Christian Hackenberger

Cell-Surface-Retained Peptide Additives for the Cytosolic Delivery of Functional Proteins

• Jan Vincent V. Arafiles; Jonathan Franke; Luise Franz; Jacobo Gómez-González; Kristin Kemnitz-Hassanin; Christian P. R. Hackenberger

Journal of the American Chemical Society 2023

Compact hydrophilic electrophiles enable highly efficacious high DAR ADCs with excellent in vivo PK profile

• Philipp Ochtrop; Jahaziel Jahzerah; Paul Machui; Isabelle Mai; Dominik Schumacher; Jonas Helma; Marc-André Kasper; Christian P. R. Hackenberger

Chemical Science 2023

(3+2)‐Cyclization Reactions of Unsaturated Phosphonites with Aldehydes and Thioketones

• Don S. Munasinghe; Marc‐André Kasper; Radomir Jasiński; Karolina Kula; Marcin Palusiak; Małgorzata Celeda; Grzegorz Mlostoń; Christian P. R. Hackenberger

Chemistry – A European Journal 2023

Real-time monitoring of the sialic acid biosynthesis pathway by NMR

• Jacob L. Gorenflos López; Peter Schmieder; Kristin Kemnitz-Hassanin; Hatice Ceyda Asikoglu; Arif Celik; Christian E. Stieger; Dorothea Fiedler; Stephan Hinderlich; Christian P. R. Hackenberger

Chemical Science 2023

Staudinger Ligation and Reactions – From Bioorthogonal Labeling to Next‐Generation Biopharmaceuticals

• Eleftheria Poulou; Christian P. R. Hackenberger

Israel Journal of Chemistry 2023

Targeting FLT3 with a new-generation antibody-drug conjugate in combination with kinase inhibitors for treatment of AML

• Maike Roas; Binje Vick; Marc-André Kasper; Marina Able; Harald Polzer; Marcus Gerlach; Elisabeth Kremmer; Judith Hecker; Saskia Schmitt; Andreas Stengl; Verena Waller; Natascha Hohmann; Moreno Festini; Alexander Ludwig; Lisa Rohrbacher; Tobias Herold; Kai Rejeski; Katharina Götze; Christian P.R. Hackenberger; Dominik Schumacher; Jonas Helma-Smets; Irmela Jeremias; Heinrich Leonhardt; Karsten Spiekermann

Blood 2023

Small Molecules Targeting Human UDP‐GlcNAc 2‐Epimerase

• Jacob L. Gorenflos López; Gillian L. Dornan; Nico Boback; Martin Neuenschwander; Andreas Oder; Kristin Kemnitz‐Hassanin; Peter Schmieder; Edgar Specker; Hatice Ceyda Asikoglu; Christian Oberdanner; Carola Seyffarth; Jens Peter von Kries; Daniel Lauster; Stephan Hinderlich; Christian P.R. Hackenberger

ChemBioChem 2023

Glycation Interferes with the Activity of the Bi-Functional UDP-N-Acetylglucosamine 2-Epimerase/N-Acetyl-mannosamine Kinase (GNE)

• Vanessa Hagenhaus; Jacob Gorenflos Lopez; Rebecca Rosenstengel; Carolin Neu; Christian P. R. Hackenberger; Arif Celik; Klara Weinert; Mai-Binh Nguyen; Kaya Bork; Rüdiger Horstkorte; Astrid Gesper

Biomolecules 2023

Bis‐ethynylphosphonamidates as an Modular Conjugation Platform to Generate Multi‐Functional Protein‐ and Antibody‐Drug‐Conjugates

• Marc‐André Kasper; Lukas Lassak; Annette M. Vogl; Isabelle Mai; Jonas Helma; Dominik Schumacher; Christian P. R. Hackenberger

European Journal of Organic Chemistry 2022

Atomistic insight into the essential binding event of ACE2-derived peptides to the SARS-CoV-2 spike protein

• Carolina Sarto; Sebastián Florez-Rueda; Mehrnoosh Arrar; Christian P.R. Hackenberger; Daniel Lauster; Santiago Di Lella

Biological Chemistry 2022

Synthetic α‐Helical Peptides as Potential Inhibitors of the ACE2 SARS‐CoV‐2 Interaction

• Pascal M. Engelhardt; Sebastián Florez‐Rueda; Marco Drexelius; Jörg‐Martin Neudörfl; Daniel Lauster; Christian P. R. Hackenberger; Ronald Kühne; Ines Neundorf; Hans‐Günther Schmalz

ChemBioChem 2022

Structure–Uptake Relationship Study of DABCYL Derivatives Linked to Cyclic Cell‐Penetrating Peptides for Live‐Cell Delivery of Synthetic Proteins

• Abhishek Saha; Shaswati Mandal; Jan Vincent V. Arafiles; Jacobo Gómez‐González; Christian P. R. Hackenberger; Ashraf Brik

Angewandte Chemie International Edition 2022

Design and Functional Analysis of Heterobifunctional Multivalent Phage Capsid Inhibitors Blocking the Entry of Influenza Virus

• Lutz Adam; Eva Müller; Kai Ludwig; Simon Klenk; Daniel Lauster; Susanne Liese; Andreas Herrmann; Christian P. R. Hackenberger

Bioconjugate Chemistry 2022

Modular solid-phase synthesis of electrophilic cysteine-selective ethynyl-phosphonamidate peptides

• Sarah Hansen; Jan Vincent V. Arafiles; Philipp Ochtrop; Christian P. R. Hackenberger

Chemical Communications 2022

DFT‐Guided Discovery of Ethynyl‐Triazolyl‐Phosphinates as Modular Electrophiles for Chemoselective Cysteine Bioconjugation and Profiling

• Christian Stieger; Yerin Park; Mark A. R. de Geus; Dongju Kim; Christiane Huhn; J. Sophia Slenczka; Philipp Ochtrop; Judith M. Müchler; Roderich Süssmuth; Johannes Broichhagen; Mu-Hyun Baik; Christian P.R. Hackenberger

Angewandte Chemie International Edition 2022

A silyl ether-protected building block for O-GlcNAcylated peptide synthesis to enable one-pot acidic deprotection

• Bingjia Yan; Wenyi Li; Christian P. R. Hackenberger

Organic & Biomolecular Chemistry 2021

Cellular uptake of large biomolecules enabled by cell-surface-reactive cell-penetrating peptide additives

• Anselm F. L. Schneider; Marina Kithil; M. Cristina Cardoso; Martin Lehmann; Christian P. R. Hackenberger

Nature Chemistry 2021

Synthesis and Evaluation of Non‐Hydrolyzable Phospho‐Lysine Peptide Mimics

• Anett Hauser; Eleftheria Poulou; Fabian Müller; Peter Schmieder; Christian P. R. Hackenberger

Chemistry – A European Journal 2021

The mechanism behind enhanced reactivity of unsaturated phosphorus(v) electrophiles towards thiols

• Yerin Park; Alice L. Baumann; Hyejin Moon; Stephen Byrne; Marc-André Kasper; Songhwan Hwang; Han Sun; Mu-Hyun Baik; Christian P. R. Hackenberger

Chemical Science 2021

Diethynyl Phosphinates for Cysteine‐Selective Protein Labeling and Disulfide Rebridging

• Christian E. Stieger; Luise Franz; Frieder Körlin; Christian P. R. Hackenberger

Angewandte Chemie International Edition 2021

Cell‐Permeable Nanobodies Allow Dual‐Color Super‐Resolution Microscopy in Untransfected Living Cells

• Anselm F. L. Schneider; Laila S. Benz; Martin Lehmann; Christian P. R. Hackenberger

Angewandte Chemie International Edition 2021

Discovery, X-ray structure and CPP-conjugation enabled uptake of p53/MDM2 macrocyclic peptide inhibitors

• Anselm F. L. Schneider; Joerg Kallen; Johannes Ottl; Patrick C. Reid; Sebastien Ripoche; Stephan Ruetz; Therese-Marie Stachyra; Samuel Hintermann; Christoph E. Dumelin; Christian P. R. Hackenberger; Andreas L. Marzinzik

RSC Chemical Biology 2021

Evaluation of Multivalent Sialylated Polyglycerols for Resistance Induction in and Broad Antiviral Activity against Influenza A Viruses

• Marlena N. Stadtmueller; Sumati Bhatia; Pallavi Kiran; Malte Hilsch; Valentin Reiter-Scherer; Lutz Adam; Badri Parshad; Matthias Budt; Simon Klenk; Katrin Sellrie; Daniel Lauster; Peter H. Seeberger; Christian P. R. Hackenberger; Andreas Herrmann; Rainer Haag; Thorsten Wolff

Journal of Medicinal Chemistry 2021

Phosphorylation and O-GlcNAcylation of the PHF-1 Epitope of Tau Protein Induce Local Conformational Changes of the C-Terminus and Modulate Tau Self-Assembly Into Fibrillar Aggregates

• François-Xavier Cantrelle; Anne Loyens; Xavier Trivelli; Oliver Reimann; Clément Despres; Neha S. Gandhi; Christian P. R. Hackenberger; Isabelle Landrieu; Caroline Smet-Nocca

Frontiers in Molecular Neuroscience 2021

Metabolic Glycoengineering Enables the Ultrastructural Visualization of Sialic Acids in the Glycocalyx of the Alveolar Epithelial Cell Line hAELVi

• Raphael Brandt; Sara Timm; Jacob L. Gorenflos López; Jubilant Kwame Abledu; Wolfgang M. Kuebler; Christian P. R. Hackenberger; Matthias Ochs; Elena Lopez-Rodriguez

Frontiers in Bioengineering and Biotechnology 2021

Site‐Specific Antibody Fragment Conjugates for Reversible Staining in Fluorescence Microscopy

• Jonathan Schwach; Ksenia Kolobynina; Katharina Brandstetter; Marcus Gerlach; Philipp Ochtrop; Jonas Helma; Christian P. R. Hackenberger; Hartmann Harz; M. Cristina Cardoso; Heinrich Leonhardt; Andreas Stengl

ChemBioChem 2021

Modern Peptide and Protein Chemistry: Reaching New Heights

• Christian P. R. Hackenberger; Philip E. Dawson; Yong-Xiang Chen; Hironobu Hojo

The Journal of Organic Chemistry 2020

Combining free energy calculations with tailored enzyme activity assays to elucidate substrate binding of a phospho-lysine phosphatase

• Anett Hauser; Songhwan Hwang; Han Sun; Christian P. R. Hackenberger

Chemical Science 2020

Graphene Oxide‐Cyclic R10 Peptide Nuclear Translocation Nanoplatforms for the Surmounting of Multiple‐Drug Resistance

• Zhaoxu Tu; Ievgen Donskyi; Haishi Qiao; Zhonglin Zhu; Wolfgang E. S. Unger; Christian P. R. Hackenberger; Wei Chen; Mohsen Adeli; Rainer Haag

Advanced Functional Materials 2020

Phage capsid nanoparticles with defined ligand arrangement block influenza virus entry

• Daniel Lauster; Simon Klenk; Kai Ludwig; Saba Nojoumi; Sandra Behren; Lutz Adam; Marlena Stadtmüller; Sandra Saenger; Stephanie Zimmler; Katja Hönzke; Ling Yao; Ute Hoffmann; Markus Bardua; Alf Hamann; Martin Witzenrath; Leif E. Sander; Thorsten Wolff; Andreas C. Hocke; Stefan Hippenstiel; Sacha De Carlo; Jens Neudecker; Klaus Osterrieder; Nediljko Budisa; Roland R. Netz; Christoph Böttcher; Susanne Liese; Andreas Herrmann; Christian P.R. Hackenberger

Nature Nanotechnology 2020

Recent advances of thiol-selective bioconjugation reactions

• Philipp Ochtrop; Christian Peter Richard Hackenberger

Current Opinion in Chemical Biology 2020

Chemically Induced Vinylphosphonothiolate Electrophiles for Thiol–Thiol Bioconjugations

• Alice L. Baumann; Sergej Schwagerus; Kevin Broi; Kristin Kemnitz-Hassanin; Christian E. Stieger; Nils Trieloff; Peter Schmieder; Christian P. R. Hackenberger

Journal of the American Chemical Society 2020

<i>N</i>‐Hydroxysuccinimide‐Modified Ethynylphosphonamidates Enable the Synthesis of Configurationally Defined Protein Conjugates

• Marc-André Kasper; Marcus Gerlach; Anselm Fabian Lowell Schneider; Christiane Groneberg; Philipp Ochtrop; Stefanie Boldt; Dominik Schumacher; Jonas Helma; Heinrich Leonhardt; Mathias Christmann; Christian P.R. Hackenberger

ChemBioChem 2020

Electron Transfer/Higher Energy Collisional Dissociation of Doubly Charged Peptide Ions: Identification of Labile Protein Phosphorylations

• Christian Hackenberger

Journal of The American Society for Mass Spectrometry 2019

Cysteine-Selective Phosphonamidate Electrophiles for Modular Protein Bioconjugations

• Christian Hackenberger

Angewandte Chemie International Edition 2019

Ethynylphosphonamidates for the Rapid and Cysteine-Selective Generation of Efficacious Antibody-Drug Conjugates

• Christian Hackenberger

Angewandte Chemie International Edition 2019

Tag and release: strategies for the intracellular cleavage of protein conjugates

• Christian Hackenberger

Current Opinion in Chemical Biology 2019

In-Cell Synthesis of Bioorthogonal Alkene Tag S-Allyl-Homocysteine and Its Coupling with Reprogrammed Translation

• Christian Hackenberger

International Journal of Molecular Sciences 2019

Protein Modification of Lysine with 2-(2-Styrylcyclopropyl)ethanal

• Caroline Apel; Marc-André Kasper; Christian E. Stieger; Christian P. R. Hackenberger; Mathias Christmann

Organic Letters 2019

Vinylphosphonites for Staudinger-induced chemoselective peptide cyclization and functionalization

• Marc-André Kasper; Maria Glanz; Andreas Oder; Peter Schmieder; Jens P. von Kries; Christian P. R. Hackenberger

Chemical Science 2019

TuPPL: Tub-tag mediated C-terminal protein–protein-ligation using complementary click-chemistry handles

• Andreas Stengl; Marcus Gerlach; Marc-André Kasper; Christian P. R. Hackenberger; Heinrich Leonhardt; Dominik Schumacher; Jonas Helma

Organic & Biomolecular Chemistry 2019

Targeted Subcellular Protein Delivery Using Cleavable Cyclic Cell-Penetrating Peptides

• Anselm F. L. Schneider; Antoine L. D. Wallabregue; Luise Franz; Christian P. R. Hackenberger

Bioconjugate Chemistry 2019

Tub-Tag Labeling; Chemoenzymatic Incorporation of Unnatural Amino Acids

• Christian Hackenberger

Methods in Molecular Biology 2018

Nanobodies: Chemical Functionalization Strategies and Intracellular Applications

• Christian Hackenberger

Angewandte Chemie International Edition 2018

Modern Ligation Methods to Access Natural and Modified Proteins

• Christian Hackenberger

CHIMIA International Journal for Chemistry 2018

Chemoselective triazole-phosphonamidate conjugates suitable for photorelease

• Kristina D. Siebertz; Christian P. R. Hackenberger

Chemical Communications 2018

Werner Reutter: A Visionary Pioneer in Molecular Glycobiology

• Christian Hackenberger

ChemBioChem 2017

Fluorescent labelling in living cells

• Christian Hackenberger

Current Opinion in Biotechnology 2017

Broad substrate tolerance of tubulin tyrosine ligase enables one-step site-specific enzymatic protein labeling

• Christian Hackenberger

Chemical Science 2017

Cell-permeable nanobodies for targeted immunolabelling and antigen manipulation in living cells

• Christian Hackenberger

Nature Chemistry 2017

Chemical Approaches to Investigate Labile Peptide and Protein Phosphorylation

• Christian Hackenberger

Accounts of Chemical Research 2017

Tag-Free Semi-Synthesis of the Tau Protein

• Christian Hackenberger

Methods in Molecular Biology 2017

Multivalent Peptide–Nanoparticle Conjugates for Influenza‐Virus Inhibition

• Daniel Lauster; Maria Glanz; Markus Bardua; Kai Ludwig; Markus Hellmund; Ute Hoffmann; Alf Hamann; Christoph Böttcher; Rainer Haag; Christian P. R. Hackenberger; Andreas Herrmann

Angewandte Chemie International Edition 2017

Small Molecules Targeting Human N‐Acetylmannosamine Kinase

• Stephan Hinderlich; Martin Neuenschwander; Paul R. Wratil; Andreas Oder; Michael Lisurek; Long D. Nguyen; Jens P. von Kries; Christian P. R. Hackenberger

ChemBioChem 2017

Design of an S-Allylcysteine in situ production and incorporation system based on a novel pyrrolysyl-tRNA synthetase variant.

• Exner MP; Künzl T; To TM; Ouyang Z; Schwagerus S; Hoesl MG; Hackenberger C; Lensen MC; Panke S; Budisa N

Bis(arylmethyl)-substituted unsymmetrical phosphites for the synthesis of lipidated peptides via Staudinger-phosphite reactions.

• Nischan N; Kasper MA; Mathew T; Hackenberger CP

Inhibition of the key enzyme of sialic acid biosynthesis by C6-Se modified N-acetylmannosamine analogs

• Christian Hackenberger

Chemical Science 2016

Chemoselective synthesis and analysis of naturally occurring phosphorylated cysteine peptides.

• Bertran-Vicente J; Penkert M; Nieto-Garcia O; Jeckelmann JM; Schmieder P; Krause E; Hackenberger CP

Semi-synthesis of a tag-free O-GlcNAcylated tau protein by sequential chemoselective ligation.

• Schwagerus S; Reimann O; Despres C; Smet-Nocca C; Hackenberger CP

Current Status: Site-Specific Antibody Drug Conjugates.

• Schumacher D; Hackenberger CP; Leonhardt H; Helma J

Stabilization of bacterially expressed erythropoietin by single site-specific introduction of short branched PEG chains at naturally occurring glycosylation sites.

• Hoffmann E; Streichert K; Nischan N; Seitz C; Brunner T; Schwagerus S; Hackenberger CP; Rubini M

Analysis of Phosphorylation-dependent Protein Interactions of Adhesion and Degranulation Promoting Adaptor Protein (ADAP) Reveals Novel Interaction Partners Required for Chemokine-directed T cell Migration.

• Kuropka B; Witte A; Sticht J; Waldt N; Majkut P; Hackenberger CP; Schraven B; Krause E; Kliche S; Freund C

Chemoselective Protein Modifications: Methods and Applications for the Functionalization of Viral Capsids

• Christian Hackenberger

Chemistry of Organo-Hybrids: Synthesis and Characterization of Functional Nano-Objects 2015

Applying Acylated Fucose Analogues to Metabolic Glycoengineering

• Christian Hackenberger

Bioengineering 2015

Multicolor Caged dSTORM Resolves the Ultrastructure of Synaptic Vesicles in the Brain.

• Lehmann M; Gottschalk B; Puchkov D; Schmieder P; Schwagerus S; Hackenberger CP; Haucke V; Schmoranzer J

Versatile and Efficient Site-Specific Protein Functionalization by Tubulin Tyrosine Ligase.

• Schumacher D; Helma J; Mann FA; Pichler G; Natale F; Krause E; Cardoso MC; Hackenberger CP; Leonhardt H

Editorial overview: Synthetic biomolecules: Synthetic protein modifications-a giant leap towards understanding and generating biological functions.

• Hackenberger CP; Chen PR

Gas-Phase Rearrangement in Lysine Phosphorylated Peptides During Electron-Transfer Dissociation Tandem Mass Spectrometry.

• Bertran-Vicente J; Schümann M; Hackenberger CP; Krause E

Direct access to site-specifically phosphorylated-lysine peptides from a solid-support.

• Bertran-Vicente J; Schümann M; Schmieder P; Krause E; Hackenberger CP

Orthogonal dual-modification of proteins for the engineering of multivalent protein scaffolds.

• Mühlberg M; Hoesl MG; Kuehne C; Dernedde J; Budisa N; Hackenberger CP

Native chemical ligation between asparagine and valine: application and limitations for the synthesis of tri-phosphorylated C-terminal tau.

• Reimann O; Glanz M; Hackenberger CP

Cysteine-functional polymers via thiol-ene conjugation.

• Kuhlmann M; Reimann O; Hackenberger CP; Groll J

Live-cell MRI with xenon hyper-CEST biosensors targeted to metabolically labeled cell-surface glycans.

• Witte C; Martos V; Rose HM; Reinke S; Klippel S; Schröder L; Hackenberger CP

Covalent attachment of cyclic TAT peptides to GFP results in protein delivery into live cells with immediate bioavailability.

• Nischan N; Herce HD; Natale F; Bohlke N; Budisa N; Cardoso MC; Hackenberger CP

Chemoselective bioconjugation of triazole phosphonites in aqueous media.

• Vallée MR; Majkut P; Krause D; Gerrits M; Hackenberger CP

Traceless purification and desulfurization of tau protein ligation products.

• Reimann O; Smet-Nocca C; Hackenberger CP

Side-chain cysteine-functionalized poly(2-oxazoline)s for multiple peptide conjugation by native chemical ligation.

• Schmitz M; Kuhlmann M; Reimann O; Hackenberger CP; Groll J

Site-specific PEGylation of proteins: recent developments.

• Nischan N; Hackenberger CP

More than add-on: chemoselective reactions for the synthesis of functional peptides and proteins.

• Schumacher D; Hackenberger CP

Site-specifically phosphorylated lysine peptides.

• Bertran-Vicente J; Serwa RA; Schümann M; Schmieder P; Krause E; Hackenberger CP

Controlled thioamide vs. amide formation in the thioacid-azide reaction under acidic aqueous conditions.

• Mühlberg M; Siebertz KD; Schlegel B; Schmieder P; Hackenberger CP

Chemical protein synthesis.

• Becker CF; Brik A; Dawson P; Hackenberger CP

Completion of proteomic data sets by Kd measurement using cell-free synthesis of site-specifically labeled proteins.

• Majkut P; Claußnitzer I; Merk H; Freund C; Hackenberger CP; Gerrits M

Stabilization of peptides for intracellular applications by phosphoramidate-linked polyethylene glycol chains.

• Nischan N; Chakrabarti A; Serwa RA; Bovee-Geurts PH; Brock R; Hackenberger CP

Site-specific chemical modifications of proteins

• Christian Hackenberger

Indian Journal of Chemistry 2013

Alkyne phosphonites for sequential azide-azide couplings.

• Vallée MR; Artner LM; Dernedde J; Hackenberger CP

A supramolecular peptide synthesizer.

• Bertran-Vicente J; Hackenberger CP

Traceless Staudinger acetylation of azides in aqueous buffers.

• Sowa S; Mühlberg M; Pietrusiewicz KM; Hackenberger CP

Chemoselective Staudinger-phosphite reaction of symmetrical glycosyl-phosphites with azido-peptides and polygycerols.

• Böhrsch V; Mathew T; Zieringer M; Vallée MR; Artner LM; Dernedde J; Haag R; Hackenberger CP

Glycan-specific metabolic oligosaccharide engineering of C7-substituted sialic acids.

• Möller H; Böhrsch V; Bentrop J; Bender J; Hinderlich S; Hackenberger CP

The Alzheimer's disease related tau protein as a new target for chemical protein engineering.

• Broncel M; Krause E; Schwarzer D; Hackenberger CP

Site-specific modification of proteins by the staudinger-phosphite reaction.

• Majkut P; Böhrsch V; Serwa R; Gerrits M; Hackenberger CP

Site-selective modification of proteins for the synthesis of structurally defined multivalent scaffolds.

• Artner LM; Merkel L; Bohlke N; Beceren-Braun F; Weise C; Dernedde J; Budisa N; Hackenberger CP

Identification of O-GlcNAc sites within peptides of the Tau protein and their impact on phosphorylation.

• Smet-Nocca C; Broncel M; Wieruszeski JM; Tokarski C; Hanoulle X; Leroy A; Landrieu I; Rolando C; Lippens G; Hackenberger CP

N-Azidoacetylmannosamine and N-Azidoacetylgalactosamine Incorporation into N-Glycans of Recombinantly Expressed Human Lactotransferrin by Metabolic Oligosaccharide Engineering

• Christian Hackenberger

Journal of Carbohydrate Chemistry 2011

Lewis Acid or Alkyl Halide Promoted Rearrangements of Phosphor-and Phosphinimidates to N, N-Disubstituted Phosphor-and Phosphinamidates

• Christian Hackenberger

Synthesis 2011

Staudinger-phosphonite reactions for the chemoselective transformation of azido-containing peptides and proteins.

• Vallée MR; Majkut P; Wilkening I; Weise C; Müller G; Hackenberger CP

Efficient metabolic oligosaccharide engineering of glycoproteins by UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase (GNE) knock-down.

• Möller H; Böhrsch V; Lucka L; Hackenberger CP; Hinderlich S

Synthesis of phosphonamidate peptides by Staudinger reactions of silylated phosphinic acids and esters.

• Wilkening I; del Signore G; Hackenberger CP

Perturbing the folding energy landscape of the bacterial immunity protein Im7 by site-specific N-linked glycosylation.

• Chen MM; Bartlett AI; Nerenberg PS; Friel CT; Hackenberger CP; Stultz CM; Radford SE; Imperiali B

Phosphoramidate-peptide synthesis by solution- and solid-phase Staudinger-phosphite reactions.

• Serwa RA; Swiecicki JM; Homann D; Hackenberger CP

How post-translational modifications influence amyloid formation: a systematic study of phosphorylation and glycosylation in model peptides.

• Broncel M; Falenski JA; Wagner SC; Hackenberger CP; Koksch B

Acidic and basic deprotection strategies of borane-protected phosphinothioesters for the traceless Staudinger ligation.

• Mühlberg M; Jaradat DM; Kleineweischede R; Papp I; Dechtrirat D; Muth S; Broncel M; Hackenberger CP

Enzymatically triggered amyloid formation: an approach for studying peptide aggregation.

• Broncel M; Wagner SC; Hackenberger CP; Koksch B

Towards understanding secondary structure transitions: phosphorylation and metal coordination in model peptides.

• Broncel M; Wagner SC; Paul K; Hackenberger CP; Koksch B

Werkzeug für die Chemische Biologie. Semisynthese

• Christian Hackenberger

Chemie in unserer Zeit 2010

Solid-Phase Synthesis of Phosphoramidate-Linked Glycopeptides

• Christian Hackenberger

European Journal of Organic Chemistry 2010

Site-specific PEGylation of proteins by a Staudinger-phosphite reaction

• Christian Hackenberger

Chemical Science 2010

Semisynthese. Chemie mit den Molekülen der Natur

• Christian Hackenberger

Chemie in unserer Zeit 2010

Suzuki--Miyaura Couplings on Proteins: A Simple and Ready-to-use Catalytic System in Water

• Christian Hackenberger

ChemCatChem 2010

Site-specific functionalisation of proteins by a Staudinger-type reaction using unsymmetrical phosphites.

• Böhrsch V; Serwa R; Majkut P; Krause E; Hackenberger CP

Chemically tailored multivalent virus platforms: from drug delivery to catalysis.

• Udit AK; Hackenberger CP; O'Reilly MK