimmen. Dazu setzen wir eine große Breite von Feldstärken und Probenköpfen mit unterschiedlichen Probendurchmessern ein. An zwei Spektrometern können zudem DNP-Experimente (Dynamische Kernpolarisation) durchgeführt werden. Daneben erhält die NMR-Facility viele Anfragen von anderen akademischen Gruppen oder von Firmen aus der Nähe des FMP. Diese Anfragen werden nach Möglichkeit entweder durch Kooperationen oder als NMR-Service beantwortet. Darüber hinaus sind wir Teil des von der DFG geförderten G-NMR-Facility-Netzwerks und an der iNEXT (infrastructure for NMR, EM and X-rays for Translational research)-Initiative sowie an weltweiten Ringversuchen beteiligt.
Determination of pKa-Values by NMR with Anett Hauser, Lisa Gerland, Christian Hackenberger, Hartmut Oschkinat
Hunting the eagel killer with Steffen Breinlinger, Timo Niedermeyer
NMR investigation of photochromic compounds with Johannes Broichhagen
Halogen–Aryl-Pi Interactions from Molecular Torsion Balances with Han Sun, Mark Nazare
Determination of pKa-Values by NMR with Anett Hauser, Lisa Gerland, Christian Hackenberger, Hartmut Oschkinat
NMR investigation of the sialyl-pathway with Jakob Gorenflos, Christian Hackenberger
delivered in 1995, purchased with funds from the FMP
new hardware cabinet in 2012
Magnet
Bruker, unshielded, 52 mm bore
Hardware
AV III Console
sample changer (BACS-60)
Probes
5 mm QXI, z-gradient
5mm BBFO, z-Gradient
5 mm TXI, xyz-gradients
5 mm BBI, z-gradient
8 mm TXI, z-gradient
delivered in 1999 as DRX, purchased with funds from the BMBF
upgraded to AV in 2010, cryoplattform replacement in 2011
Magnet
Bruker, shielded, 54 mm bore
Hardware
AV III Console
sample changer (BACS 60)
Probes
5 mm TXI, z-gradient
5 mm QCI Cryoprobe, z-gradient
delivered in 2008, purchased with funds from the FMP
Magnet
Bruker, shielded plus, 54 mm bore
Hardware
AV III Console
sample changer (BACS 60)
Probes
5 mm TCI Cryoprobe, z-grandient
delivered in 1996 as a DMX, purchased with funds from the FMP
upgraded to AV in 2007
Magnet
Magnex, unshielded, 52 mm bore
Hardware
AV III Console
Probes
5 mm TXI, xyz-gradients
8 mm TXI, z-gradient
5 mm TCI Cryoprobe, z-grandient
delivered in 2005, purchased with funds from the FMP, new hardware cabinet in 2016
Magnet
Bruker, shielded, 54 mm bore
Hardware
AVIII Console
sample changer (BACS 120)
Probes
5 mm QNP (13C, 19F, 31P), z-gradient
5mm BBFO, z-Gradient
delivered in 1995, purchased with funds from the FMP
new hardware cabinet in 2012
Magnet
Bruker, unshielded, 52 mm bore
Hardware
AV III Console
sample changer (BACS-60)
Probes
5 mm QXI, z-gradient
5mm BBFO, z-Gradient
5 mm TXI, xyz-gradients
5 mm BBI, z-gradient
8 mm TXI, z-gradient
delivered in 1999 as DRX, purchased with funds from the BMBF
upgraded to AV in 2010, cryoplattform replacement in 2011
Magnet
Bruker, shielded, 54 mm bore
Hardware
AV III Console
sample changer (BACS 60)
Probes
5 mm TXI, z-gradient
5 mm QCI Cryoprobe, z-gradient
delivered in 2008, purchased with funds from the FMP
Magnet
Bruker, shielded plus, 54 mm bore
Hardware
AV III Console
sample changer (BACS 60)
Probes
5 mm TCI Cryoprobe, z-grandient
delivered in 1996 as a DMX, purchased with funds from the FMP
upgraded to AV in 2007
Magnet
Magnex, unshielded, 52 mm bore
Hardware
AV III Console
Probes
5 mm TXI, xyz-gradients
8 mm TXI, z-gradient
5 mm TCI Cryoprobe, z-grandient
delivered in 2005, purchased with funds from the FMP, new hardware cabinet in 2016
Magnet
Bruker, shielded, 54 mm bore
Hardware
AVIII Console
sample changer (BACS 120)
Probes
5 mm QNP (13C, 19F, 31P), z-gradient
5mm BBFO, z-Gradient
delivered in 2007, purchased with funds from the FMP, moved in 2008
upgraded with Gyrotron to enable DNP in 2009
Magnet
Bruker, shielded, 89 mm bore (switched to magnet from other 400 WB in 2008)
Hardware
AV III Console
Probes
2.5 mm MAS HXY
3.2 mm MAS HXY
3.2 mm MAS HXY (Low-T for DNP)
4.0 mm MAS HXY
delivered in 2003, purchased with funds from the BMBF and the FMP
Magnet
Bruker, shielded, 89 mm bore
Hardware
AV III Console
Probes
1.3 mm MAS HXY
1.9 mm MAS HXY
3.2 mm MAS HXY
4.0 mm MAS HXY
delivered in 2005, purchased with funds from the the FMP
Magnet
Bruker, shielded plus, 89 mm bore
Hardware
AV NEO Console
Probes
1.9 mm MAS HCND
3.2 mm MAS HXY
3.2 mm MAS HCN (Efree)
4.0 mm MAS HXY
delivered in 2013, purchased with funds from the FMP upgraded with Gyrotron to enable DNP in 2019
Magnet
Bruker, shielded plus, 89 mm bore
Hardware
AV III Console
Probes
1.3 mm MAS HCND
1.9 mm MAS HXY (Low-T for DNP)
3.2 mm MAS HCN (Efree)
4.0 mm MAS HCN (Efree)
delivered in 2004, purchased with funds from the BMBF and the city of Berlin
Magnet
Bruker, unshielded, 54 mm bore
Hardware
AV NEO Console
Probes
5 mm TXI, z-gradient
1.3 mm MAS (VTX) HCND
1.9 mm MAS HCND
3.2 mm MAS HCN
4.0 mm MAS HCN
delivered in 2007, purchased with funds from the FMP, moved in 2008
upgraded with Gyrotron to enable DNP in 2009
Magnet
Bruker, shielded, 89 mm bore (switched to magnet from other 400 WB in 2008)
Hardware
AV III Console
Probes
2.5 mm MAS HXY
3.2 mm MAS HXY
3.2 mm MAS HXY (Low-T for DNP)
4.0 mm MAS HXY
delivered in 2003, purchased with funds from the BMBF and the FMP
Magnet
Bruker, shielded, 89 mm bore
Hardware
AV III Console
Probes
1.3 mm MAS HXY
1.9 mm MAS HXY
3.2 mm MAS HXY
4.0 mm MAS HXY
delivered in 2005, purchased with funds from the the FMP
Magnet
Bruker, shielded plus, 89 mm bore
Hardware
AV NEO Console
Probes
1.9 mm MAS HCND
3.2 mm MAS HXY
3.2 mm MAS HCN (Efree)
4.0 mm MAS HXY
delivered in 2013, purchased with funds from the FMP upgraded with Gyrotron to enable DNP in 2019
Magnet
Bruker, shielded plus, 89 mm bore
Hardware
AV III Console
Probes
1.3 mm MAS HCND
1.9 mm MAS HXY (Low-T for DNP)
3.2 mm MAS HCN (Efree)
4.0 mm MAS HCN (Efree)
delivered in 2004, purchased with funds from the BMBF and the city of Berlin
Magnet
Bruker, unshielded, 54 mm bore
Hardware
AV NEO Console
Probes
5 mm TXI, z-gradient
1.3 mm MAS (VTX) HCND
1.9 mm MAS HCND
3.2 mm MAS HCN
4.0 mm MAS HCN
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