Chemical Biology

Specific Features of Small Molecules used for Biology

Compounds which interfere with biological functions provide unique application features:

  • temporally:  recovery of function, timelines
  • dosage:       analysis of threshold levels
  • locally:        light inducible release of caged compounds
  • multiple:      application of modulator combinations

Efficient and systematic usage of small molecules as probes for exploring biological systems requires the set up of:

  • well designed compound libraries
  • automation for high throughput screening
  • chemistry for modification and optimization of hits
  • a well designed set of pharmacological profiling routines
  • tools for automated data documentation, analysis and communication