Edgar Specker

Enhanced Properties of a Benzimidazole Benzylpyrazole Lysine Demethylase Inhibitor: Mechanism-of-Action, Binding Site Analysis, and Activity in Cellular Models of Prostate Cancer

• Carter, D. M.
• Specker, E.
• Malecki, P. H.
• Przygodda, J.
• Dudaniec, K.
• Weiss, M. S.
• Heinemann, U.
• Nazaré, M., &
• Gohlke, U.

Journal of Medicinal Chemistry 2021, 64, 14266-14282

Topical inflammasome inhibition with disulfiram prevents irritant contact dermatitis

• Bonnekoh, H.
• Vera, C.
• Abad-Perez, A.
• Radetzki, S.
• Neuenschwander, M.
• Specker, E.
• Mahnke, N. A.
• Frischbutter, S.
• Latz, E.
• Nazaré, M.
• Kries, J. v.
• Maurer, M.
• Scheffel, J., &
• Krause, K.

Clinical and Translational Allergy 2021, 11, e12045

NMR quality control of fragment libraries for screening

• Sreeramulu, S.
• Richter, C.
• Kuehn, T.
• Azzaoui, K.
• Blommers, M. J. J.
• Del Conte, R.
• Fragai, M.
• Trieloff, N.
• Schmieder, P.
• Nazare, M.
• Specker, E.
• Ivanov, V.
• Oschkinat, H.
• Banci, L., &
• Schwalbe, H.

Journal of Biomolecular NMR 2020, 74, 555-563

A New Highly Thyrotropin Receptor-Selective Small-Molecule Antagonist with Potential for the Treatment of Graves' Orbitopathy

• Marcinkowski, P.
• Hoyer, I.
• Specker, E.
• Furkert, J.
• Rutz, C.
• Neuenschwander, M.
• Sobottka, S.
• Sun, H.
• Nazare, M.
• Berchner-Pfannschmidt, U.
• Von Kries, J. P.
• Eckstein, A.
• Schülein, R., &
• Krause, G.

Thyroid 2019, 29, 111-123

EU-OPENSCREEN: A Novel Collaborative Approach to Facilitate Chemical Biology

• Brennecke, P.
• Rasina, D.
• Aubi, O.
• Herzog, K.
• Landskron, J.
• Cautain, B.
• Vicente, F.
• Quintana, J.
• Mestres, J.
• Stechmann, B.
• Ellinger, B.
• Brea, J.
• Kolanowski, J. L.
• Pilarski, R.
• Orzaez, M.
• Pineda-Lucena, A.
• Laraia, L.
• Nami, F.
• Zielenkiewicz, P.
• Paruch, K.
• Hansen, E.
• Kries, J. P.
• Neuenschwander, M.
• Specker, E.
• Bartunek, P.
• Simova, S.
• Lesnikowski, Z.
• Krauss, S.
• Lehtio, L.
• Bilitewski, U.
• Bronstrup, M.
• Tasken, K.
• Jirgensons, A.
• Lickert, H.
• Clausen, M. H.
• Andersen, J. H.
• Vicent, M. J.
• Genilloud, O.
• Martinez, A.
• Nazare, M.
• Fecke, W., &
• Gribbon, P.

Slas Discovery 2019, 24, 398-413

Small-Molecule Lysophosphatidic Acid Receptor 5 (LPAR5) Antagonists: Versatile Pharmacological Tools to Regulate Inflammatory Signaling in BV-2 Microglia Cells

• Plastira, I.
• Joshi, L.
• Bernhart, E.
• Schoene, J.
• Specker, E.
• Nazare, M., &
• Sattler, W.

Frontiers in Cellular Neuroscience 2019, 13, 531