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The molecular mechanisms mediating class II PI 3‐kinase function in cell physiology
The FEBS Journal 2021
online lesenDissecting the activation of insulin degrading enzyme by inositol pyrophosphates and their bisphosphonate analogs
Chemical Science 2021
online lesenMolecular Mechanisms of Human Disease Mediated by Oncogenic and Primary Immunodeficiency Mutations in Class IA Phosphoinositide 3-Kinases.
Frontiers in Immunology 2018
online lesenProbing the Architecture, Dynamics, and Inhibition of the PI4KIIIα/TTC7/FAM126 Complex
Journal of Molecular Biology 2018
online lesenArchitecture of eukaryotic mRNA 3'-end processing machinery.
Science (New York, N.Y.) 2017
online lesenNovel PIK3CD mutations affecting N-terminal residues of p110δ cause activated PI3Kδ syndrome (APDS) in humans.
The Journal of allergy and clinical immunology 2017
online lesenConformational disruption of PI3Kδ regulation by immunodeficiency mutations in PIK3CD and PIK3R1.
Proceedings of the National Academy of Sciences of the United States of America 2017
online lesenUsing Hydrogen-Deuterium Exchange Mass Spectrometry to Examine Protein-Membrane Interactions.
Methods in enzymology 2016
online lesenDiversity-oriented synthesis yields novel multistage antimalarial inhibitors.
Nature 2016
online lesenDesign and Structural Characterization of Potent and Selective Inhibitors of Phosphatidylinositol 4 Kinase IIIβ.
Journal of medicinal chemistry 2016
online lesenType III phosphatidylinositol 4 kinases: structure, function, regulation, signalling and involvement in disease.
Biochemical Society transactions 2016
online lesenDas Leibniz-Forschungsinstitut für Molekulare Pharmakologie (FMP) gehört zum Forschungsverbund Berlin e.V. (FVB), einem Zusammenschluss von sieben natur-, lebens- und umweltwissenschaftlichen Instituten in Berlin. Die Einrichtungen sind Mitglieder der Leibniz-Gemeinschaft.
Leibniz-Forschungsinstitut für Molekulare Pharmakologie im Forschungsverbund Berlin e.V. (FMP)
Campus Berlin-Buch
Robert-Roessle-Str. 10
13125 Berlin, Deutschland