- Forschung
- Karriere
- Aktuelles
- Institut
- Durchsuchen
- Spachumstellung
- Leichte Sprache
„”
Prof. Dr.
Inhibition Clathrin Mediated Endocytosis: Pitstop 1 and Pitstop 2 Chimeras
ChemMedChem 2024
online lesenSeptin-associated PIPKIγ splice variants drive centralspindlin association with the midbody via PI(4,5)P2
Directing lipid transport at membrane contact sites.
Nature cell biology 2016
online lesenA phosphoinositide conversion mechanism for exit from endosomes.
Nature 2016
online lesenSeptins As Modulators of Endo-Lysosomal Membrane Traffic.
Frontiers in Cell and Developmental Biology 2016
online lesenPanta rhei an der Plasmamembran: Phosphoinositlipide in der Endozytose
BIOspektrum 2014
online lesenComposition of isolated synaptic boutons reveals the amounts of vesicle trafficking proteins.
Science (New York, N.Y.) 2014
online lesenA novel twist in membrane dePHormation.
Developmental cell 2014
online lesenSEPT9 negatively regulates ubiquitin-dependent downregulation of EGFR.
Journal of cell science 2014
online lesenDefective tight junctions in refractory celiac disease.
Annals of the New York Academy of Sciences 2012
online lesenRegulation of phosphoinositide-metabolizing enzymes by clathrin coat proteins.
Methods in cell biology 2012
online lesenPhosphatidylinositol 4-kinase IIα function at endosomes is regulated by the ubiquitin ligase Itch.
EMBO reports 2012
online lesenLysosomal localization of GLUT8 in the testis--the EXXXLL motif of GLUT8 is sufficient for its intracellular sorting via AP1- and AP2-mediated interaction.
The FEBS journal 2009
online lesenMolecular basis for association of PIPKI gamma-p90 with clathrin adaptor AP-2.
The Journal of biological chemistry 2009
online lesenPhosphatidylinositol-(4,5)-bisphosphate regulates sorting signal recognition by the clathrin-associated adaptor complex AP2.
Molecular cell 2005
online lesenPlasmalemmal phosphatidylinositol-4,5-bisphosphate level regulates the releasable vesicle pool size in chromaffin cells.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2005
online lesenFunctional assay of effectors of ADP ribosylation factor 6 during clathrin/AP-2 coat recruitment to membranes.
Methods in enzymology 2005
online lesenStructure-activity relationships of methoctramine-related polyamines as muscular nicotinic receptor noncompetitive antagonists. 2. Role of polymethylene chain lengths separating amine functions and of substituents on the terminal nitrogen atoms.
Journal of medicinal chemistry 2002
online lesenStructure-activity relationships of methoctramine-related polyamines as muscular nicotinic receptor noncompetitive antagonists. 3. Effect of inserting the tetraamine backbone into a macrocyclic structure.
Journal of medicinal chemistry 2002
online lesenTyrosine-based endocytic motifs stimulate oligomerization of AP-2 adaptor complexes.
European journal of cell biology 2002
online lesenBinding of polyamine-containing toxins in the vestibule of the nicotinic acetylcholine receptor ion channel.
Farmaco (Societa chimica italiana : 1989) 2001
online lesenHuman stoned B interacts with AP-2 and synaptotagmin and facilitates clathrin-coated vesicle uncoating.
EMBO reports 2001
online lesenStructure-activity relationship and site of binding of polyamine derivatives at the nicotinic acetylcholine receptor.
European journal of biochemistry 2000
online lesenBinding properties of agonists and antagonists to distinct allosteric states of the nicotinic acetylcholine receptor are incompatible with a concerted model.
The Journal of biological chemistry 2000
online lesenInhibition Clathrin Mediated Endocytosis: Pitstop 1 and Pitstop 2 Chimeras
ChemMedChem 2024
online lesenSeptin-associated PIPKIγ splice variants drive centralspindlin association with the midbody via PI(4,5)P2
A SEPT1-based scaffold is required for Golgi integrity and function.
Journal of cell science 2019
online lesenIdentifying Small-Molecule Inhibitors of the Clathrin Terminal Domain.
Methods in molecular biology (Clifton, N.J.) 2018
online lesenMutations in Disordered Regions Can Cause Disease by Creating Dileucine Motifs.
Cell 2018
online lesenAdiponectin release and insulin receptor targeting share trans-Golgi-dependent endosomal trafficking routes.
Molecular metabolism 2017
online lesenDirecting lipid transport at membrane contact sites.
Nature cell biology 2016
online lesenA phosphoinositide conversion mechanism for exit from endosomes.
Nature 2016
online lesenSeptins As Modulators of Endo-Lysosomal Membrane Traffic.
Frontiers in Cell and Developmental Biology 2016
online lesenA grab to move on: ER-endosome contacts in membrane protrusion formation and neurite outgrowth.
The EMBO journal 2015
online lesenPanta rhei an der Plasmamembran: Phosphoinositlipide in der Endozytose
BIOspektrum 2014
online lesenComposition of isolated synaptic boutons reveals the amounts of vesicle trafficking proteins.
Science (New York, N.Y.) 2014
online lesenA novel twist in membrane dePHormation.
Developmental cell 2014
online lesenSEPT9 negatively regulates ubiquitin-dependent downregulation of EGFR.
Journal of cell science 2014
online lesenSpatiotemporal control of endocytosis by phosphatidylinositol-3,4-bisphosphate.
Nature 2013
online lesenPI4K2β/AP-1-based TGN-endosomal sorting regulates Wnt signaling.
Current biology : CB 2013
online lesenDefective tight junctions in refractory celiac disease.
Annals of the New York Academy of Sciences 2012
online lesenRegulation of phosphoinositide-metabolizing enzymes by clathrin coat proteins.
Methods in cell biology 2012
online lesenPhosphatidylinositol 4-kinase IIα function at endosomes is regulated by the ubiquitin ligase Itch.
EMBO reports 2012
online lesenShaping membranes for endocytosis.
Reviews of physiology, biochemistry and pharmacology 2011
online lesenEvidence that a septin diffusion barrier is dispensable for cytokinesis in budding yeast.
Biological chemistry 2011
online lesenAdaptin' endosomes for synaptic vesicle recycling, learning and memory.
The EMBO journal 2010
online lesenLysosomal localization of GLUT8 in the testis--the EXXXLL motif of GLUT8 is sufficient for its intracellular sorting via AP1- and AP2-mediated interaction.
The FEBS journal 2009
online lesenMolecular basis for association of PIPKI gamma-p90 with clathrin adaptor AP-2.
The Journal of biological chemistry 2009
online lesenArf1-GTP-induced tubule formation suggests a function of Arf family proteins in curvature acquisition at sites of vesicle budding.
The Journal of biological chemistry 2008
online lesenPhosphoinositides: regulators of membrane traffic and protein function.
FEBS letters 2007
online lesenPhosphoinositide-metabolizing enzymes at the interface between membrane traffic and cell signalling.
EMBO reports 2007
online lesenStimulation of phosphatidylinositol kinase type I-mediated phosphatidylinositol (4,5)-bisphosphate synthesis by AP-2mu-cargo complexes.
Proceedings of the National Academy of Sciences of the United States of America 2006
online lesenPhosphatidylinositol-(4,5)-bisphosphate regulates sorting signal recognition by the clathrin-associated adaptor complex AP2.
Molecular cell 2005
online lesenPlasmalemmal phosphatidylinositol-4,5-bisphosphate level regulates the releasable vesicle pool size in chromaffin cells.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2005
online lesenFunctional assay of effectors of ADP ribosylation factor 6 during clathrin/AP-2 coat recruitment to membranes.
Methods in enzymology 2005
online lesenARF6 stimulates clathrin/AP-2 recruitment to synaptic membranes by activating phosphatidylinositol phosphate kinase type Igamma.
The Journal of cell biology 2003
online lesenStructure-activity relationships of methoctramine-related polyamines as muscular nicotinic receptor noncompetitive antagonists. 2. Role of polymethylene chain lengths separating amine functions and of substituents on the terminal nitrogen atoms.
Journal of medicinal chemistry 2002
online lesenStructure-activity relationships of methoctramine-related polyamines as muscular nicotinic receptor noncompetitive antagonists. 3. Effect of inserting the tetraamine backbone into a macrocyclic structure.
Journal of medicinal chemistry 2002
online lesenTyrosine-based endocytic motifs stimulate oligomerization of AP-2 adaptor complexes.
European journal of cell biology 2002
online lesenBinding of polyamine-containing toxins in the vestibule of the nicotinic acetylcholine receptor ion channel.
Farmaco (Societa chimica italiana : 1989) 2001
online lesenHuman stoned B interacts with AP-2 and synaptotagmin and facilitates clathrin-coated vesicle uncoating.
EMBO reports 2001
online lesenStructure-activity relationship and site of binding of polyamine derivatives at the nicotinic acetylcholine receptor.
European journal of biochemistry 2000
online lesenBinding properties of agonists and antagonists to distinct allosteric states of the nicotinic acetylcholine receptor are incompatible with a concerted model.
The Journal of biological chemistry 2000
online lesenHow do acetylcholine receptor ligands reach their binding sites?
European journal of biochemistry 1999
online lesenInteractions of the nicotinic acetylcholine receptor transmembrane segments with the lipid bilayer in native receptor-rich membranes.
Biochemistry 1997
online lesenProtein and Membrane Transport in Eukaryotic Cells
Encyclopedic Reference of Genomics and Proteomics in Molecular Medicine
online lesenDas Leibniz-Forschungsinstitut für Molekulare Pharmakologie (FMP) gehört zum Forschungsverbund Berlin e.V. (FVB), einem Zusammenschluss von sieben natur-, lebens- und umweltwissenschaftlichen Instituten in Berlin. Die Einrichtungen sind Mitglieder der Leibniz-Gemeinschaft.
Leibniz-Forschungsinstitut für Molekulare Pharmakologie im Forschungsverbund Berlin e.V. (FMP)
Campus Berlin-Buch
Robert-Roessle-Str. 10
13125 Berlin, Deutschland