[Translate to Deutsch:] Portrait Thomas Jentsch

Prof. Dr. Dr.

Thomas Jentsch

Leitung Jentsch Gruppe

 +49 30 9406 2961

 jentsch@fmp-berlin.de

0000-0002-3509-2553

My lab is broadly interested in ion transport processes. Our research spans the whole spectrum from newly identifying ‘novel’ ion channels to studying how their structure determines biophysical transport properties, to determining their role in cellular and organismal processes. Besides plasma membrane channels, we elucidate the roles of ion transport in intracellular organelles. A strong focus is on the role of ion transport in physiology
and disease, which we address with genetic mouse models and human genetics.

We are particularly interested in anion channels. We discovered, for the first time, the CLC family of anion channels and transporters (1990), the molecular identity of volume-regulated VRAC/LRRC8 anion channels (2014), and of acid-activated ASOR/TMEM206 Cl channels (2019). We discovered and/or analyzed the roles of CLCs in myotonia, kidney stones, osteopetrosis, neurodegeneration, leukodystrophy, blindness, deafness, renal salt loss and hyperaldosteronism.

We also discovered all four neuronal Kv7 K channels (KCNQ2-KCNQ5), their role in epilepsy and deafness, and studied the (patho-)physiology of the K-Cl cotransporters KCC2, -3, and -4 using mouse models.

[Translate to Deutsch:] CV Thomas Jentsch
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Molekulare Physiologie & Zellbiologie

Jentsch Gruppe

FMP
Charité
NeuroCure
MDC

Auszeichnungen

Wilhelm-Vaillant-Preis for biomedical research
1992

Gottfried Wilhelm Leibniz Prize of the Deutsche Forschungsgemeinschaft (DFG)
1995

Alfred Hauptmann Preis for research on epilepsy
1998

Franz Volhard Preis for research in nephrology
1998

International Prize for Translational Neuroscience of the Gertrud-Reemtsma Foundation
1999

Feldberg Prize of the Feldberg Foundation for Anglo-German Scientific Exchange
2000

Familie Hansen Preis
2000

Prix Louis-Jeantet de médecine
2000

Elected Member of the Academia Europaea
2000

Elected Member of EMBO
2000

Ernst-Jung Preis für Medizin
2001

Elected member of the Berlin-Brandenburg Academy of Sciences and Humanities
2001

'Berliner Professorship' Lecture, Yale University
2003

Carl W. Gottschalk Distinguished Lectureship (American Physiological Society)
2004

Adolf-Fick-Prize for Physiology
2004

Elected Member of the Deutsche Akademie der Naturforscher Leopoldina/National Academy of Science
2004

Homer W. Smith Award (American Society of Nephrology)
2004

Founding member of the Akademie der Wissenschaften in Hamburg
2006

Hodgkin-Huxley-Katz Prize Lecture (Physiological Society, UK)
2006

European Research Council (ERC) Advanced Investigator
2011

Hans Ussing Award Lecture (American Physiological Society)
2012

Cátedra de Investigación Dr. García-Sainz, Univ. Autón. San Luís Potosí
2013

Awarded second European Research Council (ERC) Advanced Grant
2017

Honorary Degree (Dr. h.c.) by Medical Faculty of Hamburg University
2017

Science Prize 'Society needs Science' (by Stifterverband/Leibniz Society)
2018