Publikationen

Fine‐tuned photochromic sulfonylureas for optical control of beta cell Ca2+ fluxes

Diabetic Medicine, 2023

Design and Evaluation of Phosphonamidate-Linked Exatecan Constructs for Highly Loaded, Stable, and Efficacious Antibody–Drug Conjugates

Molecular Cancer Therapeutics, 2023

Fluorination Influences the Bioisostery of Myo‐Inositol Pyrophosphate Analogs

Chemistry – A European Journal, 2023

Structure–function relationships in protein homorepeats

Current Opinion in Structural Biology, 2023

Rho GTPase signaling and mDia facilitate endocytosis via presynaptic actin

2023

Rho GTPase signaling and mDia facilitate endocytosis via presynaptic actin

2023

Distinct beta-arrestin coupling and intracellular trafficking of metabotropic glutamate receptor homo- and heterodimers

Science Advances, 2023

Orchestrating vesicular and nonvesicular membrane dynamics by intrinsically disordered proteins

EMBO reports, 2023

Elucidating the clandestine behavior of enantiomeric DHPs in calcium channels

Journal of General Physiology, 2023

In Situ Spectroscopic Detection of Large‐Scale Reorientations of Transmembrane Helices During Influenza A M2 Channel Opening**

Angewandte Chemie International Edition, 2023

In situ‐spektroskopische Detektion der weitreichenden Reorientierung von Transmembranhelices während der Öffnung des Influenza A M2‐Kanals**

Angewandte Chemie, 2023

Deciphering histone H4 lysine acetylation and methylation via sortase-mediated semisynthesis

Cell Reports Physical Science, 2023

Structure-Based Design of Xanthine-Imidazopyridines and -Imidazothiazoles as Highly Potent and In Vivo Efficacious Tryptophan Hydroxylase Inhibitors

Journal of Medicinal Chemistry, 2023

Deuteration provides a general strategy to enhance azobenzene-based photopharmacology

2023

An unconventional gatekeeper mutation sensitizes inositol hexakisphosphate kinases to an allosteric inhibitor

eLife, 2023

A design strategy to generate a SARS‐CoV‐2 RBD vaccine that abrogates ACE2 binding and improves neutralizing antibody responses

European Journal of Immunology, 2023

From head to tail - Atomistic mechanism of long-range coupling from the cytosolic sensor domain to the selectivity filter in TREK K2Pchannels

2023

Rho GTPase signaling and mDia facilitate endocytosis via presynaptic actin

2023

An unconventional gatekeeper mutation sensitizes inositol hexakisphosphate kinases to an allosteric inhibitor

eLife, 2023

Diversity of rhodopsin cyclases in zoospore-forming fungi

Proceedings of the National Academy of Sciences, 2023

CB₂R ligands to treat inflammatory diabetes

Open Access Government, 2023

Cell-Surface-Retained Peptide Additives for the Cytosolic Delivery of Functional Proteins

Journal of the American Chemical Society, 2023

Bioinformatics-Guided Discovery of Biaryl-Linked Lasso Peptides

Chemical Science, 2023

Structural Basis for Highly Selective Class II Alpha Phosphoinositide-3-Kinase Inhibition

Journal of Medicinal Chemistry, 2023

Nuclear magnetic resonance/single molecule fluorescence combinations to study dynamic protein systems

Current Opinion in Structural Biology, 2023

An unconventional gatekeeper mutation sensitizes inositol hexakisphosphate kinases to an allosteric inhibitor

2023

Community-developed checklists for publishing images and image analyses

Nature Methods, 2023

Isoform-selective targeting of PI3K: time to consider new opportunities?

Trends in Pharmacological Sciences, 2023

Spatially resolved protein map of intact human cytomegalovirus virions

Nature Microbiology, 2023

Intersectin deficiency impairs cortico-striatal neurotransmission and causes obsessive–compulsive behaviors in mice

Proceedings of the National Academy of Sciences, 2023

OrgaMapper: A robust and easy-to-use workflow for analyzing organelle positioning

2023

Cryo-EM structures of actin binding proteins as tool for drug discovery

Biochemical Pharmacology, 2023

Addressing persistent challenges in digital image analysis of cancerous tissues

2023

CB2R agonists in the clinics: A treasure chest for treating inflammatory diseases

Open Access Government, 2023

The opening dynamics of the lateral gate regulates the activity of rhomboid proteases

Science Advances, 2023

Direct optical measurement of intra-molecular distances down to the Ångström scale

2023

An unconventional gatekeeper mutation sensitizes inositol hexakisphosphate kinases to an allosteric inhibitor

2023

Neuronal endoplasmic reticulum architecture and roles in axonal physiology

Molecular and Cellular Neuroscience, 2023

Structural characterization of human tryptophan hydroxylase 2 reveals that L-Phe is superior to L-Trp as the regulatory domain ligand

Structure, 2023

A Lysosome-Targeted Tetrazine for Organelle-Specific Click-to-Release Chemistry in Antigen Presenting Cells

Journal of the American Chemical Society, 2023

(3+2)‐Cyclization Reactions of Unsaturated Phosphonites with Aldehydes and Thioketones

Chemistry – A European Journal, 2023

Photoswitchable Inhibitors to Optically Control Specific Kinase Activity

ACS Chemical Biology, 2023

In-situ spectroscopic detection of large-scale reorientations of transmembrane α-helices during viroporin channel opening

2023

ClC-7 drives intraphagosomal chloride accumulation to support hydrolase activity and phagosome resolution

Journal of Cell Biology, 2023

Inositol pyrophosphates activate the vacuolar transport chaperone complex in yeast by disrupting a homotypic SPX domain interaction

Nature Communications, 2023

Cesium activates the neurotransmitter receptor for glycine

Frontiers in Molecular Neuroscience, 2023

The Autophagy Nucleation Factor ATG9 Forms Nanoclusters with the HIV-1 Receptor DC-SIGN and Regulates Early Antiviral Autophagy in Human Dendritic Cells

International Journal of Molecular Sciences, 2023

Hypothalamic and brainstem glucose-dependent insulinotropic polypeptide receptor neurons employ distinct mechanisms to affect feeding

JCI Insight, 2023

Itraconazole inhibits endothelial cell migration by disrupting inositol pyrophosphate-dependent focal adhesion dynamics and cytoskeletal remodeling

Biomedicine & Pharmacotherapy, 2023

NMR for Stereochemical Elucidation

Chiral Separations and Stereochemical Elucidation, 2023

Multi-site-specific isotopic labeling accelerates high-resolution structural investigations of pathogenic huntingtin exon-1.

Structure (London, England : 1993), 2023

An unconventional gatekeeper mutation sensitizes inositol hexakisphosphate kinases to an allosteric inhibitor

2023

Data from The INPP4B Tumor Suppressor Modulates EGFR Trafficking and Promotes Triple-Negative Breast Cancer

2023

Supplementary Data from The INPP4B Tumor Suppressor Modulates EGFR Trafficking and Promotes Triple-Negative Breast Cancer

2023

Supplementary Methods from The INPP4B Tumor Suppressor Modulates EGFR Trafficking and Promotes Triple-Negative Breast Cancer

2023

Supplementary Data from The INPP4B Tumor Suppressor Modulates EGFR Trafficking and Promotes Triple-Negative Breast Cancer

2023

Supplementary Methods from The INPP4B Tumor Suppressor Modulates EGFR Trafficking and Promotes Triple-Negative Breast Cancer

2023

TapA acts as specific chaperone in TasA filament formation by strand complementation

Proceedings of the National Academy of Sciences, 2023

Make sustainable changes sustainable

Zenodo, 2023

Discovery of the lanthipeptide curvocidin and structural insights into its trifunctional synthetase CuvL

Angewandte Chemie International Edition, 2023

One Scaffold, Two Conformations: The Ring-Flip of the Messenger InsP₈ Occurs under Cytosolic Conditions

Biomolecules, 2023

Nachhaltige Veränderungen im Labor

BIOspektrum, 2023

Asymmetry and Ion Selectivity Properties of Bacterial Channel NaK Mutants Derived from Ionotropic Glutamate Receptors

Journal of Molecular Biology, 2023

NMDA-receptor-Fc-fusion constructs neutralize anti-NMDA receptor antibodies.

Brain : a journal of neurology, 2023

The structure of pathogenic huntingtin exon 1 defines the bases of its aggregation propensity.

Nature structural & molecular biology, 2023

Real-Time Library Search Increases Cross-Link Identification Depth across All Levels of Sample Complexity

Analytical Chemistry, 2023

Accurate Determination of Motional Amplitudes in Biomolecules by Solid-State NMR

ACS Physical Chemistry Au, 2023

Mechanism of Calcium Permeation in a Glutamate Receptor Ion Channel

Journal of Chemical Information and Modeling, 2023

Small molecule inhibiting microglial nitric oxide release could become a potential treatment for neuroinflammation.

PloS one, 2023

Staudinger Ligation and Reactions – From Bioorthogonal Labeling to Next‐Generation Biopharmaceuticals

Israel Journal of Chemistry, 2023

Chemoselective Labeling and Immobilization of Phosphopeptides with Phosphorimidazolide Reagents

ChemBioChem, 2023

Front Cover: Chemoselective Labeling and Immobilization of Phosphopeptides with Phosphorimidazolide Reagents (ChemBioChem 4/2023)

ChemBioChem, 2023

Nucleolar Architecture Is Modulated by a Small Molecule, the Inositol Pyrophosphate 5-InsP7

Biomolecules, 2023

PI(3,5)P2 Controls the Signaling Activity of Class I PI3K

2023

A versatile Halo- and SNAP-tagged BMP/TGFβ receptor library for quantification of cell surface ligand binding

Communications Biology, 2023

Real-time monitoring of the sialic acid biosynthesis pathway by NMR

Chemical Science, 2023

Compact hydrophilic electrophiles enable highly efficacious high DAR ADCs with excellent in vivo PK profile

Chemical Science, 2023

Endosomal lipid signaling reshapes the endoplasmic reticulum to control mitochondrial function.

Science (New York, N.Y.), 2022

The endocytic TPLATE complex internalizes ubiquitinated plasma membrane cargo

Nature Plants, 2022

Phosphoinositides as membrane organizers

Nature Reviews Molecular Cell Biology, 2022

Unusually Large Effects of Charge‐assisted C−H⋅⋅⋅F Hydrogen Bonds to Anionic Fluorine in Organic Solvents: Computational Study of ¹⁹F NMR Shifts versus Thermochemistry

ChemistryOpen, 2022

Biotin‐Functionalized Block Catiomers as an Active Targeting Approach in Gene Delivery

Macromolecular Materials and Engineering, 2022

Stable Isotopomers of <i>myo-</i>Inositol Uncover a Complex MINPP1-Dependent Inositol Phosphate Network

ACS Central Science, 2022

Ribosome stalling is a signal for metabolic regulation by the ribotoxic stress response

Cell Metabolism, 2022

A General Method to Edit Histone H3 Modifications on Chromatin Via Sortase‐Mediated Metathesis

Angewandte Chemie, 2022

A General Method to Edit Histone H3 Modifications on Chromatin Via Sortase‐Mediated Metathesis

Angewandte Chemie International Edition, 2022

The molecular organization of differentially curved caveolae indicates bendable structural units at the plasma membrane

Nature Communications, 2022

Structure–Uptake Relationship Study of DABCYL Derivatives Linked to Cyclic Cell‐Penetrating Peptides for Live‐Cell Delivery of Synthetic Proteins

Angewandte Chemie International Edition, 2022

Struktur‐Wirkungsbeziehung von an zyklische Zell‐penetrierende Peptide gebundenen DABCYL‐Derivaten für den Transport von synthetischen Proteinen in lebende Zellen

Angewandte Chemie, 2022

Real-time library search increases cross-link identification depth across all levels of sample complexity

2022

Control of Gα q signaling dynamics and GPCR cross-talk by GRKs

Science Advances, 2022

Pyrophosphoproteomics: extensive protein pyrophosphorylation revealed in human cell lines

2022

Hydrogen Peroxide‐Responsive Triggers Based on Borinic Acids: Molecular Insights into the Control of Oxidative Rearrangement

Chemistry – A European Journal, 2022

Phorbolester-activated Munc13-1 and ubMunc13-2 exert opposing effects on dense-core vesicle secretion

eLife, 2022

The sequence context in poly-alanine regions: structure, function and conservation.

Bioinformatics (Oxford, England), 2022

Nucleus-translocated mitochondrial cytochrome c liberates nucleophosmin-sequestered ARF tumor suppressor by changing nucleolar liquid-liquid phase separation.

Nature structural & molecular biology, 2022

Antagonistic control of active surface integrins by myotubularin and phosphatidylinositol 3-kinase C2β in a myotubular myopathy model

Proceedings of the National Academy of Sciences, 2022

DFT‐Guided Discovery of Ethynyl‐Triazolyl‐Phosphinates as Modular Electrophiles for Chemoselective Cysteine Bioconjugation and Profiling

Angewandte Chemie International Edition, 2022

Mutant Phosphodiesterase 3A Protects From Hypertension-Induced Cardiac Damage.

Circulation, 2022

Compound Interaction Screen on a Photoactivatable Cellulose Membrane (CISCM) Identifies Drug Targets

ChemMedChem, 2022

Potential Distribution across Model Membranes

The Journal of Physical Chemistry B, 2022

Probing Factor Xa Protein–Ligand Interactions: Accurate Free Energy Calculations and Experimental Validations of Two Series of High-Affinity Ligands

Journal of Medicinal Chemistry, 2022

Author Correction: QuasAr Odyssey: the origin of fluorescence and its voltage sensitivity in microbial rhodopsins

Nature Communications, 2022

Versatile signaling mechanisms of inositol pyrophosphates

Current Opinion in Chemical Biology, 2022

DFT‐basierte Entdeckung von Ethynyl‐Triazolyl‐Phosphinaten als modulare Elektrophile für die chemoselektive Cystein‐Biokonjugation und Profilierung

Angewandte Chemie, 2022

Back Cover: DFT‐Guided Discovery of Ethynyl‐Triazolyl‐Phosphinates as Modular Electrophiles for Chemoselective Cysteine Bioconjugation and Profiling (Angew. Chem. Int. Ed. 41/2022)

Angewandte Chemie International Edition, 2022

Rücktitelbild: DFT‐basierte Entdeckung von Ethynyl‐Triazolyl‐Phosphinaten als modulare Elektrophile für die chemoselektive Cystein‐Biokonjugation und Profilierung (Angew. Chem. 41/2022)

Angewandte Chemie, 2022

Development of selective inhibitors of phosphatidylinositol 3-kinase C2α.

Nature chemical biology, 2022

Identification of the Allosteric Binding Site for Thiazolopyrimidine on the C-Type Lectin Langerin.

ACS chemical biology, 2022

QuasAr Odyssey: the origin of fluorescence and its voltage sensitivity in microbial rhodopsins

Nature Communications, 2022

Synthetic α‐Helical Peptides as Potential Inhibitors of the ACE2 SARS‐CoV‐2 Interaction

ChemBioChem, 2022

Inositol Pyrophosphate-Controlled Kinetochore Architecture and Mitotic Entry in <i>S. pombe</i>

Journal of Fungi, 2022

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

Life science alliance, 2022

Nanoscale segregation of channel and barrier claudins enables paracellular ion flux

Nature Communications, 2022

Gram-Scale Asymmetric Synthesis of Fluorinated Amino Acids Using a Chiral Nickel(II) Complex

The Journal of Organic Chemistry, 2022

Donor manipulation for constructing a pH sensing thermally activated delayed fluorescent probe to detect alkaliphiles

Talanta, 2022

Renal Deletion of LRRC8/VRAC Channels Induces Proximal Tubulopathy

Journal of the American Society of Nephrology, 2022

Stable isotopomers of myo-inositol to uncover the complex MINPP1-dependent inositol phosphate network

2022

An examination of the divergent spatiotemporal signaling of GLP-1R versus GIPR in pancreatic beta cells

2022

Alternative Benzoxazole Assembly Discovered in Anaerobic Bacteria Provides Access to Privileged Heterocyclic Scaffold

Angewandte Chemie International Edition, 2022

Alternative Benzoxazole Assembly Discovered in Anaerobic Bacteria Provides Access to Privileged Heterocyclic Scaffold

Angewandte Chemie, 2022

Structure-Based Design of Xanthine-Benzimidazole Derivatives as Novel and Potent Tryptophan Hydroxylase Inhibitors

Journal of Medicinal Chemistry, 2022

Mechanism of threonine ADP-ribosylation of F-actin by a Tc toxin

Nature Communications, 2022

Defective lipid signalling caused by mutations in PIK3C2B underlies focal epilepsy.

Brain : a journal of neurology, 2022

PP2A is activated by cytochrome <i>c</i> upon formation of a diffuse encounter complex with SET/TAF-Iβ.

Computational and structural biotechnology journal, 2022

Correction to: Establishment of Proximity-Dependent Biotinylation Approaches in Different Plant Model Systems

The Plant Cell, 2022

Local synthesis of the phosphatidylinositol-3,4-bisphosphate lipid drives focal adhesion turnover.

Developmental cell, 2022

An LPAR _<b>5</b> -antagonist that reduces nociception and increases pruriception.

Frontiers in pain research (Lausanne, Switzerland), 2022

Weizhouochrones: Gorgonian-Derived Symmetric Dimers and Their Structure Elucidation Using Anisotropic NMR Combined with DP4+ Probability and CASE-3D

Journal of Natural Products, 2022

Design and Functional Analysis of Heterobifunctional Multivalent Phage Capsid Inhibitors Blocking the Entry of Influenza Virus

Bioconjugate Chemistry, 2022

ZAKβ is activated by cellular compression and mediates contraction‐induced MAP kinase signaling in skeletal muscle

The EMBO Journal, 2022

Proton-gated anion transport governs macropinosome shrinkage

Nature Cell Biology, 2022

<i>Arabidopsis</i> PFA-DSP-Type Phosphohydrolases Target Specific Inositol Pyrophosphate Messengers

Biochemistry, 2022

A Simple Fluorescence Affinity Assay to Decipher Uranyl‐Binding to Native Proteins

Angewandte Chemie, 2022

A Simple Fluorescence Affinity Assay to Decipher Uranyl‐Binding to Native Proteins

Angewandte Chemie International Edition, 2022

Mechanism of threonine ADP-ribosylation of F-actin by a Tc toxin

2022

Selective endocytosis of Ca 2+ -permeable AMPARs by the Alzheimer’s disease risk factor CALM bidirectionally controls synaptic plasticity

Science Advances, 2022

Stearylated Macropinocytosis-Inducing Peptides Facilitating the Cellular Uptake of Small Extracellular Vesicles

Bioconjugate Chemistry, 2022

Cross-link assisted spatial proteomics to map sub-organelle proteomes and membrane protein topology

2022

Reverse-Design toward Optimized Labeled Chemical Probes – Examples from the Endocannabinoid System

CHIMIA, 2022

Visualisierung endogener Proteine in ihrer natürlichen Umgebung

BIOspektrum, 2022

Expanded LUXendin Color Palette for GLP1R Detection and Visualization In Vitro and In Vivo

JACS Au, 2022

Detection of cannabinoid receptor type 2 in native cells and zebrafish with a highly potent, cell-permeable fluorescent probe.

Chemical science, 2022

Piezo1 activation using Yoda1 inhibits macropinocytosis in A431 human epidermoid carcinoma cells

Scientific Reports, 2022

Atomistic insight into the essential binding event of ACE2-derived peptides to the SARS-CoV-2 spike protein

Biological Chemistry, 2022

Restoration of high-sensitivity patterned vision in motion with an engineered light-gated G protein-coupled receptor

2022

Advances in tethered photopharmacology for precise optical control of signaling proteins

Current Opinion in Pharmacology, 2022

Site-specific N-glycan profiles of α₅ β₁ integrin from rat liver.

Biology of the cell, 2022

Endosomal phosphatidylinositol 3-phosphate controls synaptic vesicle cycling and neurotransmission.

The EMBO journal, 2022

Mechanism underlying a risk gene in neurodegeneration

Nature, 2022

A Membrane‐Permeable and Immobilized Metal Affinity Chromatography (IMAC) Enrichable Cross‐Linking Reagent to Advance In Vivo Cross‐Linking Mass Spectrometry

Angewandte Chemie International Edition, 2022

Structural basis of phosphatidylinositol 3-kinase C2α function

Nature Structural & Molecular Biology, 2022

Bis‐ethynylphosphonamidates as an Modular Conjugation Platform to Generate Multi‐Functional Protein‐ and Antibody‐Drug‐Conjugates

European Journal of Organic Chemistry, 2022

GLP1R Attenuates Sympathetic Response to High Glucose via Carotid Body Inhibition

Circulation Research, 2022

A versatile Halo- and SNAP-tagged BMP/TGFβ receptor library for quantification of cell surface ligand binding

2022

Direct Detection of Bound Ammonium Ions in the Selectivity Filter of Ion Channels by Solid-State NMR

Journal of the American Chemical Society, 2022

Review of Biochemical analysis of deacetylase activity of rice sirtuin OsSRT1, a class IV member in plants

Zenodo, 2022

Inositol triphosphate-triggered calcium release from the endoplasmic reticulum induces lysosome biogenesis via TFEB/TFE3.

The Journal of biological chemistry, 2022

Neuronal Autophagy Regulates Presynaptic Neurotransmission by Controlling the Axonal Endoplasmic Reticulum.

Neuron, 2022

Proteomic characterization of isolated Arabidopsis clathrin-coated vesicles reveals evolutionarily conserved and plant-specific components.

The Plant cell, 2022

Grafting Hydrophobic Amino Acids Critical for Inhibition of Protein–Protein Interactions on a Cell-Penetrating Peptide Scaffold

Molecular Pharmaceutics, 2022

Artificial Nanocage Formed via Self-Assembly of β-Annulus Peptide for Delivering Biofunctional Proteins into Cell Interiors

Bioconjugate Chemistry, 2022

Gating choreography and mechanism of the human proton-activated chloride channel ASOR

Science Advances, 2022

Phosphoinositide Conversion Inactivates R-RAS and Drives Metastases in Breast Cancer.

Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2022

Clathrin-independent endocytic retrieval of SV proteins mediated by the clathrin adaptor AP-2 at mammalian central synapses.

eLife, 2022

Inositol Triphosphate Signaling Triggers Lysosome Biogenesis Via Calcium Release from Endoplasmic Reticulum Stores

Contact, 2022

Systematic Evaluation of Modern Density Functional Methods for the Computation of NMR Shifts of 3d Transition-Metal Nuclei

Journal of Chemical Theory and Computation, 2022

Rational Design of Highly Potent, Selective, and Bioavailable SGK1 Protein Kinase Inhibitors for the Treatment of Osteoarthritis

Journal of Medicinal Chemistry, 2022

Major tail proteins of bacteriophages of the order Caudovirales

Journal of Biological Chemistry, 2022

Pharmacological tools to investigate inositol polyphosphate kinases – Enzymes of increasing therapeutic relevance

Advances in Biological Regulation, 2022

Aurora Kinase A Is Involved in Controlling the Localization of Aquaporin-2 in Renal Principal Cells

International Journal of Molecular Sciences, 2022

Investigation of a potential electrogenic transport-system for myo-inositol in the small intestine of laying hens

British Poultry Science, 2022

Programmable alignment media from self-assembled oligopeptide amphiphiles for the measurement of independent sets of residual dipolar couplings in organic solvents

Chemical Science, 2022

Sulfonated red and far-red rhodamines to visualize SNAP- and Halo-tagged cell surface proteins

Organic & Biomolecular Chemistry, 2022

Fluorine-induced polarity increases inhibitory activity of BPTI towards chymotrypsin

RSC Chemical Biology, 2022

Modular solid-phase synthesis of electrophilic cysteine-selective ethynyl-phosphonamidate peptides

Chemical Communications, 2022

Enzyme self-label-bound ATTO700 in single-molecule and super-resolution microscopy

Chemical Communications, 2022

N-Methyl deuterated rhodamines for protein labelling in sensitive fluorescence microscopy

Chemical Science, 2022

PI(3,4)P2-mediated cytokinetic abscission prevents early senescence and cataract formation

Science, 2021

Evaluation of borinic acids as new, fast hydrogen peroxide–responsive triggers

Proceedings of the National Academy of Sciences, 2021

Progress in Free Energy Perturbation: Options for Evolving Fragments

Drug Discovery Today: Technologies, 2021

The molecular mechanisms mediating class II PI 3‐kinase function in cell physiology

The FEBS Journal, 2021

Extended Benchmark Set of Main-Group Nuclear Shielding Constants and NMR Chemical Shifts and Its Use to Evaluate Modern DFT Methods

Journal of Chemical Theory and Computation, 2021

Development of a 1,2,4-Triazole-Based Lead Tankyrase Inhibitor: Part II.

Journal of medicinal chemistry, 2021

Higher harmonics in complex plasmas with alternating screening

Physical Review Research, 2021

Reagents and models for detecting endogenous GLP1R and GIPR

eBioMedicine, 2021

Numaswitch: an efficient high-titer expression platform to produce peptides and small proteins

AMB Express, 2021

A Remote Secondary Binding Pocket Promotes Heteromultivalent Targeting of DC-SIGN

Journal of the American Chemical Society, 2021

SNAP-tag-enabled super-resolution imaging reveals constitutive and agonist-dependent trafficking of GPR56 in pancreatic β-cells

Molecular Metabolism, 2021

ITPK1 is an InsP6/ADP phosphotransferase that controls phosphate signaling in Arabidopsis

Molecular Plant, 2021

Labkit: Labeling and Segmentation Toolkit for Big Image Data

2021

Munc13-1 is a Ca2+-phospholipid-dependent vesicle priming hub that shapes synaptic short-term plasticity and enables sustained neurotransmission

Neuron, 2021

Enhanced Properties of a Benzimidazole Benzylpyrazole Lysine Demethylase Inhibitor: Mechanism-of-Action, Binding Site Analysis, and Activity in Cellular Models of Prostate Cancer

Journal of Medicinal Chemistry, 2021

Pentafluorosulfanyl (SF₅) as a Superior ¹⁹F Magnetic Resonance Reporter Group: Signal Detection and Biological Activity of Teriflunomide Derivatives.

ACS sensors, 2021

Structural and compositional diversity in the kainate receptor family

Cell Reports, 2021

Structural evidence for visual arrestin priming via complexation of phosphoinositols

Structure, 2021

Cover Picture: Liquid Droplet Formation and Facile Cytosolic Translocation of IgG in the Presence of Attenuated Cationic Amphiphilic Lytic Peptides (Angew. Chem. Int. Ed. 36/2021)

Angewandte Chemie International Edition, 2021

Liquid Droplet Formation and Facile Cytosolic Translocation of IgG in the Presence of Attenuated Cationic Amphiphilic Lytic Peptides

Angewandte Chemie, 2021

Titelbild: Liquid Droplet Formation and Facile Cytosolic Translocation of IgG in the Presence of Attenuated Cationic Amphiphilic Lytic Peptides (Angew. Chem. 36/2021)

Angewandte Chemie, 2021

Liquid Droplet Formation and Facile Cytosolic Translocation of IgG in the Presence of Attenuated Cationic Amphiphilic Lytic Peptides

Angewandte Chemie International Edition, 2021

Zellpermeable Nanobodys ermöglichen Zwei‐Farben‐Superauflösungsmikroskopie in lebenden, nicht transfizierten Zellen

Angewandte Chemie, 2021

Cell‐Permeable Nanobodies Allow Dual‐Color Super‐Resolution Microscopy in Untransfected Living Cells

Angewandte Chemie International Edition, 2021

Using Biotinylated <i>myo</i>-Inositol Hexakisphosphate to Investigate Inositol Pyrophosphate–Protein Interactions with Surface-Based Biosensors

Biochemistry, 2021

Evidence of sulfur mustard poisoning by detection of the albumin‐derived dipeptide biomarker C(‐HETE)P after nicotinylation

Drug Testing and Analysis, 2021

Sequential in vivo labeling of insulin secretory granule pools in INS - SNAP transgenic pigs

Proceedings of the National Academy of Sciences, 2021

Regulation of the Golgi Apparatus by p38 and JNK Kinases during Cellular Stress Responses

International Journal of Molecular Sciences, 2021

Conversion of dietary inositol into propionate and acetate by commensal Anaerostipes associates with host health

Nature Communications, 2021

How solvent-free crosslinking conditions alter the chemistry and topology of hemiketal based polymer networks

Polymer, 2021

Identification of disease-relevant modulators of the SHH pathway in the developing brain.

Development (Cambridge, England), 2021

Alkylated albumin-derived dipeptide C(-HETE)P derivatized by propionic anhydride as a biomarker for the verification of poisoning with sulfur mustard

Analytical and Bioanalytical Chemistry, 2021

En route to dynamic life processes by SNARE-mediated fusion of polymer and hybrid membranes

Nature Communications, 2021

Topical inflammasome inhibition with disulfiram prevents irritant contact dermatitis.

Clinical and translational allergy, 2021

Diethynyl Phosphinates for Cysteine‐Selective Protein Labeling and Disulfide Rebridging

Angewandte Chemie International Edition, 2021

Diethinylphosphinate für die Cystein‐selektive Proteinmarkierung und Disulfid‐Verbrückung

Angewandte Chemie, 2021

Chemical Biology Tools To Investigate Malaria Parasites

ChemBioChem, 2021

Sodium Ions Do Not Stabilize the Selectivity Filter of a Potassium Channel

Journal of Molecular Biology, 2021

A mechanochemical mechanism couples exocrine secretion to endocytic membrane retrieval.

Developmental cell, 2021

Robust principal component analysis‐based prediction of protein‐protein interaction hot spots

Proteins: Structure, Function, and Bioinformatics, 2021

Bicyclic β‐Sheet Mimetics that Target the Transcriptional Coactivator β‐Catenin and Inhibit Wnt Signaling

Angewandte Chemie, 2021

Clathrin-independent endocytic retrieval of SV proteins mediated by the clathrin adaptor AP-2 at mammalian central synapses

2021

Cellular uptake of large biomolecules enabled by cell-surface-reactive cell-penetrating peptide additives

Nature Chemistry, 2021

Automatisierte Glykan‐Assemblierung 19F‐markierter Glykansonden ermöglicht Hochdurchsatz‐NMR‐Untersuchungen von Protein‐Glykan‐Interaktionen

Angewandte Chemie, 2021

Automated Glycan Assembly of 19F‐labeled Glycan Probes Enables High‐Throughput NMR Studies of Protein–Glycan Interactions

Angewandte Chemie International Edition, 2021

Evidence of exposure to organophosphorus toxicants by detection of the propionylated butyrylcholinesterase-derived nonapeptide-adduct as a novel biomarker

Forensic Science International, 2021

Tight docking of membranes before fusion represents a metastable state with unique properties

Nature Communications, 2021

Inositol triphosphate-triggered calcium release blocks lipid exchange at endoplasmic reticulum-Golgi contact sites

Nature Communications, 2021

Structural plasticity of the selectivity filter in a nonselective ion channel

IUCrJ, 2021

Distinct EH domains of the endocytic TPLATE complex confer lipid and protein binding

Nature Communications, 2021

Rab2 regulates presynaptic precursor vesicle biogenesis at the trans-Golgi

Journal of Cell Biology, 2021

NMR of natural products

Magnetic Resonance in Chemistry, 2021

Piezo1 activation using Yoda1 inhibits macropinocytosis and proliferation of cancer cells

2021

Discovery of a Macropinocytosis‐Inducing Peptide Potentiated by Medium‐Mediated Intramolecular Disulfide Formation

Angewandte Chemie, 2021

Cannabinoid receptor type 2 ligands: an analysis of granted patents since 2010

Pharmaceutical Patent Analyst, 2021

Conditional destabilization of the TPLATE complex impairs endocytic internalization

Proceedings of the National Academy of Sciences, 2021

Neuronal autophagy controls the axonal endoplasmic reticulum to regulate neurotransmission in healthy neurons

Autophagy, 2021

Implementation and Validation of Local Hybrid Functionals with Calibrated Exchange-Energy Densities for Nuclear Shielding Constants

The Journal of Physical Chemistry A, 2021

DOTAM-Based, Targeted, Activatable Fluorescent Probes for the Highly Sensitive and Selective Detection of Cancer Cells

Bioconjugate Chemistry, 2021

XlinkCyNET: A Cytoscape Application for Visualization of Protein Interaction Networks Based on Cross-Linking Mass Spectrometry Identifications

Journal of Proteome Research, 2021

eIF5A hypusination, boosted by dietary spermidine, protects from premature brain aging and mitochondrial dysfunction

Cell Reports, 2021

Cover Feature: Site‐Specific Antibody Fragment Conjugates for Reversible Staining in Fluorescence Microscopy (7/2021)

ChemBioChem, 2021

Acylation of the incretin peptide exendin-4 directly impacts GLP-1 receptor signalling and trafficking

2021

Evaluation of efficacy- versus affinity-driven agonism with biased GLP-1R ligands P5 and exendin-F1

2021

Differences in interactions between transmembrane domains tune the activation of metabotropic glutamate receptors

eLife, 2021

Sequential in vivo labeling of insulin secretory granule pools in INS-SNAP transgenic pigs

2021

Liquid-like protein assemblies initiate endocytosis

Nature Cell Biology, 2021

Mechanism of synaptic protein turnover and its regulation by neuronal activity.

Current opinion in neurobiology, 2021

Dysregulation of myelin synthesis and actomyosin function underlies aberrant myelin in CMT4B1 neuropathy.

Proceedings of the National Academy of Sciences of the United States of America, 2021

Similarities and Differences among Protein Dynamics Studied by Variable Temperature Nuclear Magnetic Resonance Relaxation

The Journal of Physical Chemistry B, 2021

Effect of the Current Dependence of Tau-Dependent Exchange-Correlation Functionals on Nuclear Shielding Calculations

Journal of Chemical Theory and Computation, 2021

Hunting the eagle killer: A cyanobacterial neurotoxin causes vacuolar myelinopathy

Science, 2021

Use of homoarginine to obtain attenuated cationic membrane lytic peptides.

Bioorganic & medicinal chemistry letters, 2021

Novel amyloid-beta pathology C. elegans model reveals distinct neurons as seeds of pathogenicity

Progress in Neurobiology, 2021

Affinity enrichment and identification of inositol poly- and pyrophosphate interactomes

STAR Protocols, 2021

Unique Properties of Tightly Docked Membranes Prior to their Fusion

Biophysical Journal, 2021

Effective image visualization for publications – a workflow using open access tools and concepts [version 2; peer review: 2 approved]

2021

Molecular architecture of the endocytic TPLATE complex

Science Advances, 2021

Photocaged Hoechst Enables Subnuclear Visualization and Cell Selective Staining of DNA in vivo

ChemBioChem, 2021

Nonselective cation permeation in an AMPA-type glutamate receptor

Proceedings of the National Academy of Sciences, 2021

Synthesis and Evaluation of Non‐Hydrolyzable Phospho‐Lysine Peptide Mimics

Chemistry – A European Journal, 2021

Synthesis and Evaluation of Non‐Hydrolyzable Phospho‐Lysine Peptide Mimics

Chemistry – A European Journal, 2021

Front Cover: Synthesis and Evaluation of Non‐Hydrolyzable Phospho‐Lysine Peptide Mimics (Chem. Eur. J. 7/2021)

Chemistry – A European Journal, 2021

Differences in interactions between transmembrane domains tune the activation of metabotropic glutamate receptors

2021

The axonal endolysosomal and autophagic systems.

Journal of neurochemistry, 2021

Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)¹.

Autophagy, 2021

Proposed mechanism for regulation of H₂ O₂ -induced programmed cell death in plants by binding of cytochrome c to 14-3-3 proteins.

The Plant journal : for cell and molecular biology, 2021

Functional Imaging Using Fluorine (¹⁹F) MR Methods: Basic Concepts.

Methods in molecular biology (Clifton, N.J.), 2021

<i>In vivo</i> detection of teriflunomide-derived fluorine signal during neuroinflammation using fluorine MR spectroscopy.

Theranostics, 2021

Dissecting the activation of insulin degrading enzyme by inositol pyrophosphates and their bisphosphonate analogs

Chemical Science, 2021

Chemical passports to cross biological borders

Nature Chemistry, 2021

Discovery of a Macropinocytosis-Inducing Peptide Potentiated by Medium-Mediated Intramolecular Disulfide Formation

Angewandte Chemie - International Edition, 2021

A facile combinatorial approach to construct a ratiometric fluorescent sensor: application for the real-time sensing of cellular pH changes

Chemical Science, 2021

A combination of solid-state NMR and MD simulations reveals the binding mode of a rhomboid protease inhibitor

Chemical Science, 2021

A silyl ether-protected building block for O-GlcNAcylated peptide synthesis to enable one-pot acidic deprotection

Organic & Biomolecular Chemistry, 2021

The mechanism behind enhanced reactivity of unsaturated phosphorus(v) electrophiles towards thiols

Chemical Science, 2021

Discovery, X-ray structure and CPP-conjugation enabled uptake of p53/MDM2 macrocyclic peptide inhibitors

RSC Chemical Biology, 2021

Long-term in vivo imaging reveals tumor-specific dissemination and captures host tumor interaction in zebrafish xenografts

Scientific Reports, 2020

A Golgi-associated lipid kinase controls peripheral nerve myelination

Proceedings of the National Academy of Sciences, 2020

Cryo-EM structure of the volume-regulated anion channel LRRC8D isoform identifies features important for substrate permeation

Communications Biology, 2020

A recurrent gain-of-function mutation in CLCN6, encoding the ClC-6 Cl-/H+-exchanger, causes early-onset neurodegeneration

2020

Unusual mode of dimerization of retinitis pigmentosa-associated F220C rhodopsin

2020

2020 ASCB Annual Meeting abstracts.

Molecular biology of the cell, 2020

Differential diffusional properties in loose and tight docking prior to membrane fusion.

Biophysical journal, 2020

Effective image visualization for publications – a workflow using open access tools and concepts

F1000Research, 2020

Neuronal Autophagy Regulates Presynaptic Neurotransmission by Controlling the Axonal Endoplasmic Reticulum.

Neuron, 2020

Establishment of Proximity-Dependent Biotinylation Approaches in Different Plant Model Systems

The Plant Cell, 2020

Diverse chemotypes drive biased signaling by cannabinoid receptors

2020

Designed nanomolar small-molecule inhibitors of Ena/VASP EVH1 interaction impair invasion and extravasation of breast cancer cells.

Proceedings of the National Academy of Sciences of the United States of America, 2020

From Pyrazolones to Azaindoles: Evolution of Active-Site SHP2 Inhibitors Based on Scaffold Hopping and Bioisosteric Replacement.

Journal of medicinal chemistry, 2020

Architecture of the flexible tail tube of bacteriophage SPP1

Nature Communications, 2020

Adduct of the blistering warfare agent sesquimustard with human serum albumin and its mass spectrometric identification for biomedical verification of exposure

Analytical and Bioanalytical Chemistry, 2020

Cellular basis of ClC-2 Cl- channel-related brain and testis pathologies.

The Journal of biological chemistry, 2020

Ligand-Specific Factors Influencing GLP-1 Receptor Post-Endocytic Trafficking and Degradation in Pancreatic Beta Cells

International Journal of Molecular Sciences, 2020

A Presynaptic Perspective on Transport and Assembly Mechanisms for Synapse Formation.

Neuron, 2020

Robust Cell-Free Expression of Sub-Pathological and Pathological Huntingtin Exon-1 for NMR Studies. General Approaches for the Isotopic Labeling of Low-Complexity Proteins

Biomolecules, 2020

Ramping up the autophagy-lysosome system to cope with osmotic stress

Autophagy, 2020

Nuclear Spin–Spin Couplings: Efficient Evaluation of Exact Exchange and Extension to Local Hybrid Functionals

The Journal of Physical Chemistry A, 2020

Photohormones Enable Optical Control of the Peroxisome Proliferator-Activated Receptor γ (PPARγ)

Journal of Medicinal Chemistry, 2020

IP7-SPX Domain Interaction Controls Fungal Virulence by Stabilizing Phosphate Signaling Machinery

mBio, 2020

The inositol pyrophosphate 5-InsP 7 drives sodium-potassium pump degradation by relieving an autoinhibitory domain of PI3K p85α

Science Advances, 2020

Endocytosis of BRASSINOSTEROID INSENSITIVE1 is Partly Driven by a Canonical Tyrosine-based Motif.

The Plant cell, 2020

Measurement of Residual Dipolar Couplings of Organic Molecules in Multiple Solvent Systems Using a Liquid‐Crystalline‐Based Medium

Angewandte Chemie International Edition, 2020

Measurement of Residual Dipolar Couplings of Organic Molecules in Multiple Solvent Systems Using a Liquid‐Crystalline‐Based Medium

Angewandte Chemie, 2020

Improved Access to Organo‐Soluble Di‐ and Tetrafluoridochlorate(I)/(III) Salts

Angewandte Chemie International Edition, 2020

Development of High-Specificity Fluorescent Probes to Enable Cannabinoid Type 2 Receptor Studies in Living Cells.

Journal of the American Chemical Society, 2020

A Palladium-Catalyzed Domino Reaction To Access 3-Amino-2H-indazoles from Hydrazines and 2-Halobenzonitriles

Organic Letters, 2020

Melting, freezing, and dynamics of two-dimensional dipole systems in screening bulk media

Physical Review E, 2020

Avoiding ventilator-associated pneumonia: Curcumin-functionalized endotracheal tube and photodynamic action

Proceedings of the National Academy of Sciences, 2020

Delivery of myo‐Inositol Hexakisphosphate to the Cell Nucleus with a Proline‐Based Cell‐Penetrating Peptide

Angewandte Chemie, 2020

Delivery of myo‐Inositol Hexakisphosphate to the Cell Nucleus with a Proline‐Based Cell‐Penetrating Peptide

Angewandte Chemie International Edition, 2020

Endocytosis in the adaptation to cellular stress.

Cell stress, 2020

The INPP4B Tumor Suppressor Modulates EGFR Trafficking and Promotes Triple-Negative Breast Cancer

Cancer Discovery, 2020

Fluorogenic Bifunctional trans‐Cyclooctenes as Efficient Tools for Investigating Click‐to‐Release Kinetics

Chemistry – A European Journal, 2020

Deuterated rhodamines for protein labelling in nanoscopy

2020

Triplexed Affinity Reagents to Sample the Mammalian Inositol Pyrophosphate Interactome

Cell Chemical Biology, 2020

InsP 7 is a small-molecule regulator of NUDT3-mediated mRNA decapping and processing-body dynamics

Proceedings of the National Academy of Sciences, 2020

Inositol triphosphate-triggered calcium release blocks lipid exchange at endoplasmic reticulum-Golgi contact sites

2020

Interrogating surface <i>versus</i> intracellular transmembrane receptor populations using cell-impermeable SNAP-tag substrates.

Chemical science, 2020

Innentitelbild: Pigmentierungschemie und radikalbasierter Kollagenabbau bei Alkaptonurie und Arthrose (Angew. Chem. 29/2020)

Angewandte Chemie, 2020

Pigmentation Chemistry and Radical‐Based Collagen Degradation in Alkaptonuria and Osteoarthritic Cartilage

Angewandte Chemie International Edition, 2020

Pigmentierungschemie und radikalbasierter Kollagenabbau bei Alkaptonurie und Arthrose

Angewandte Chemie, 2020

Inside Cover: Pigmentation Chemistry and Radical‐Based Collagen Degradation in Alkaptonuria and Osteoarthritic Cartilage (Angew. Chem. Int. Ed. 29/2020)

Angewandte Chemie International Edition, 2020

Endocytic regulation of cellular ion homeostasis controls lysosome biogenesis

Nature Cell Biology, 2020

Revealing cytotoxic substructures in molecules using deep learning

Journal of Computer-Aided Molecular Design, 2020

RIM-binding protein couples synaptic vesicle recruitment to release sites

Journal of Cell Biology, 2020

Local externalization of phosphatidylserine mediates developmental synaptic pruning by microglia

The EMBO Journal, 2020

Glycan-dependent cell adhesion mechanism of Tc toxins

Nature Communications, 2020

Phosphodiesterase 3A and Arterial Hypertension.

Circulation, 2020

Rab35-regulated lipid turnover by myotubularins represses mTORC1 activity and controls myelin growth

Nature Communications, 2020

NMR quality control of fragment libraries for screening

Journal of Biomolecular NMR, 2020

Conditionally Controlling Human TLR2 Activity via Trans-Cyclooctene Caged Ligands

Bioconjugate Chemistry, 2020

Dual-Mode Detection of Bacterial 16S Ribosomal RNA in Tissues

ACS Sensors, 2020

Preclinical Lead Optimization of a 1,2,4-Triazole Based Tankyrase Inhibitor.

Journal of medicinal chemistry, 2020

Purification of age-distinct insulin secretory granules through antigen restriction

2020

Synthesis of Iron(II)–N-Heterocyclic Carbene Complexes: Paving the Way for a New Class of Antibiotics

Molecules, 2020

Spinal Column Architecture of the Flexible SPP1 Bacteriophage Tail Tube

2020

Crystal structure of Q4D6Q6, a conserved kinetoplastid-specific protein from Trypanosoma cruzi.

Journal of structural biology, 2020

Mitochondrial cytochrome c liberates the nucleophosmin-sequestered ARF tumor suppressor in the nucleolus

2020

Flanking Regions Determine the Structure of the Poly-Glutamine in Huntingtin through Mechanisms Common among Glutamine-Rich Human Proteins.

Structure (London, England : 1993), 2020

Chemically Induced Vinylphosphonothiolate Electrophiles for Thiol–Thiol Bioconjugations

Journal of the American Chemical Society, 2020

Transfer of cGAMP into Bystander Cells via LRRC8 Volume-Regulated Anion Channels Augments STING-Mediated Interferon Responses and Anti-viral Immunity

Immunity, 2020

Eine aktivierbare Lanthanoid‐Lumineszenzsonde für die zeitgesteuerte Detektion von Nitroreduktase in lebenden Bakterien

Angewandte Chemie, 2020

An Activatable Lanthanide Luminescent Probe for Time‐Gated Detection of Nitroreductase in Live Bacteria

Angewandte Chemie International Edition, 2020

Back Cover: An Activatable Lanthanide Luminescent Probe for Time‐Gated Detection of Nitroreductase in Live Bacteria (Angew. Chem. Int. Ed. 22/2020)

Angewandte Chemie International Edition, 2020

Rücktitelbild: Eine aktivierbare Lanthanoid‐Lumineszenzsonde für die zeitgesteuerte Detektion von Nitroreduktase in lebenden Bakterien (Angew. Chem. 22/2020)

Angewandte Chemie, 2020

Advanced Mechanochemistry Device for Sustainable Synthetic Processes

ACS Omega, 2020

ZAKα Recognizes Stalled Ribosomes through Partially Redundant Sensor Domains

Molecular Cell, 2020

ITPK1 is an InsP6/ADP phosphotransferase that controls systemic phosphate homeostasis in Arabidopsis

2020

Evidence of the Reduced Abundance of Proline cis Conformation in Protein Poly Proline Tracts.

Journal of the American Chemical Society, 2020

Enhancing the Activity of Membrane Remodeling Epsin-Peptide by Trimerization

Bioorganic & Medicinal Chemistry Letters, 2020

Expanding the depth and sensitivity of cross-link identification by differential ion mobility using FAIMS

Analytical Chemistry, 2020

Transformation of Receptor Tyrosine Kinases into Glutamate Receptors and Photoreceptors

Angewandte Chemie International Edition, 2020

Transformation of Receptor Tyrosine Kinases into Glutamate Receptors and Photoreceptors

Angewandte Chemie, 2020

Local externalization of phosphatidylserine mediates developmental synaptic pruning by microglia

bioRxiv, 2020

MAS NMR detection of hydrogen bonds for protein secondary structure characterization.

Journal of biomolecular NMR, 2020

pH-Dependent Protonation of Surface Carboxylate Groups in PsbO Enables Local Buffering and Triggers Structural Changes.

Chembiochem : a European journal of chemical biology, 2020

Genetic basis of neurodevelopmental disorders in 103 Jordanian families.

Clinical genetics, 2020

Sclerotiorin Stabilizes the Assembly of Nonfibrillar Abeta42 Oligomers with Low Toxicity, Seeding Activity, and Beta-sheet Content

Journal of Molecular Biology, 2020

EHD2-mediated restriction of caveolar dynamics regulates cellular fatty acid uptake.

Proceedings of the National Academy of Sciences of the United States of America, 2020

Endophilin-A coordinates priming and fusion of neurosecretory vesicles via intersectin.

Nature communications, 2020

Vps34 derived phosphatidylinositol 3-monophosphate modulates megakaryocyte maturation and proplatelet production through late endosomes/lysosomes.

Journal of thrombosis and haemostasis : JTH, 2020

Differential diffusional properties in loose and tight docking prior to membrane fusion

bioRxiv, 2020

The importance of definitions in the study of polyQ regions: A tale of thresholds, impurities and sequence context.

Computational and structural biotechnology journal, 2020

An Efficient Coupled-Perturbed Kohn–Sham Implementation of NMR Chemical Shift Computations with Local Hybrid Functionals and Gauge-Including Atomic Orbitals

Journal of Chemical Theory and Computation, 2020

Vesicle Clustering in a Living Synapse Depends on a Synapsin Region that Mediates Phase Separation.

Cell reports, 2020

Stitching the synapse: Cross-linking mass spectrometry into resolving synaptic protein interactions

Science Advances, 2020

Modern Peptide and Protein Chemistry: Reaching New Heights

The Journal of Organic Chemistry, 2020

Dynamic interactions of CbiN and CbiM trigger activity of a cobalt energy-coupling-factor transporter

Biochimica et Biophysica Acta (BBA) - Biomembranes, 2020

Structural Determinants of Lipid Membrane Thickening at Close Distances

Biophysical Journal, 2020

Collective exchange processes reveal an active site proton cage in bacteriorhodopsin.

Communications biology, 2020

Selectivity filter instability dominates the low intrinsic activity of the TWIK-1 K2P K+ channel

Journal of Biological Chemistry, 2020

Delineating the Molecular Basis of the Calmodulin–bMunc13-2 Interaction by Cross-Linking/Mass Spectrometry—Evidence for a Novel CaM Binding Motif in bMunc13-2

Cells, 2020

The Unc13A isoform is important for phasic release and olfactory memory formation at mushroom body synapses.

Journal of neurogenetics, 2020

Stereochemical Elucidation of Natural Products from Residual Chemical Shift Anisotropies in a Liquid Crystalline Phase

Journal of the American Chemical Society, 2020

Intersectin-Mediated Clearance of SNARE Complexes Is Required for Fast Neurotransmission.

Cell reports, 2020

Super-Resolution Imaging of Tight and Adherens Junctions: Challenges and Open Questions

International Journal of Molecular Sciences, 2020

MITRAC15/COA1 promotes mitochondrial translation in a ND2 ribosome–nascent chain complex

EMBO reports, 2020

Phosphatidylinositol 3,4-bisphosphate synthesis and turnover are spatially segregated in the endocytic pathway

Journal of Biological Chemistry, 2020

Antibacterial photodynamic inactivation of antibiotic-resistant bacteria and biofilms with nanomolar photosensitizer concentrations

ACS Infectious Diseases, 2020

Interrogating surface versus intracellular transmembrane receptor populations using cell-impermeable SNAP-tag substrates

2020

Synthetic methodology towards allylic trans-cyclooctene-ethers enables modification of carbohydrates: bioorthogonal manipulation of the<i>lac</i>repressor

Chemical Science, 2020

Stimulating Macropinocytosis for Intracellular Nucleic Acid and Protein Delivery: A Combined Strategy with Membrane-Lytic Peptides to Facilitate Endosomal Escape

Bioconjugate Chemistry, 2020

Peptide-assisted intracellular delivery of biomacromolecules

Chemistry Letters, 2020

Combining free energy calculations with tailored enzyme activity assays to elucidate substrate binding of a phospho-lysine phosphatase

Chemical Science, 2020

Oxidative damage of proline residues by nitrate radicals (NO₃˙): a kinetic and product study

Organic &amp; Biomolecular Chemistry, 2020

Analysis of metabolically labeled inositol phosphate messengers by NMR

Methods in Enzymology, 2020

Host monitoring of quorum sensing during Pseudomonas aeruginosa infection.

Science (New York, N.Y.), 2019

Protein resonance assignment by BSH-CP-based 3D solid-state NMR experiments: A practical guide.

Magnetic resonance in chemistry : MRC, 2019

Defining How Oncogenic and Developmental Mutations of PIK3R1 Alter the Regulation of Class IA Phosphoinositide 3-Kinases.

Structure (London, England : 1993), 2019

Plant AtEH/Pan1 proteins drive autophagosome formation at ER-PM contact sites with actin and endocytic machinery

Nature Communications, 2019

Site-Specific Isotopic Labeling (SSIL): Access to High-Resolution Structural and Dynamic Information in Low-Complexity Proteins.

Chembiochem : a European journal of chemical biology, 2019

Phosphatidylinositol 3,4-bisphosphate synthesis and turnover are spatially segregated in the endocytic pathway.

The Journal of biological chemistry, 2019

Spermidine protects from age-related synaptic alterations at hippocampal mossy fiber-CA3 synapses.

Scientific reports, 2019

Protein Modification of Lysine with 2-(2-Styrylcyclopropyl)ethanal

Organic Letters, 2019

Metallopeptidase inhibitor 1 (TIMP‐1) promotes receptor tyrosine kinase c‐Kit signaling in colorectal cancer

Molecular Oncology, 2019

Towards the application of Tc toxins as a universal protein translocation system

Nature Communications, 2019

Asymmetric distribution of TLR3 leads to a polarized immune response in human intestinal epithelial cells.

Nature microbiology, 2019

Small-Molecule Lysophosphatidic Acid Receptor 5 (LPAR5) Antagonists: Versatile Pharmacological Tools to Regulate Inflammatory Signaling in BV-2 Microglia Cells

Frontiers in Cellular Neuroscience, 2019

Neuro‐ and hepatic toxicological profile of (<i>S</i>)‐2,4‐diaminobutanoic acid in embryonic, adolescent and adult zebrafish

Journal of Applied Toxicology, 2019

Nanoscale coupling of endocytic pit growth and stability

Science Advances, 2019

Dual Bioorthogonal Labeling of the Amyloid-β Protein Precursor Facilitates Simultaneous Visualization of the Protein and Its Cleavage Products

Journal of Alzheimer's Disease, 2019

eNOS-NO-induced small blood vessel relaxation requires EHD2-dependent caveolae stabilization

PLOS ONE, 2019

Tag and release: strategies for the intracellular cleavage of protein conjugates

Current Opinion in Chemical Biology, 2019

Pathogenesis of hypertension in a mouse model for human CLCN2 related hyperaldosteronism.

Nature communications, 2019

Retinoic acid receptor α as a novel contributor to adrenal cortex structure and function through interactions with Wnt and Vegfa signalling.

Scientific reports, 2019

Fungi as source for new bio-based materials: a patent review

Fungal Biology and Biotechnology, 2019

Structure and Dynamics of the Rhomboid Protease GlpG in Liposomes Studied by Solid-State NMR

Journal of the American Chemical Society, 2019

RIM-BP2 primes synaptic vesicles via recruitment of Munc13-1 at hippocampal mossy fiber synapses.

eLife, 2019

Metal-triggered conformational reorientation of a self-peptide bound to a disease-associated HLA-B*27 subtype

Journal of Biological Chemistry, 2019

Electron Transfer/Higher Energy Collisional Dissociation of Doubly Charged Peptide Ions: Identification of Labile Protein Phosphorylations

Journal of The American Society for Mass Spectrometry, 2019

Hybrid materials for heterogeneous photocatalytic degradation of antibiotics

Coordination Chemistry Reviews, 2019

Scalable Chemoenzymatic Synthesis of Inositol Pyrophosphates

Biochemistry, 2019

Protein kinase N controls a lysosomal lipid switch to facilitate nutrient signalling via mTORC1.

Nature cell biology, 2019

The nascent RNA binding complex SFiNX licenses piRNA-guided heterochromatin formation

Nature Structural & Molecular Biology, 2019

Phosphoinositides in the control of lysosome function and homeostasis.

Biochemical Society transactions, 2019

Probing 2H‐Indazoles as Templates for SGK1, Tie2, and SRC Kinase Inhibitors

ChemMedChem, 2019

Cysteine-Selective Phosphonamidate Electrophiles for Modular Protein Bioconjugations

Angewandte Chemie International Edition, 2019

Ethynylphosphonamidates for the Rapid and Cysteine-Selective Generation of Efficacious Antibody-Drug Conjugates

Angewandte Chemie International Edition, 2019

Two bifunctional inositol pyrophosphate kinases/phosphatases control plant phosphate homeostasis

eLife, 2019

Identification of TMEM206 proteins as pore of PAORAC/ASOR acid-sensitive chloride channels

eLife, 2019

Genetically Targeted Optical Control of an Endogenous G Protein-Coupled Receptor

Journal of the American Chemical Society, 2019

The conduction pathway of potassium channels is water free under physiological conditions

Science Advances, 2019

Poly(ADP-Ribose) Links the DNA Damage Response and Biomineralization.

Cell reports, 2019

Dynamic Nuclear Polarization Magic-Angle Spinning Nuclear Magnetic Resonance Combined with Molecular Dynamics Simulations Permits Detection of Order and Disorder in Viral Assemblies.

The journal of physical chemistry. B, 2019

Molecularly Distinct Clathrin-Coated Pits Differentially Impact EGFR Fate and Signaling.

Cell reports, 2019

First Community-Wide, Comparative Cross-Linking Mass Spectrometry Study

Analytical Chemistry, 2019

Identification of TMEM206 proteins as pore of ASOR acid-sensitive chloride channels

2019

Dysoxylactam A: A Macrocyclolipopeptide Reverses P-Glycoprotein-Mediated Multidrug Resistance in Cancer Cells

Journal of the American Chemical Society, 2019

Homeostatic scaling of active zone scaffolds maintains global synaptic strength

Journal of Cell Biology, 2019

A Recurrent Missense Variant in AP2M1 Impairs Clathrin-Mediated Endocytosis and Causes Developmental and Epileptic Encephalopathy.

American journal of human genetics, 2019

The cell adhesion protein CAR is a negative regulator of synaptic transmission.

Scientific reports, 2019

In-Cell Synthesis of Bioorthogonal Alkene Tag S-Allyl-Homocysteine and Its Coupling with Reprogrammed Translation

International Journal of Molecular Sciences, 2019

Disruption of endocytosis through chemical inhibition of clathrin heavy chain function

Nature chemical biology, 2019

Exon Inclusion Modulates Conformational Plasticity and Autoinhibition of the Intersectin 1 SH3A Domain.

Structure (London, England : 1993), 2019

Phosphoinositide switches in endocytosis and in the endolysosomal system.

Current opinion in cell biology, 2019

Rapid Synthesis of γ-Halide/Pseudohalide-Substituted Cyanine Sensors with Programmed Generation of Singlet Oxygen

Organic Letters, 2019

Integrated Approaches Toward High‐Affinity Artificial Protein Binders Obtained via Computationally Simulated Epitopes for Protein Recognition

Advanced Functional Materials, 2019

Comparison of the 3D structures of mouse and human α-synuclein fibrils by solid-state NMR and STEM

Journal of Structural Biology, 2019

Characterization of H/D exchange in type 1 pili by proton-detected solid-state NMR and molecular dynamics simulations

Journal of Biomolecular NMR, 2019

Structure of a Tc holotoxin pore provides insights into the translocation mechanism

2019

Uncommon Polyoxygenated Sesquiterpenoids from South China Sea Soft Coral Lemnalia flava

The Journal of Organic Chemistry, 2019

Sarcomililate A, an Unusual Diterpenoid with Tricyclo[11.3.0.02,16]hexadecane Carbon Skeleton, and Its Potential Biogenetic Precursors from the Hainan Soft Coral Sarcophyton mililatensis

The Journal of Organic Chemistry, 2019

Rapid active zone remodeling consolidates presynaptic potentiation.

Nature communications, 2019

Autophagy within the mushroom body protects from synapse aging in a non-cell autonomous manner

Nature Communications, 2019

Optimization of P2Y₁₂ Antagonist Ethyl 6-(4-((Benzylsulfonyl)carbamoyl)piperidin-1-yl)-5-cyano-2-methylnicotinate (AZD1283) Led to the Discovery of an Oral Antiplatelet Agent with Improved Druglike Properties

Journal of Medicinal Chemistry, 2019

Nitrobenzene method: A keystone in meso-substituted halogenated porphyrin synthesis and applications

2019

The companion of cellulose synthase 1 confers salt tolerance through a Tau-like mechanism in plants.

Nature communications, 2019

A SEPT1-based scaffold is required for Golgi integrity and function.

Journal of cell science, 2019

A pharmacological master key mechanism that unlocks the selectivity filter gate in K+ channels.

Science (New York, N.Y.), 2019

Targeted Subcellular Protein Delivery Using Cleavable Cyclic Cell-Penetrating Peptides

Bioconjugate Chemistry, 2019

Practical aspects of oligopeptide AAKLVFF as an alignment medium for the measurements of residual dipolar coupling of organic molecules

Magnetic Resonance in Chemistry, 2019

Online single and multiple analysis dictionary learning-based approach for visual object tracking

Journal of Electronic Imaging, 2019

Phosphorylation of the Bruchpilot N-terminus unlocks axonal transport of active zone building blocks

Journal of Cell Science, 2019

Optimized Fragmentation Improves the Identification of Peptides Cross-Linked by MS-Cleavable Reagents

Journal of Proteome Research, 2019

Quantitative fluorescence imaging determines the absolute number of locked nucleic acid oligonucleotides needed for suppression of target gene expression.

Nucleic acids research, 2019

EU-OPENSCREEN: A Novel Collaborative Approach to Facilitate Chemical Biology.

SLAS discovery : advancing life sciences R & D, 2019

Lethal injections with unique injection mechanism,Giftspritzen mit einzigartigem Injektionsmechanismus

BioSpektrum, 2019

Common architecture of Tc toxins from human and insect pathogenic bacteria

Science Advances, 2019

Tc toxin complexes: Assembly, membrane permeation, and protein translocation

Annual Review of Microbiology, 2019

SPHIRE-crYOLO is a fast and accurate fully automated particle picker for cryo-EM

Communications Biology, 2019

Enabling adoption of 2D-NMR for the higher order structure assessment of monoclonal antibody therapeutics

MAbs, 2019

Detection of nucleic acids and other low abundance components in native bone and osteosarcoma extracellular matrix by isotope enrichment and DNP-enhanced NMR

RSC Advances, 2019

TuPPL: Tub-tag mediated C-terminal protein–protein-ligation using complementary click-chemistry handles

Organic & Biomolecular Chemistry, 2019

Vinylphosphonites for Staudinger-induced chemoselective peptide cyclization and functionalization

Chemical Science, 2019

Harnessing 13C-labeled myo-inositol to interrogate inositol phosphate messengers by NMR

Chemical Science, 2019

Safe and Scalable Continuous Flow Azidophenylselenylation of Galactal to Prepare Galactosamine Building Blocks

Organic Process Research and Development, 2019

Automated Glycan Assembly: A Perspective

Journal of the American Chemical Society, 2019

Automated glycan assembly of Lewis type i and II oligosaccharide antigens

Chemical Science, 2019

Resistência a antibióticos: também um problema de educação?

A escola de aprender – Contributos para a sua construção, 2019

Fast and pH‐Independent Elimination of trans‐Cyclooctene by Using Aminoethyl‐Functionalized Tetrazines

Chemistry – A European Journal, 2018

Use of a sequential high throughput screening assay to identify novel inhibitors of the eukaryotic SRP-Sec61 targeting/translocation pathway.

PloS one, 2018

Optical tools for understanding the complexity of β-cell signalling and insulin release

Nature Reviews Endocrinology, 2018

Essential but sparse collagen hydroxylysyl post-translational modifications detected by DNP NMR.

Chemical communications (Cambridge, England), 2018

Lessons from the Spin-Polarization/Spin-Contamination Dilemma of Transition-Metal Hyperfine Couplings for the Construction of Exchange-Correlation Functionals

Journal of Chemical Theory and Computation, 2018

Tamoxifen therapy in a murine model of myotubular myopathy.

Nature communications, 2018

Allosteric Inhibition of a Mammalian Lectin

Journal of the American Chemical Society, 2018

CellFy-A Cell-Based Fragment Screen against C-Type Lectins.

ACS chemical biology, 2018

Modern Ligation Methods to Access Natural and Modified Proteins

CHIMIA International Journal for Chemistry, 2018

Selective increases in inter-individual variability in response to environmental enrichment in female mice

eLife, 2018

RIP2 filament formation is required for NOD2 dependent NF-κB signalling.

Nature communications, 2018

A new highly thyrotropin receptor-selective small molecule antagonist with potential for the treatment of Graves' orbitopathy.

Thyroid : official journal of the American Thyroid Association, 2018

A Computational Modeling Approach Predicts Interaction of the Antifungal Protein AFP from Aspergillus giganteus with Fungal Membranes via Its γ-Core Motif.

mSphere, 2018

A New Tool in the Quest for Biocompatible Phthalocyanines: Palladium Catalyzed Aminocarbonylation for Amide Substituted Phthalonitriles and Illustrative Phthalocyanines Thereof

Catalysts, 2018

Protein−Protein Interfaces Probed by Methyl Labeling and Proton‐Detected Solid‐State NMR Spectroscopy

ChemPhysChem, 2018

DNP NMR of biomolecular assemblies.

Journal of structural biology, 2018

Mutations in Disordered Regions Can Cause Disease by Creating Dileucine Motifs.

Cell, 2018

Mechanical signals regulate TORC2 activity.

Nature cell biology, 2018

Mechanical signals regulate TORC2 activity.

Nature Cell Biology, 2018

Membrane remodeling in clathrin-mediated endocytosis

Journal of Cell Science, 2018

SNAP-Tagged Nanobodies Enable Reversible Optical Control of a G Protein-Coupled Receptor via a Remotely Tethered Photoswitchable Ligand

ACS Chemical Biology, 2018

Structural insight into protein-aided bacterial biofilm formation

Acta Crystallographica Section A Foundations and Advances, 2018

Click‐to‐Release from trans‐Cyclooctenes: Mechanistic Insights and Expansion of Scope from Established Carbamate to Remarkable Ether Cleavage

Angewandte Chemie International Edition, 2018

Presynaptic Biogenesis Requires Axonal Transport of Lysosome-Related Vesicles.

Neuron, 2018

Long-Range Modulations of Electric Fields in Proteins.

The journal of physical chemistry. B, 2018

LRRC8 N termini influence pore properties and gating of volume-regulated anion channels (VRACs)

Journal of Biological Chemistry, 2018

Probing the Architecture, Dynamics, and Inhibition of the PI4KIIIα/TTC7/FAM126 Complex

Journal of Molecular Biology, 2018

Autoregulation of Class II Alpha PI3K Activity by Its Lipid-Binding PX-C2 Domain Module.

Molecular cell, 2018

Phasing out the bad—How SQSTM1/p62 sequesters ubiquitinated proteins for degradation by autophagy

Autophagy, 2018

CLC Chloride Channels and Transporters: Structure, Function, Physiology, and Disease

Physiological Reviews, 2018

LRRC8/VRAC anion channels are required for late stages of spermatid development in mice

Journal of Biological Chemistry, 2018

A New Fluorogenic Small-Molecule Labeling Tool for Surface Diffusion Analysis and Advanced Fluorescence Imaging of β-Site Amyloid Precursor Protein-Cleaving Enzyme 1 Based on Silicone Rhodamine: SiR-BACE1

Journal of Medicinal Chemistry, 2018

Study Of Snare-Mediated Membrane Fusion With A Novel Single Vesicle Fusion Assay

Zenodo, 2018

Study Of Snare-Mediated Membrane Fusion With A Novel Single Vesicle Fusion Assay

Zenodo, 2018

A convenient protocol for generating giant unilamellar vesicles containing SNARE proteins using electroformation

Scientific Reports, 2018

Chemical Control over T-Cell Activation in Vivo Using Deprotection of trans-Cyclooctene-Modified Epitopes

ACS Chemical Biology, 2018

Macro For Quantification Of Guv Diameter, Membrane Fluorescence Intensity, And Fret

Zenodo, 2018

Macro For Quantification Of Guv Diameter, Membrane Fluorescence Intensity, And Fret

Zenodo, 2018

Lysine-14 acetylation of histone H3 in chromatin confers resistance to the deacetylase and demethylase activities of an epigenetic silencing complex

eLife, 2018

iNEXT: a European facility network to stimulate translational structural biology.

FEBS letters, 2018

The protofilament architecture of a de novo designed coiled coil-based amyloidogenic peptide.

Journal of structural biology, 2018

Insight into small molecule binding to the neonatal Fc receptor by X-ray crystallography and 100 kHz magic-angle-spinning NMR.

PLoS biology, 2018

Efficiency of water-soluble nitroxide biradicals for dynamic nuclear polarization in rotating solids at 9.4 T: bcTol-M and cyolyl-TOTAPOL as new polarizing agents.

Chemistry (Weinheim an der Bergstrasse, Germany), 2018

Active Zone Scaffold Protein Ratios Tune Functional Diversity across Brain Synapses.

Cell reports, 2018

Mutant KRAS-driven cancers depend on PTPN11/SHP2 phosphatase.

Nature medicine, 2018

LRRC8/VRAC anion channels enhance β-cell glucose sensing and insulin secretion

Nature Communications, 2018

Ca2+-activated Cl−currents in the murine vomeronasal organ enhance neuronal spiking but are dispensable for male-male aggression

Journal of Biological Chemistry, 2018

A (+)‐Larixol Congener with High Affinity and Subtype Selectivity toward TRPC6

ChemMedChem, 2018

Arrest of trans-SNARE zippering uncovers loosely and tightly docked intermediates in membrane fusion.

The Journal of biological chemistry, 2018

PTEN suppresses axon outgrowth by down-regulating the level of detyrosinated microtubules.

PloS one, 2018

Chapter 16: 1,2,3,5,6-Penta-O-tert-butyl(dimethyl)silyl-β-d-galactofuranose: A Versatile Glycosylating Agent for Galactofuranosylation by Diego González-Salas, Carla Marino, and Mónica Guberman

Journal of Carbohydrate Chemistry, 2018

Molecular Mechanisms of Human Disease Mediated by Oncogenic and Primary Immunodeficiency Mutations in Class IA Phosphoinositide 3-Kinases.

Frontiers in Immunology, 2018

Solvation of diclofenac in water from atomistic molecular dynamics simulations - interplay between solute-solute and solute-solvent interactions.

Physical chemistry chemical physics : PCCP, 2018

Author Correction: Restoration of patterned vision with an engineered photoactivatable G protein-coupled receptor

Nature Communications, 2018

A Predictive Approach for the Optical Control of Carbonic Anhydrase II Activity

ACS Chemical Biology, 2018

Features and regulation of non-enzymatic post-translational modifications

Nature Chemical Biology, 2018

A single NaK channel conformation is not enough for non-selective ion conduction.

Nature communications, 2018

The interactome of intact mitochondria by cross-linking mass spectrometry provides evidence for coexisting respiratory supercomplexes

Molecular & Cellular Proteomics, 2018

Tracking the route of molecular oxygen in O₂-tolerant membrane-bound [NiFe] hydrogenase.

Proceedings of the National Academy of Sciences of the United States of America, 2018

Nanobodies: Chemical Functionalization Strategies and Intracellular Applications

Angewandte Chemie International Edition, 2018

Nanobodys: Strategien zur chemischen Funktionalisierung und intrazelluläre Anwendungen

Angewandte Chemie, 2018

Optical Control of a Biological Reaction–Diffusion System

Angewandte Chemie, 2018

Conditional and Reversible Activation of Class A and B G Protein-Coupled Receptors Using Tethered Pharmacology

ACS Central Science, 2018

Optical Control of a Biological Reaction–Diffusion System

Angewandte Chemie International Edition, 2018

Understanding the roles of functional peptides in designing apatite and silica nanomaterials biomimetically using NMR techniques

Current Opinion in Colloid & Interface Science, 2018

Inhibition of oxidative stress in cholinergic projection neurons fully rescues aging-associated olfactory circuit degeneration in Drosophila.

eLife, 2018

p62 filaments capture and present ubiquitinated cargos for autophagy.

The EMBO journal, 2018

Identifying Small-Molecule Inhibitors of the Clathrin Terminal Domain.

Methods in molecular biology (Clifton, N.J.), 2018

Presynaptic endocytic factors in autophagy and neurodegeneration.

Current opinion in neurobiology, 2018

Identification and Characterization of a Single High-Affinity Fatty Acid Binding Site in Human Serum Albumin.

Angewandte Chemie (International ed. in English), 2018

Tc toxin activation requires unfolding and refolding of a β-propeller

Nature, 2018

Structural changes of TasA in biofilm formation of Bacillus subtilis

Proc Natl Acad Sci U S A, 2018

Presynaptic disorders: a clinical and pathophysiological approach focused on the synaptic vesicle

Journal of Inherited Metabolic Disease, 2018

Apparent calcium dependence of vesicle recruitment

Journal of Physiology, 2018

Cytochrome c speeds up caspase cascade activation by blocking 14-3-3ϵ-dependent Apaf-1 inhibition article

Cell Death and Disease, 2018

Plant derived triterpenes from Gypsophila elegans M.Bieb. enable non-toxic delivery of gene loaded nanoplexes

J Biotechnol, 2018

A General One-Pot Synthesis of 2H-Indazoles Using an Organophosphorus-Silane System

Chemistry, 2018

A novel nitroreductase-enhanced MRI contrast agent and its potential application in bacterial imaging

Acta Pharmaceutica Sinica B, 2018

A gain-of-function mutation in the CLCN2 chloride channel gene causes primary aldosteronism

Nature Genetics, 2018

K <inf>2P</inf> TASK-2 and KCNQ1–KCNE3 K ⁺ channels are major players contributing to intestinal anion and fluid secretion

Journal of Physiology, 2018

Reply from L. P. Cid, T. J. Jentsch and F. V. Sepúlveda: intestinal electrolyte and fluid secretion – a model in trouble?

Journal of Physiology, 2018

De novo and inherited mutations in the X-linked gene CLCN4 are associated with syndromic intellectual disability and behavior and seizure disorders in males and females

Molecular Psychiatry, 2018

Novel strategy for the preparation of 3-perfluoroalkylated-2H-indazole derivatives

Tetrahedron Letters, 2018

Tub-Tag Labeling; Chemoenzymatic Incorporation of Unnatural Amino Acids

Methods in Molecular Biology, 2018

Chemoselective triazole-phosphonamidate conjugates suitable for photorelease

Chemical Communications, 2018

Pyrophosphorylation via selective phosphoprotein derivatization

Chemical Science, 2018

Structure of outer membrane protein G in lipid bilayers.

Nature communications, 2017

Phosphoinositide conversion in endocytosis and the endolysosomal system.

The Journal of biological chemistry, 2017

Coupling of exocytosis and endocytosis at the presynaptic active zone.

Neuroscience research, 2017

Facilitating identification of minimal protein binding domains by cross-linking mass spectrometry

Scientific Reports, 2017

Fluorescent labelling in living cells

Current Opinion in Biotechnology, 2017

Discovery of a Novel Series of Tankyrase Inhibitors by a Hybridization Approach.

Journal of medicinal chemistry, 2017

A Coincidence Detection Mechanism Controls PX-BAR Domain-Mediated Endocytic Membrane Remodeling via an Allosteric Structural Switch.

Developmental cell, 2017

Restoration of patterned vision with an engineered photoactivatable G protein-coupled receptor

Nature Communications, 2017

Architecture of eukaryotic mRNA 3'-end processing machinery.

Science (New York, N.Y.), 2017

Reactivity of the Sterically Demanding Siloxanediol Mes₂Si(OH)(μ‐O)Si(OH)Mes₂ Towards Water and Ether Molecules

Chemistry – A European Journal, 2017

Intersectin associates with synapsin and regulates its nanoscale localization and function.

Proceedings of the National Academy of Sciences of the United States of America, 2017

Phosphatidylinositol 4,5-bisphosphate optical uncaging potentiates exocytosis.

eLife, 2017

Plant diversity has contrasting effects on herbivore and parasitoid abundance in Centaurea jacea flower heads

Ecology and Evolution, 2017

Determination of the Local Electric Field at Au/SAM Interfaces Using the Vibrational Stark Effect

The Journal of Physical Chemistry C, 2017

Measurement of backbone hydrogen-deuterium exchange in the type III secretion system needle protein PrgI by solid-state NMR

Journal of Magnetic Resonance, 2017

Mechanical cue‐induced YAP instructs Skp2‐dependent cell cycle exit and oncogenic signaling

The EMBO Journal, 2017

Synthesis, Photophysical Properties, and Living Cell Imaging of Theranostic Half-Sandwich Iridium–4,4-Difluoro-4-bora-3a,4a-diaza-s-indacene (BODIPY) Dyads

Organometallics, 2017

A Self-Assembled Oligopeptide as a Versatile NMR Alignment Medium for the Measurement of Residual Dipolar Couplings in Methanol.

Angewandte Chemie (International ed. in English), 2017

Identification of sortase substrates by specificity profiling

Bioorganic & Medicinal Chemistry, 2017

Cross-over endocytosis of claudins is mediated by interactions via their extracellular loops.

PloS one, 2017

Optimized fragmentation schemes and data analysis strategies for proteome-wide cross-link identification

Nature Communications, 2017

Cell-permeable nanobodies for targeted immunolabelling and antigen manipulation in living cells

Nature Chemistry, 2017

Chemical Approaches to Investigate Labile Peptide and Protein Phosphorylation

Accounts of Chemical Research, 2017

Potent Prearranged Positive Allosteric Modulators of the Glucagon‐like Peptide‐1 Receptor

ChemistryOpen, 2017

Bacteriophage Tail‐Tube Assembly Studied by Proton‐Detected 4D Solid‐State NMR

Angewandte Chemie International Edition, 2017

Bacteriophage Tail‐Tube Assembly Studied by Proton‐Detected 4D Solid‐State NMR

Angewandte Chemie, 2017

Werner Reutter: A Visionary Pioneer in Molecular Glycobiology

ChemBioChem, 2017

Small Molecules Targeting Human N -Acetylmannosamine Kinase

ChemBioChem, 2017

Human Alpha Galactosidases Transiently Produced in Nicotiana benthamiana Leaves: New Insights in Substrate Specificities with Relevance for Fabry Disease

Frontiers in Plant Science, 2017

Lipid-mediated PX-BAR domain recruitment couples local membrane constriction to endocytic vesicle fission.

Nature communications, 2017

Regulation of body weight and energy homeostasis by neuronal cell adhesion molecule 1.

Nature neuroscience, 2017

mTORC1 activity repression by late endosomal phosphatidylinositol 3,4-bisphosphate

Science, 2017

Structure, dynamics and kinetics of two-component Lantibiotic Lichenicidin.

PloS one, 2017

Loss of the Na+/H+ exchanger NHE8 causes male infertility in mice by disrupting acrosome formation

Journal of Biological Chemistry, 2017

Helical Polyisocyanopeptides as Lyotropic Liquid Crystals for Measuring Residual Dipolar Couplings.

Chemistry (Weinheim an der Bergstrasse, Germany), 2017

Taming Silicon Congeners of CO and CO₂: Synthesis of Monomeric Si^II and Si^IV Chalcogenide Complexes

Angewandte Chemie International Edition, 2017

Intersectin 1 is a component of the Reelin pathway to regulate neuronal migration and synaptic plasticity in the hippocampus.

Proceedings of the National Academy of Sciences of the United States of America, 2017

Multivalent Peptide-Nanoparticle Conjugates for Influenza-Virus Inhibition

Angewandte Chemie International Edition, 2017

Multivalente Peptid-Nanopartikel-Konjugate zur Hemmung des Influenzavirus

Angewandte Chemie, 2017

Loss of Ptpn11 (Shp2) drives satellite cells into quiescence

eLife, 2017

Novel PIK3CD mutations affecting N-terminal residues of p110δ cause activated PI3Kδ syndrome (APDS) in humans.

The Journal of allergy and clinical immunology, 2017

Retrograde transport of TrkB-containing autophagosomes via the adaptor AP-2 mediates neuronal complexity and prevents neurodegeneration.

Nature communications, 2017

Direct Experimental Evidence for Halogen-Aryl π Interactions in Solution from Molecular Torsion Balances

Angewandte Chemie, 2017

A straightforward approach to N -substituted-2 H -indazol-2-amines through reductive cyclization

Tetrahedron Letters, 2017

Switchable Redox Chemistry of the Hexameric Tyrosine-Coordinated Heme Protein

The Journal of Physical Chemistry B, 2017

Backbone assignment of perdeuterated proteins by solid-state NMR using proton detection and ultrafast magic-angle spinning

Nature Protocols, 2017

Dual optical control and mechanistic insights into photoswitchable group II and III metabotropic glutamate receptors

Proceedings of the National Academy of Sciences, 2017

Rapid SNARE-mediated Fusion of Liposomes and Chromaffin Granules with Giant Unilamellar Vesicles.

2017

Identification of a Novel Benzimidazole Pyrazolone Scaffold That Inhibits KDM4 Lysine Demethylases and Reduces Proliferation of Prostate Cancer Cells

SLAS DISCOVERY: Advancing Life Sciences R&D, 2017

Remote control of glucose homeostasis in vivo using photopharmacology

Scientific Reports, 2017

Sensory domain contraction in histidine kinase CitA triggers transmembrane signaling in the membrane-bound sensor

Proceedings of the National Academy of Sciences, 2017

Amplification of a FRET Probe by Lipid-Water Partition for the Detection of Acid Sphingomyelinase in Live Cells

Angewandte Chemie International Edition, 2017

Conformational disruption of PI3Kδ regulation by immunodeficiency mutations in PIK3CD and PIK3R1.

Proceedings of the National Academy of Sciences of the United States of America, 2017

An Isolable Silicon Dicarbonate Complex from Carbon Dioxide Activation with a Silylone

Angewandte Chemie International Edition, 2017

Localization of mTORC2 activity inside cells

Journal of Cell Biology, 2017

PI(3,4,5)P3 Engagement Restricts Akt Activity to Cellular Membranes.

2017

Synaptic Vesicle Endocytosis Occurs on Multiple Timescales and Is Mediated by Formin-Dependent Actin Assembly.

Neuron, 2017

A Two-Component Adhesive: Tau Fibrils Arise from a Combination of a Well-Defined Motif and Conformationally Flexible Interactions

Journal of the American Chemical Society, 2017

Direct assessment of substrate binding to the Neurotransmitter:Sodium Symporter LeuT by solid state NMR.

eLife, 2017

Selective transport of neurotransmitters and –modulators by distinct volume-regulated LRRC8 anion channels

Journal of Cell Science, 2017

Emerin self‐assembly mechanism: role of the LEM domain

The FEBS Journal, 2017

Assembly mechanism of the α-pore-forming toxin cytolysin a from Escherichia Coli

Philosophical Transactions of the Royal Society B: Biological Sciences, 2017

Synaptic UNC13A protein variant causes increased neurotransmission and dyskinetic movement disorder

Journal of Clinical Investigation, 2017

Presynaptic Calmodulin targets: lessons from structural proteomics

Expert Review of Proteomics, 2017

Synthesis and photophysical studies of through-space conjugated [2.2]paracyclophane-based naphthalene fluorophores

RSC Adv., 2017

Complete NMR assignment and conformational analysis of 17-α-ethinylestradiol by using RDCs obtained in grafted graphene oxide

Magnetic resonance in chemistry : MRC, 2017

Structure of the competence pilus major pilin ComGC in Streptococcus pneumoniae

J Biol Chem, 2017

Sapofectosid - Ensuring non-toxic and effective DNA and RNA delivery

Int J Pharm, 2017

Direct Experimental Evidence for Halogen-Aryl pi Interactions in Solution from Molecular Torsion Balances

Angew Chem Int Ed Engl, 2017

Determination of the Absolute Configuration of (−)-Hydroxynitrilaphos and Related Biosynthetic Questions

Chemistry - A European Journal, 2017

Determination of the Absolute Configuration of (−)-Hydroxynitrilaphos and Related Biosynthetic Questions

Chemistry - A European Journal, 2017

The ClC-K2 chloride channel is critical for salt handling in the distal nephron

Journal of the American Society of Nephrology, 2017

Broad substrate tolerance of tubulin tyrosine ligase enables one-step site-specific enzymatic protein labeling

Chemical Science, 2017

Tag-Free Semi-Synthesis of the Tau Protein

Methods in Molecular Biology, 2017

Palladium-Catalyzed Asymmetric Transformations of Natural Products and Drug Molecules

Asymmetric Synthesis of Drugs and Natural Products, 2017

Optical control of GPR40 signalling in pancreatic β-cells

Chem. Sci., 2017

Optical control of a receptor-linked guanylyl cyclase using a photoswitchable peptidic hormone

Chemical Science, 2017

Frap Analysis Macro

Zenodo, 2017

Guv Membrane Linearization Macro

Zenodo, 2017

2D Dye Diffusion Model

Zenodo, 2017

Deciphering the Multisite Interactions of a Protein and Its Ligand at Atomic Resolution by Using Sensitive Paramagnetic Effects.

Chemistry (Weinheim an der Bergstrasse, Germany), 2016

Small-molecule inhibition of STOML3 oligomerization reverses pathological mechanical hypersensitivity.

Nature neuroscience, 2016

Hybrid mass spectrometry approaches in glycoprotein analysis and their usage in scoring biosimilarity

Nature Communications, 2016

Structural basis for the dissociation of α-synuclein fibrils triggered by pressure perturbation of the hydrophobic core.

Scientific reports, 2016

Dynamic Nuclear Polarization Provides New Insights into Chromophore Structure in Phytochrome Photoreceptors.

Angewandte Chemie (International ed. in English), 2016

Autophagosome Formation by Endophilin Keeps Synapses in Shape.

Neuron, 2016

5-Aryl-2-(naphtha-1-yl)sulfonamido-thiazol-4(5H)-ones as clathrin inhibitors.

Organic & biomolecular chemistry, 2016

Design of an S-Allylcysteine in situ production and incorporation system based on a novel pyrrolysyl-tRNA synthetase variant.

2016

Temperature dependence of cross-effect dynamic nuclear polarization in rotating solids: advantages of elevated temperatures.

Physical chemistry chemical physics : PCCP, 2016

Inositol polyphosphates intersect with signaling and metabolic networks via two distinct mechanisms

Proc. Natl. Acad. Sci. U.S.A., 2016

Using Hydrogen-Deuterium Exchange Mass Spectrometry to Examine Protein-Membrane Interactions.

Methods in enzymology, 2016

Diversity-oriented synthesis yields novel multistage antimalarial inhibitors.

Nature, 2016

RIM-binding protein 2 regulates release probability by fine-tuning calcium channel localization at murine hippocampal synapses.

Proceedings of the National Academy of Sciences of the United States of America, 2016

MICAL3 Flavoprotein Monooxygenase Forms a Complex with Centralspindlin and Regulates Cytokinesis

Journal of Biological Chemistry, 2016

Voltage Dependence of Conformational Dynamics and Subconducting States of VDAC-1

Biophysical Journal, 2016

Structural analysis of a signal peptide inside the ribosome tunnel by DNP MAS NMR.

Science advances, 2016

Multifunctional Benzoxazines Feature Low Polymerization Temperature and Diverse Polymer Structures.

Polymers, 2016

De novo and inherited mutations in the X-linked gene CLCN4 are associated with syndromic intellectual disability and behavior and seizure disorders in males and females.

2016

Domain motions and electron transfer dynamics in 2Fe-superoxide reductase.

Physical chemistry chemical physics : PCCP, 2016

Bis(arylmethyl)-substituted unsymmetrical phosphites for the synthesis of lipidated peptides via Staudinger-phosphite reactions.

2016

High resolution observed in 800 MHz DNP spectra of extremely rigid type III secretion needles

Journal of Biomolecular NMR, 2016

On The Potential of Dynamic Nuclear Polarization Enhanced Diamonds in Solid-State and Dissolution (13) C NMR Spectroscopy.

Chemphyschem : a European journal of chemical physics and physical chemistry, 2016

Deciphering the Interplay among Multisite Phosphorylation, Interaction Dynamics, and Conformational Transitions in a Tripartite Protein System.

2016

Chemical fragment arrays for rapid druggability assessment.

Chemical communications (Cambridge, England), 2016

Cell biology: Membrane kiss mediates hormone secretion.

Nature, 2016

Surface Binding of TOTAPOL Assists Structural Investigations of Amyloid Fibrils by Dynamic Nuclear Polarization NMR Spectroscopy.

Chembiochem : a European journal of chemical biology, 2016

The ClC-K2 Chloride Channel Is Critical for Salt Handling in the Distal Nephron.

2016

Inactivation and Anion Selectivity of Volume-Regulated VRAC Channels Depend on Carboxy-Terminal Residues of the First Extracellular Loop.

2016

The role of local and remote amino acid substitutions for optimizing fluorescence in bacteriophytochromes: A case study on iRFP.

Scientific reports, 2016

bcTol : a highly water-soluble biradical for efficient dynamic nuclear polarization of biomolecules.

Chemical communications (Cambridge, England), 2016

Quantitative and Qualitative Analysis of Surface Modified Cellulose Utilizing TGA-MS.

Materials (Basel, Switzerland), 2016

VRACs and other ion channels and transporters in the regulation of cell volume and beyond.

2016

Semi-synthesis of a tag-free O-GlcNAcylated tau protein by sequential chemoselective ligation.

2016

Current Status: Site-Specific Antibody Drug Conjugates.

2016

Stabilization of bacterially expressed erythropoietin by single site-specific introduction of short branched PEG chains at naturally occurring glycosylation sites.

2016

Allosteric Optical Control of a Class B G‐Protein‐Coupled Receptor

Angewandte Chemie International Edition, 2016

Allosterische optische Steuerung eines Klasse‐B‐G‐Protein‐gekoppelten Rezeptors

Angewandte Chemie, 2016

Using Light Sheet Fluorescence Microscopy to Image Zebrafish Eye Development

Journal of Visualized Experiments, 2016

An automated workflow for parallel processing of large multiview SPIM recordings

Bioinformatics, 2016

Studying the Conformation of a Silaffin-Derived Pentalysine Peptide Embedded in Bioinspired Silica using Solution and Dynamic Nuclear Polarization Magic-Angle Spinning NMR.

Journal of the American Chemical Society, 2016

Structural biology applications of solid state MAS DNP NMR.

Journal of magnetic resonance (San Diego, Calif. : 1997), 2016

Directing lipid transport at membrane contact sites.

Nature cell biology, 2016

The Molybdenum Active Site of Formate Dehydrogenase Is Capable of Catalyzing C-H Bond Cleavage and Oxygen Atom Transfer Reactions.

Biochemistry, 2016

Reconstitution of Fusion Proteins in Supported Lipid Bilayers for the Study of Cell Surface Receptor-Ligand Interactions in Cell-Cell Contact.

Langmuir : the ACS journal of surfaces and colloids, 2016

Modes and mechanisms of synaptic vesicle recycling.

Current opinion in neurobiology, 2016

KCNQ Potassium Channels Modulate Sensitivity of Skin Down-hair (D-hair) Mechanoreceptors.

2016

VRAC: molecular identification as LRRC8 heteromers with differential functions.

2016

Modulation of Hexadecyl-LPA-Mediated Activation of Mast Cells and Microglia by a Chemical Probe for LPA5

ChemBioChem, 2016

Ultrafast Magic-Angle Spinning: Benefits for the Acquisition of Ultrawide-Line NMR Spectra of Heavy Spin-1/2 Nuclei

ChemPhysChem, 2016

A genome-wide resource for the analysis of protein localisation in Drosophila

eLife, 2016

Design and Structural Characterization of Potent and Selective Inhibitors of Phosphatidylinositol 4 Kinase IIIβ.

Journal of medicinal chemistry, 2016

Type III phosphatidylinositol 4 kinases: structure, function, regulation, signalling and involvement in disease.

Biochemical Society transactions, 2016

A Non-canonical Voltage-Sensing Mechanism Controls Gating in K2P K(+) Channels.

Cell, 2016

Phosphatidylinositol 3-phosphates-at the interface between cell signalling and membrane traffic.

The EMBO journal, 2016

Dynamic Nuclear Polarization Enhanced MAS NMR Spectroscopy for Structural Analysis of HIV-1 Protein Assemblies.

The journal of physical chemistry. B, 2016

Peptides in headlock--a novel high-affinity and versatile peptide-binding nanobody for proteomics and microscopy.

Scientific reports, 2016

A phosphoinositide conversion mechanism for exit from endosomes.

2016

X-exome sequencing of 405 unresolved families identifies seven novel intellectual disability genes.

2016

Sample Preparation and Mounting of Drosophila Embryos for Multiview Light Sheet Microscopy

Methods in Molecular Biology, 2016

Membrane insertion of a Tc toxin in near-atomic detail

Nature Structural and Molecular Biology, 2016

Soluble oligomers of the pore-forming toxin cytolysin a from Escherichia coli are off-pathway products of pore assembly

Journal of Biological Chemistry, 2016

Distinct modes of endocytotic presynaptic membrane and protein uptake at the calyx of held terminal of rats and mice

eLife, 2016

The sclerostin-neutralizing antibody AbD09097 recognizes an epitope adjacent to sclerostin's binding site for the Wnt co-receptor LRP6

Open Biol, 2016

Chemical shift assignments and secondary structure prediction for Q4DY78, a conserved kinetoplastid-specific protein from Trypanosoma cruzi

Biomol NMR Assign, 2016

Photoswitchable diacylglycerols enable optical control of protein kinase C

Nature Chemical Biology, 2016

The Use of a Combination of RDC and Chiroptical Spectroscopy for Determination of the Absolute Configuration of Fusariumin A from the Fungus Fusarium sp

Natural products and bioprospecting, 2016

An Alignment Medium for Measuring Residual Dipolar Couplings in Pure DMSO: Liquid Crystals from Graphene Oxide Grafted with Polymer Brushes

Angewandte Chemie (International ed. in English), 2016

Intradomain Allosteric Network Modulates Calcium Affinity of the C-Type Lectin Receptor Langerin

J Am Chem Soc, 2016

Effects of Halide Ions on the Carbamidocyclophane Biosynthesis in Nostoc sp. CAVN2

Marine Drugs, 2016

Disruption of Kcc2-dependent inhibition of olfactory bulb output neurons suggests its importance in odour discrimination.

2016

5.7 Aktuelle Forschungsprojekte zu Klimawandel und Biodiversität

Warnsignal Klima: BIODIVERSITÄT, 2016

Inactivation and anion selectivity of volume-regulated anion channels (VRACs) depend on c-terminal residues of the first extracellular loop

Journal of Biological Chemistry, 2016

ChemInform Abstract: Organophosphorus-Mediated N-N Bond Formation: Facile Access to 3-Amino-2H-indazoles.

ChemInform, 2016

Organophosphorus-mediated N–N bond formation: facile access to 3-amino-2H-indazoles

Org. Biomol. Chem., 2016

Synthesis of meso-substituted porphyrins using sustainable chemical processes

Journal of Porphyrins and Phthalocyanines, 2016

Chemoselective synthesis and analysis of naturally occurring phosphorylated cysteine peptides.

2016

Interrogating the architecture of protein assemblies and protein interaction networks by cross-linking mass spectrometry.

2015

Proteome-wide profiling of protein assemblies by cross-linking mass spectrometry.

2015

Optogenetic acidification of synaptic vesicles and lysosomes.

2015

Subunit composition of VRAC channels determines substrate specificity and cellular resistance to Pt-based anti-cancer drugs.

2015

Atomic-resolution structure of cytoskeletal bactofilin by solid-state NMR

Science Advances, 2015

Hyperspectral light sheet microscopy

Nature Communications, 2015

Specificity of Collybistin-Phosphoinositide Interactions: IMPACT OF THE INDIVIDUAL PROTEIN DOMAINS.

The Journal of biological chemistry, 2015

Gottfried Schatz (1936-2015)-mitochondrial pioneer and ambassador for science.

2015

Disruption of adaptor protein 2μ (AP-2μ) in cochlear hair cells impairs vesicle reloading of synaptic release sites and hearing.

2015

Performing protein crosslinking using gas-phase cleavable chemical crosslinkers and liquid chromatography-tandem mass spectrometry.

2015

Orientation-Controlled Electrocatalytic Efficiency of an Adsorbed Oxygen-Tolerant Hydrogenase.

PloS one, 2015

Analysis of Phosphorylation-dependent Protein Interactions of Adhesion and Degranulation Promoting Adaptor Protein (ADAP) Reveals Novel Interaction Partners Required for Chemokine-directed T cell Migration.

2015

Multicolor Caged dSTORM Resolves the Ultrastructure of Synaptic Vesicles in the Brain.

2015

Versatile and Efficient Site-Specific Protein Functionalization by Tubulin Tyrosine Ligase.

2015

Optical Control of Insulin Secretion Using an Incretin Switch.

2015

Alterations in creatine metabolism observed in experimental autoimmune myocarditis using ex vivo proton magic angle spinning MRS.

NMR in biomedicine, 2015

Hopping Pits Catch Fusing Granules.

2015

Multicomponent Cascade Reactions of Unprotected Ketoses and Amino Acids – Access to a Defined Configured Quaternary Stereogenic Center

The Journal of Organic Chemistry, 2015

Editorial overview: Synthetic biomolecules: Synthetic protein modifications-a giant leap towards understanding and generating biological functions.

2015

Integrity of the Pericentriolar Material Is Essential for Maintaining Centriole Association during M Phase

PLOS ONE, 2015

Vesicular Synaptobrevin/VAMP2 Levels Guarded by AP180 Control Efficient Neurotransmission.

Neuron, 2015

Crystal structure of the dynamin tetramer.

2015

Discovery of CLC transport proteins: cloning, structure, function and pathophysiology.

2015

Hybrid Structure of the Type 1 Pilus of UropathogenicEscherichia coli

Angewandte Chemie International Edition, 2015

Light-Dark Adaptation of Channelrhodopsin Involves Photoconversion between the all-trans and 13-cis Retinal Isomers.

Biochemistry, 2015

In Vivo Evidence for Lysosome Depletion and Impaired Autophagic Clearance in Hereditary Spastic Paraplegia Type SPG11.

2015

The Soluble Periplasmic Domains of Escherichia coli Cell Division Proteins FtsQ/FtsB/FtsL Form a Trimeric Complex with Submicromolar Affinity.

2015

Probing heterobivalent binding to the endocytic AP-2 adaptor complex by DNA-based spatial screening.

2015

Theoretical aspects of Magic Angle Spinning - Dynamic Nuclear Polarization.

Journal of magnetic resonance (San Diego, Calif. : 1997), 2015

Synthesis of 6-Hydroxysphingosine and α-Hydroxy Ceramide Using a Cross-Metathesis Strategy

The Journal of Organic Chemistry, 2015

Departure gate of acidic Ca²⁺ confirmed.

2015

Gas-Phase Rearrangement in Lysine Phosphorylated Peptides During Electron-Transfer Dissociation Tandem Mass Spectrometry.

2015

A roadmap to success in photopharmacology.

2015

Crystal structure of (E)-1,2-bis-(4-bromo-2,6-di-fluoro-phen-yl)diazene.

2015

Overlapping functions of stonin 2 and SV2 in sorting of the calcium sensor synaptotagmin 1 to synaptic vesicles.

2015

Berlin Editorial.

2015

A grab to move on: ER-endosome contacts in membrane protrusion formation and neurite outgrowth.

2015

Phenothiazine-derived antipsychotic drugs inhibit dynamin and clathrin-mediated endocytosis.

2015

Phosphoinositides in endocytosis.

2015

Native chemical ligation between asparagine and valine: application and limitations for the synthesis of tri-phosphorylated C-terminal tau.

2015

Novel organic dyes for multicolor localization-based super-resolution microscopy.

Journal of biophotonics, 2015

Structural heterogeneity in microcrystalline ubiquitin studied by solid-state NMR

Protein Science, 2015