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The Ip6k1 and Ip6k2 Kinases Are Critical for Normal Renal Tubular Function
Journal of the American Society of Nephrology 2024
online lesenAn uncommon phosphorylation mode regulates the activity and protein-interactions of N-acetylglucosamine kinase
Photoswitchable Inhibitors to Optically Control Specific Kinase Activity
ACS Chemical Biology 2023
online lesenAn unconventional gatekeeper mutation sensitizes inositol hexakisphosphate kinases to an allosteric inhibitor
Real-time monitoring of the sialic acid biosynthesis pathway by NMR
Chemical Science 2023
online lesenAn unconventional gatekeeper mutation sensitizes inositol hexakisphosphate kinases to an allosteric inhibitor
eLife 2023
online lesenAn unconventional gatekeeper mutation sensitizes inositol hexakisphosphate kinases to an allosteric inhibitor
Inositol pyrophosphates activate the vacuolar transport chaperone complex in yeast by disrupting a homotypic SPX domain interaction
Nature Communications 2023
online lesenNucleolar Architecture Is Modulated by a Small Molecule, the Inositol Pyrophosphate 5-InsP7
Biomolecules 2023
online lesenAn unconventional gatekeeper mutation sensitizes inositol hexakisphosphate kinases to an allosteric inhibitor
An unconventional gatekeeper mutation sensitizes inositol hexakisphosphate kinases to an allosteric inhibitor
eLife 2023
online lesenFluorination Influences the Bioisostery of Myo‐Inositol Pyrophosphate Analogs
Chemistry – A European Journal 2023
online lesenPharmacological tools to investigate inositol polyphosphate kinases – Enzymes of increasing therapeutic relevance
Advances in Biological Regulation 2022
online lesenVersatile signaling mechanisms of inositol pyrophosphates
Current Opinion in Chemical Biology 2022
online lesenStable isotopomers of myo-inositol to uncover the complex MINPP1-dependent inositol phosphate network
Inositol Pyrophosphate-Controlled Kinetochore Architecture and Mitotic Entry in <i>S. pombe</i>
Journal of Fungi 2022
online lesenStable Isotopomers of myo-Inositol Uncover a Complex MINPP1-Dependent Inositol Phosphate Network
ACS Central Science 2022
online lesenInvestigation of a potential electrogenic transport-system for myo-inositol in the small intestine of laying hens
British Poultry Science 2022
online lesenUsing Biotinylated myo-Inositol Hexakisphosphate to Investigate Inositol Pyrophosphate–Protein Interactions with Surface-Based Biosensors
Biochemistry 2021
online lesenConversion of dietary inositol into propionate and acetate by commensal Anaerostipes associates with host health
Nature Communications 2021
online lesenDissecting the activation of insulin degrading enzyme by inositol pyrophosphates and their bisphosphonate analogs
Chemical Science 2021
online lesenDelivery of myo‐Inositol Hexakisphosphate to the Cell Nucleus with a Proline‐Based Cell‐Penetrating Peptide
Angewandte Chemie 2020
online lesenDelivery of myo‐Inositol Hexakisphosphate to the Cell Nucleus with a Proline‐Based Cell‐Penetrating Peptide
Angewandte Chemie International Edition 2020
online lesenInsP 7 is a small-molecule regulator of NUDT3-mediated mRNA decapping and processing-body dynamics
Proceedings of the National Academy of Sciences 2020
online lesenHarnessing13C-labeledmyo-inositol to interrogate inositol phosphate messengers by NMR
Chemical Science 2019
online lesenScalable Chemoenzymatic Synthesis of Inositol Pyrophosphates
Biochemistry 2019
online lesenDas Leibniz-Forschungsinstitut für Molekulare Pharmakologie (FMP) gehört zum Forschungsverbund Berlin e.V. (FVB), einem Zusammenschluss von sieben natur-, lebens- und umweltwissenschaftlichen Instituten in Berlin. Die Einrichtungen sind Mitglieder der Leibniz-Gemeinschaft.
Leibniz-Forschungsinstitut für Molekulare Pharmakologie im Forschungsverbund Berlin e.V. (FMP)
Campus Berlin-Buch
Robert-Roessle-Str. 10
13125 Berlin, Deutschland