Vor 2013

J. L. Nakamura, C. Phong, E. Pinarbasi, S. C. Kogan, S. Vandenberg, A. E. Horvai, B. A. Faddegon, D. Fiedler, K. M. Shokat, B. T. Houseman, R. Chao, R. O. Pieper, K. Shannon. “Dose-dependent effects of focal fractionated irradiation on secondary malignant neoplasms in Nf1 mutant mice.” Cancer Res. 2011, 71, 106-15.

S. van Wageningen, P. Kemmeren, P. Lijnzaad, T. Margaritis, J. J. Benschop, I. J. de Castro, D. van Leenen, M. J. A. Groot Koerkamp, C. W. Ko, A. J. Miles, N. Brabers, M.O. Brok, T. L. Lenstra, D. Fiedler, L. Fokkens, R. Aldecoa, E. Apweiler, V. Taliadouros, K. Sameith, L. A. L. van de Pasch, S. R. van Hooff, L. V. Bakker, N. J. Krogan, B. Snel, F. C. P. Holstege. “Functional overlap and regulatory links shape genetic interactions between signaling pathways.” Cell 2010, 143, 991-1004. Highlighted in Cell 2010, 143, 867-869. 

S. Bandyopadhyay, M. Mehta, D. Kuo, M. K. Sung, R. Chuang, E. J. Jaehnig, B. Bodenmiller, K. Licon, W. Copeland, M. Shales, D. Fiedler, J. Dutkowski, A. Guénolé, H. van Attikum, K. M. Shokat, R. D. Kolodner, W. K. Huh, R. Aebersold, M. C. Keogh, N. J. Krogan, T. Ideker. “Rewiring of genetic networks in response to DNA damage.” Science 2010, 330, 1385-1389.

P. Beltrao, J. C. Trinidad, D. Fiedler, A. Roguev, W. A. Lim, K. M. Shokat, A. L. Burlingame, N. J. Krogan. “Evolution of phosphoregulation: comparison of phosphorylation patterns across yeast species.” PLoS Biol. 2009, 7, e1000134.

D. Fiedler, H. Braberg, M. Mehta, G. Chechik, G. Cagney, P. Mukherjee, A. C. Silva, M. Shales, S. R. Collins, S. van Wageningen, P. Kemmeren, F. C. P. Holstege, J. S. Weissman, M. Christopher-Keogh, D. Koller, K. M. Shokat, N. J. Krogan. “Functional organization of the S. cerevisiae phosphorylation network.” Cell 2009, 136, 952-963. Cover Picture

T. Okuzumi, D. Fiedler, C. Zhang, D. C. Gray, B. Aizenstein, R. Hoffman, K. M. Shokat. “Inhibitor hijacking of Akt activation.” Nat. Chem. Bio. 2009, 5, 484-493.

H. Wang, B. Kakaradov, S. R. Collins, L. Karotki, D. Fiedler, M. Shales, K. M. Shokat, T. Walther, N. J. Krogan, D. Koller. “A complex-based reconstruction of the S. cerevisiae interactome.“ Mol. Cell. Proteomics 2009, 8, 1361-1381.

L. M. Sly, M. J. Hamilton, E. Kuroda, V. W. Ho, F. L. Antignano, S. L. Omeis, C. J. van Netten-Thomas, D. Wong, H. K. Brugger, O. Williams, M. E. Feldman, B. T. Houseman, D. Fiedler, K. M. Shokat, G. Krystal. “SHIP prevents lipopolysaccharide from triggering an antiviral response in mice.” Blood 2009, 113, 2945-2954.

J. Wang, Z. Knight, D. Fiedler, O. R. Williams, K. M. Shokat, D. Pearce. “Activity of the p110-alpha subunit of phosphatidylinositol-3-kinase is required for activation of epithelial sodium transport.” Am. J. Physiol. 2008, 295, F843-F850. 

T. Tamguney, C. Zhang, D. Fiedler, K. M. Shokat, D. Stokoe. “Analysis of 3-phosphoinositide-dependent kinase-1 signaling and function in ES Cells.” Exp. Cell Res. 2008, 314, 2299-2312.

Graduate

J. S. Mugridge, D. Fiedler, K. N. Raymond. “A Ferrocene-Based Catecholamide Ligand: the Consequences of Ligand Swivel for Directed Supramolecular Self-Assembly.” J. Coord. Chem. 2010, 63, 2779-2789.

M. Pluth, D. Fiedler, R. G. Bergman, K. N. Raymond. “Molecular recognition and self-assembly special feature: Encapsulation and characterization of proton-bound amine homodimers in a water-soluble, self-assembled supramolecular host.” Proc. Nat. Acad. Sci. U.S.A. 2009, 106, 10438-10443.

C. J. Hastings, D. Fiedler, R. G. Bergman, K. N. Raymond. “Aza-Cope rearrangement of propargyl enammonium cations catalyzed by a self-assembled nanozyme.” J. Am. Chem. Soc. 2008, 130, 10977-10983. 

A. V. Davis, D. Fiedler, M. Ziegler, A. Terpin, K. N. Raymond. “Resolution of chiral, tetrahedral M4L6 hosts.” J. Am. Chem. Soc. 2007, 129, 15354-15363. 

V. M. Dong, D. Fiedler, B. Carl, R. G. Bergman, K. N. Raymond. “Molecular recognition and stabilization of iminium ions in water.” J. Am. Chem. Soc. 2006, 128, 14464-14465. Highlighted in Nature 2006, 444, 557. 

D. Fiedler , H. van Halbeek, R. G. Bergman, K. N. Raymond. “ Supramolecular catalysis of unimolecular rearrangements: Substrate scope and mechanistic insights.” J. Am. Chem. Soc. 2006 , 128, 10240-10252. Highlighted in Science 2006, 313, 735.

A. V. Davis, D. Fiedler, G. Seeber, A. Zahl, R. van Eldik, K. N. Raymond. “Guest exchange dynamics in an M4L6 tetrahedral host.” J. Am. Chem. Soc. 2006, 128, 1324-1333. 

D. Fiedler, R. G. Bergman, K. N. Raymond. “Stabilization of reactive organometallic intermediates inside a self-assembled nanoscale host.” Angew. Chem. Int. Ed. 2006, 45, 745-748. 

U. N. Andersen, G. Seeber, D. Fiedler, D. Lin, D. Harris, K. N. Raymond. “Characterization of self-assembled supramolecular host-guest complexes by electrospray ionization mass spectrometry.” J. Am. Soc. Mass. Spectrom. 2006, 17, 292-296.

D. Fiedler, D. H. Leung, R. G. Bergman, K .N. Raymond. “Selective molecular recognition, C-H Bond activation and catalysis in nanoscale reaction vessels.” Acc. Chem. Res. 2005, 38, 349-358.

D. Fiedler , R. G. Bergman, K. N. Raymond. “Supramolecular catalysis of a unimolecular transformation: Aza-Cope rearrangement within a self-assembled host.” Angew. Chem. Int. Ed. 2004, 43, 6748-6751. Cover Picture. Highlighted in Angew. Chem. Int. Ed. 2005, 44, 1000-1002.

D. Fiedler , D. H. Leung, R. G. Bergman, K. N. Raymond. “Enantioselective guest binding and dynamic resolution of cationic ruthenium complexes by a chiral metal-ligand assembly.” J. Am. Chem. Soc. 2004, 126, 3674-3675. 

D. H. Leung, D. Fiedler, R. G. Bergman, K. N. Raymond. “Selective C-H bond activation by a supramolecular host-guest assembly.” Angew. Chem. Int. Ed. 2004, 43, 963-966. 

D. Fiedler, D. Pagliero, J. L. Brumaghim, R. G. Bergman, K. N. Raymond. “Encapsulation of cationic ruthenium complexes into a chiral self-assembled cage.” Inorg. Chem. 2004, 43, 846-848.