Maya Polovitskaya

A protective cGAMP-mediated anti-tumor immune response can proceed without LRRC8/VRAC channels

• Fabian M.B. Thöne; Maya M. Polovitskaya; Uta E. Höpken; Armin Rehm; Thomas J. Jentsch

Journal of Biological Chemistry 2026

LRRC8/VRAC chloride and metabolite channels in signaling and volume regulation

• Fabian M.B. Thöne; Maya M. Polovitskaya; Thomas J. Jentsch

Trends in Biochemical Sciences 2025

KCNQ5 Controls Perivascular Adipose Tissue–Mediated Vasodilation

• Dmitry Tsvetkov; Johanna Schleifenbaum; Yibin Wang; Mario Kassmann; Maya M. Polovitskaya; Mohamed Ali; Sebastian Schütze; Michael Rothe; Friedrich C. Luft; Thomas J. Jentsch; Maik Gollasch

Hypertension 2024

Gain-of-function variants in CLCN7 cause hypopigmentation and lysosomal storage disease

• Maya M. Polovitskaya; Tanushka Rana; Kurt Ullrich; Simona Murko; Tatjana Bierhals; Guido Vogt; Tobias Stauber; Christian Kubisch; René Santer; Thomas J. Jentsch

Journal of Biological Chemistry 2024

Structural insights into anion selectivity and activation mechanism of LRRC8 volume-regulated anion channels

• Heng Liu; Maya M. Polovitskaya; Linlin Yang; Meiling Li; Hongyue Li; Zhen Han; Jianguo Wu; Qiansen Zhang; Thomas J. Jentsch; Jun Liao

Cell Reports 2023

Molecular basis of ClC-6 function and its impairment in human disease

• Bing Zhang; Sensen Zhang; Maya M. Polovitskaya; Jingbo Yi; Binglu Ye; Ruochong Li; Xueying Huang; Jian Yin; Sebastian Neuens; Tom Balfroid; Julie Soblet; Daphné Vens; Alec Aeby; Xiaoling Li; Jinjin Cai; Yingcai Song; Yuanxi Li; Marco Tartaglia; Yang Li; Thomas J. Jentsch; Maojun Yang; Zhiqiang Liu

Science Advances 2023

Gating choreography and mechanism of the human proton-activated chloride channel ASOR

• Chongyuan Wang; Maya M. Polovitskaya; Bryce D. Delgado; Thomas J. Jentsch; Stephen B. Long

Science Advances 2022

Unique variants in CLCN3, encoding an endosomal anion/proton exchanger, underlie a spectrum of neurodevelopmental disorders

• Maya Polovitskaya

The American Journal of Human Genetics 2021

A Recurrent Gain-of-Function Mutation in CLCN6, Encoding the ClC-6 Cl−/H+-Exchanger, Causes Early-Onset Neurodegeneration

• Maya Polovitskaya

The American Journal of Human Genetics 2020

LRRC8 N termini influence pore properties and gating of volume-regulated anion channels (VRACs)

• Pingzheng Zhou; Maya M. Polovitskaya; Thomas J. Jentsch

Journal of Biological Chemistry 2018