Jan Vincent Arafiles

Grafting Hydrophobic Amino Acids Critical for Inhibition of Protein–Protein Interactions on a Cell-Penetrating Peptide Scaffold

• Yuki Nagano; Jan Vincent V. Arafiles; Keiko Kuwata; Yoshimasa Kawaguchi; Miki Imanishi; Hisaaki Hirose; Shiroh Futaki

Molecular Pharmaceutics 2022

Artificial Nanocage Formed via Self-Assembly of β-Annulus Peptide for Delivering Biofunctional Proteins into Cell Interiors

• Kentarou Sakamoto; Hiroto Furukawa; Jan Vincent V. Arafiles; Miki Imanishi; Kazunori Matsuura; Shiroh Futaki

Bioconjugate Chemistry 2022

Stearylated Macropinocytosis-Inducing Peptides Facilitating the Cellular Uptake of Small Extracellular Vesicles

• Yuna Nakagawa; Jan Vincent V. Arafiles; Yoshimasa Kawaguchi; Ikuhiko Nakase; Hisaaki Hirose; Shiroh Futaki

Bioconjugate Chemistry 2022

Structure–Uptake Relationship Study of DABCYL Derivatives Linked to Cyclic Cell‐Penetrating Peptides for Live‐Cell Delivery of Synthetic Proteins

• Abhishek Saha; Shaswati Mandal; Jan Vincent V. Arafiles; Jacobo Gómez‐González; Christian P. R. Hackenberger; Ashraf Brik

Angewandte Chemie International Edition 2022

Struktur‐Wirkungsbeziehung von an zyklische Zell‐penetrierende Peptide gebundenen DABCYL‐Derivaten für den Transport von synthetischen Proteinen in lebende Zellen

• Abhishek Saha; Shaswati Mandal; Jan Vincent V. Arafiles; Jacobo Gómez‐González; Christian P. R. Hackenberger; Ashraf Brik

Angewandte Chemie 2022

Modular solid-phase synthesis of electrophilic cysteine-selective ethynyl-phosphonamidate peptides

• Sarah Hansen; Jan Vincent V. Arafiles; Philipp Ochtrop; Christian P. R. Hackenberger

Chemical Communications 2022

Piezo1 activation using Yoda1 inhibits macropinocytosis in A431 human epidermoid carcinoma cells

• Masashi Kuriyama; Hisaaki Hirose; Toshihiro Masuda; Masachika Shudou; Jan Vincent V. Arafiles; Miki Imanishi; Masashi Maekawa; Yuji Hara; Shiroh Futaki

Scientific Reports 2022

Chemical passports to cross biological borders

• Arafiles, J.V.V.; Futaki, S.

Nature Chemistry 2021

Cover Picture: Liquid Droplet Formation and Facile Cytosolic Translocation of IgG in the Presence of Attenuated Cationic Amphiphilic Lytic Peptides (Angew. Chem. Int. Ed. 36/2021)

• Takahiro Iwata; Hisaaki Hirose; Kentarou Sakamoto; Yusuke Hirai; Jan Vincent V. Arafiles; Misao Akishiba; Miki Imanishi; Shiroh Futaki

Angewandte Chemie International Edition 2021

Use of homoarginine to obtain attenuated cationic membrane lytic peptides.

• Sakamoto K; Akishiba M; Iwata T; Arafiles JVV; Imanishi M; Futaki S

Bioorganic & medicinal chemistry letters 2021

Liquid Droplet Formation and Facile Cytosolic Translocation of IgG in the Presence of Attenuated Cationic Amphiphilic Lytic Peptides

• Takahiro Iwata; Hisaaki Hirose; Kentarou Sakamoto; Yusuke Hirai; Jan Vincent V. Arafiles; Misao Akishiba; Miki Imanishi; Shiroh Futaki

Angewandte Chemie 2021

Titelbild: Liquid Droplet Formation and Facile Cytosolic Translocation of IgG in the Presence of Attenuated Cationic Amphiphilic Lytic Peptides (Angew. Chem. 36/2021)

• Takahiro Iwata; Hisaaki Hirose; Kentarou Sakamoto; Yusuke Hirai; Jan Vincent V. Arafiles; Misao Akishiba; Miki Imanishi; Shiroh Futaki

Angewandte Chemie 2021

Discovery of a Macropinocytosis-Inducing Peptide Potentiated by Medium-Mediated Intramolecular Disulfide Formation

• Arafiles, J.V.V.; Hirose, H.; Hirai, Y.; Kuriyama, M.; Sakyiamah, M.M.; Nomura, W.; Sonomura, K.; Imanishi, M.; Otaka, A.; Tamamura, H.; Futaki, S.

Angewandte Chemie - International Edition 2021

Piezo1 activation using Yoda1 inhibits macropinocytosis and proliferation of cancer cells

• Kuriyama M; Hirose H; Masuda T; Shudou M; Arafiles JVV; Imanishi M; Maekawa M; Hara Y; Futaki S

Discovery of a Macropinocytosis‐Inducing Peptide Potentiated by Medium‐Mediated Intramolecular Disulfide Formation

• Jan Vincent V. Arafiles; Hisaaki Hirose; Yusuke Hirai; Masashi Kuriyama; Maxwell Mamfe Sakyiamah; Wataru Nomura; Kazuhiro Sonomura; Miki Imanishi; Akira Otaka; Hirokazu Tamamura; Shiroh Futaki

Angewandte Chemie 2021

A facile combinatorial approach to construct a ratiometric fluorescent sensor: application for the real-time sensing of cellular pH changes

• Eiji Nakata; Hisaaki Hirose; Khongorzul Gerelbaatar; Jan Vincent V. Arafiles; Zhengxiao Zhang; Shiroh Futaki; Takashi Morii

Chemical Science 2021

Liquid Droplet Formation and Facile Cytosolic Translocation of IgG in the Presence of Attenuated Cationic Amphiphilic Lytic Peptides

• Takahiro Iwata; Hisaaki Hirose; Kentarou Sakamoto; Yusuke Hirai; Jan Vincent V. Arafiles; Misao Akishiba; Miki Imanishi; Shiroh Futaki

Angewandte Chemie International Edition 2021