Fan Liu

Molecular architecture of synaptic vesicles

• Uljana Kravcenko; Max Ruwolt; Jana Kroll; Artsemi Yushkevich; Martina Zenkner; Julia Ruta; Rowaa Lotfy; Erich Wanker; Christian Rosenmund; Fan Liu; Misha Kudryashev

Proceedings of the National Academy of Sciences 2024

Redesigning error control in cross-linking mass spectrometry enables more robust and sensitive protein-protein interaction studies

• Boris Bogdanow; Max Ruwolt; Julia Ruta; Lars Mühlberg; Cong Wang; Wen-feng Zeng; Arne Elofsson; Fan Liu

Molecular Systems Biology 2024

Proteome-scale recombinant standards and a robust high-speed search engine to advance cross-linking MS-based interactomics

• Milan Avila Clasen; Max Ruwolt; Cong Wang; Julia Ruta; Boris Bogdanow; Louise U. Kurt; Zehong Zhang; Shuai Wang; Fabio C. Gozzo; Tao Chen; Paulo Carvalho; Diogo Borges Lima; Fan Liu

Nature Methods 2024

The nuclear GYF protein CD2BP2/U5–52K is required for T cell homeostasis

• Miriam Bertazzon; Almudena Hurtado-Pico; Carlos Plaza-Sirvent; Marc Schuster; Marco Preußner; Benno Kuropka; Fan Liu; Andor Zenon Amandus Kirsten; Xiao Jakob Schmitt; Benjamin König; Miguel Álvaro-Benito; Esam T. Abualrous; Gesa I. Albert; Stefanie Kliche; Florian Heyd; Ingo Schmitz; Christian Freund

Frontiers in Immunology 2024

Extensive protein pyrophosphorylation revealed in human cell lines

• Jeremy Morgan; Arpita Singh; Leonie Kurz; Michal Nadler-Holly; Max Ruwolt; Shubhra Ganguli; Sheenam Sharma; Martin Penkert; Eberhard Krause; Fan Liu; Rashna Bhandari; Dorothea Fiedler

Nature Chemical Biology 2024

RawVegetable 2.0: Refining XL-MS Data Acquisition through Enhanced Quality Control

• Louise Ulrich Kurt; Milan Avila Clasen; Ísis Venturi Biembengut; Max Ruwolt; Fan Liu; Fabio Gozzo; Diogo Borges Lima; Paulo Carvalho

Journal of Proteome Research 2024

Yeast TLDc domain proteins regulate assembly state and subcellular localization of the V-ATPase

• Samira Klössel; Ying Zhu; Lucia Amado; Daniel D Bisinski; Julia Ruta; Fan Liu; Ayelén González Montoro

The EMBO Journal 2024

Cross-link assisted spatial proteomics to map sub-organelle proteomes and membrane protein topologies

• Ying Zhu; Kerem C. Akkaya; Julia Ruta; Nanako Yokoyama; Cong Wang; Max Ruwolt; Diogo Borges Lima; Martin Lehmann; Fan Liu

Nature Communications 2024

An extended interaction site determines binding between AP180 and AP2 in clathrin mediated endocytosis

• Samuel Naudi-Fabra; Carlos A. Elena-Real; Ida Marie Vedel; Maud Tengo; Kathrin Motzny; Pin-Lian Jiang; Peter Schmieder; Fan Liu; Sigrid Milles

Nature Communications 2024

PROTEOME-SCALE RECOMBINANT STANDARDS AND A ROBUST HIGH-SPEED SEARCH ENGINE TO ADVANCE CROSS-LINKING MS-BASED INTERACTOMICS

• Milan Avila Clasen; Max Ruwolt; Louise U. Kurt; Fabio C Gozzo; Shuai Wang; Tao Chen; Paulo C Carvalho; Diogo Borges Lima; Fan Liu

Real-Time Library Search Increases Cross-Link Identification Depth across All Levels of Sample Complexity

• Max Ruwolt; Yi He; Diogo Borges Lima; William Barshop; Johannes Broichhagen; Romain Huguet; Rosa Viner; Fan Liu

Analytical Chemistry 2023

The potential of cross-linking mass spectrometry in the development of protein–protein interaction modulators

• Max Ruwolt; Ilaria Piazza; Fan Liu

Current Opinion in Structural Biology 2023

An antagonism between Spinophilin and Syd-1 operates upstream of memory-promoting presynaptic long-term plasticity

• Niraja Ramesh; Marc Escher; Oriane Turrel; Janine Lützkendorf; Tanja Matkovic; Fan Liu; Stephan Sigrist

eLife 2023

CaMKII autophosphorylation can occur between holoenzymes without subunit exchange

• Iva Lučić; Léonie Héluin; Pin-Lian Jiang; Alejandro G Castro Scalise; Cong Wang; Andreas Franz; Florian Heyd; Markus Wahl; Fan Liu; Andrew Plested

eLife 2023

Spatially resolved protein map of intact human cytomegalovirus virions

• Boris Bogdanow; Iris Gruska; Lars Mühlberg; Jonas Protze; Svea Hohensee; Barbara Vetter; Jens B. Bosse; Martin Lehmann; Mohsen Sadeghi; Lüder Wiebusch; Fan Liu

Nature Microbiology 2023

Structural Host-Virus Interactome Profiling of Intact Infected Cells

• Boris Bogdanow; Lars Mühlberg; Iris Gruska; Barbara Vetter; Julia Ruta; Arne Elofsson; Lüder Wiebusch; Fan Liu

Stitching the synapse: Cross-linking mass spectrometry into resolving synaptic protein interactions

• Fan Liu

Science Advances 2020

MITRAC15/COA1 promotes mitochondrial translation in a ND2 ribosome–nascent chain complex

• Fan Liu

EMBO reports 2020

RIM-binding protein couples synaptic vesicle recruitment to release sites

• Fan Liu

Journal of Cell Biology 2020

Expanding the depth and sensitivity of cross-link identification by differential ion mobility using FAIMS

• Fan Liu

Analytical Chemistry 2020

Interrogating the architecture of protein assemblies and protein interaction networks by cross-linking mass spectrometry.

• Liu F; Heck AJ

Proteome-wide profiling of protein assemblies by cross-linking mass spectrometry.

• Liu F; Rijkers DT; Post H; Heck AJ

The Soluble Periplasmic Domains of Escherichia coli Cell Division Proteins FtsQ/FtsB/FtsL Form a Trimeric Complex with Submicromolar Affinity.

• Glas M; van den Berg van Saparoea HB; McLaughlin SH; Roseboom W; Liu F; Koningstein GM; Fish A; den Blaauwen T; Heck AJ; de Jong L; Bitter W; de Esch IJ; Luirink J

Benchmarking multiple fragmentation methods on an orbitrap fusion for top-down phospho-proteoform characterization.

• Brunner AM; Lössl P; Liu F; Huguet R; Mullen C; Yamashita M; Zabrouskov V; Makarov A; Altelaar AF; Heck AJ

Performing protein crosslinking using gas-phase cleavable chemical crosslinkers and liquid chromatography-tandem mass spectrometry.

• Argo AS; Shi C; Liu F; Goshe MB